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Biology and Biochemistry

D-Index
60
Citations
10808
World Ranking
12130
National Ranking
5191

Overview

Robert V. Stahelin is affiliated with Purdue University West Lafayette in the United States. Their research focuses mainly on the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with particular attention to subfields such as Infectious Diseases, Molecular Biology, Epidemiology, Cell Biology, and Public Health, Environmental, and Occupational Health.

Their work extensively covers topics including:

  • Viral Infections and Outbreaks Research
  • Hepatitis B Virus Studies
  • SARS-CoV-2 and COVID-19 Research
  • Lipid Membrane Structure and Behavior
  • Viral Infections and Vectors
  • Viral gastroenteritis research and epidemiology
  • Mosquito-borne diseases and control

Stahelin's frequent coauthors include Prem P. Chapagain, Monica L. Husby, Souad Amiar, Bernard S. Gerstman, and Caroline B. Plescia.

They have published primarily in several key scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Preprints.org
  • Viruses
  • Journal of Lipid Research

Notable recent publications by Stahelin include:

  • SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles, 2020, Journal of Biological Chemistry
  • Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response, 2021, Cell Reports
  • Drp1 Tubulates the ER in a GTPase-Independent Manner, 2020, Molecular Cell
  • Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization, 2022, Science Advances
  • Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding, 2022, EMBO Reports

Best Publications

  • Membrane-protein interactions in cell signaling and membrane trafficking.

    Wo nhwa Cho;Robert V. Stahelin

  • A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

    Alassane Mbengue;Souvik Bhattacharjee;Trupti Pandharkar;Haining Liu

  • Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

    Dimitrios Karathanassis;Robert V. Stahelin;Jerónimo Bravo;Olga Perisic

  • Membrane binding and subcellular targeting of C2 domains.

    Wonhwa Cho;Robert V. Stahelin

  • Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.

    Sahar A. Saddoughi;Salih Gencer;Yuri K. Peterson;Katherine E. Ward

  • Contrasting Membrane Interaction Mechanisms of AP180 N-terminal Homology (ANTH) and Epsin N-terminal Homology (ENTH) Domains*

    Robert V. Stahelin;Fei Long;Brian J. Peter;Diana Murray

  • Phosphatidylinositol 3-Phosphate Induces the Membrane Penetration of the FYVE Domains of Vps27p and Hrs

    Robert V. Stahelin;Fei Long;Karthikeyan Diraviyam;Karol S. Bruzik

  • Differential roles of ionic, aliphatic, and aromatic residues in membrane-protein interactions: a surface plasmon resonance study on phospholipases A2.

    Robert V. Stahelin;Wonhwa Cho

  • Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox.

    Robert V. Stahelin;Aura Burian;Karol S. Bruzik;Diana Murray

  • Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains.

    Bharath Ananthanarayanan;Robert V. Stahelin;Michelle A. Digman;Wonhwa Cho

  • The mechanism of membrane targeting of human sphingosine kinase 1

    Robert V. Stahelin;Jeong H. Hwang;Jin Hahn Kim;Zee Yong Park

  • Mechanism of Diacylglycerol-induced Membrane Targeting and Activation of Protein Kinase Cδ

    Heather R. Melowic;Robert V. Stahelin;Nichole R. Blatner;Wen Tian

  • Roles of Ionic Residues of the C1 Domain in Protein Kinase C-α Activation and the Origin of Phosphatidylserine Specificity

    Lenka Bittova;Robert V. Stahelin;Wonhwa Cho

  • The molecular basis of differential subcellular localization of C2 domains of protein kinase C-α and group IVa cytosolic phospholipase A2

    Robert V. Stahelin;John D. Rafter;Sudipto Das;Wonhwa Cho

  • Membrane binding assays for peripheral proteins.

    Wonhwa Cho;Lenka Bittova;Robert V. Stahelin

  • Ceramide 1-Phosphate Acts as a Positive Allosteric Activator of Group IVA Cytosolic Phospholipase A2α and Enhances the Interaction of the Enzyme with Phosphatidylcholine

    Preeti Subramanian;Robert V. Stahelin;Zdzislaw Szulc;Alicja Bielawska

  • Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain.

    Robert V. Stahelin;Preeti Subramanian;Mohsin Vora;Wonhwa Cho

  • Lipid binding domains: more than simple lipid effectors

    Robert V. Stahelin

  • Diacylglycerol-induced membrane targeting and activation of protein kinase Cepsilon: mechanistic differences between protein kinases Cdelta and Cepsilon.

    Robert V. Stahelin;Michelle A. Digman;Michelle A. Digman;Martina Medkova;Bharath Ananthanarayanan

  • Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell.

    Souvik Bhattacharjee;Robert V. Stahelin;Robert V. Stahelin;Kaye D. Speicher;David W. Speicher

Frequent Co-Authors

Wonhwa Cho
Wonhwa Cho University of Illinois at Chicago
Charles E. Chalfant
Charles E. Chalfant Virginia Commonwealth University
Michelle A. Digman
Michelle A. Digman University of California, Irvine
Tatiana G. Kutateladze
Tatiana G. Kutateladze University of Colorado Denver
Enrico Gratton
Enrico Gratton University of California, Irvine
Kasturi Haldar
Kasturi Haldar University of Notre Dame
Yi Pang
Yi Pang University of Akron
Vladislav V. Verkhusha
Vladislav V. Verkhusha Albert Einstein College of Medicine
Besim Ogretmen
Besim Ogretmen Medical University of South Carolina
Roger L. Williams
Roger L. Williams University of Cambridge

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