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Immunology

D-Index
59
Citations
14278
World Ranking
3413
National Ranking
296

Overview

Michael R. Edwards is affiliated with Imperial College London in the United Kingdom. Their research primarily focuses on medicine, with significant contributions to immunology and microbiology. The subfields covered in their work include immunology, physiology, pulmonary and respiratory medicine, epidemiology, and molecular biology.

The scientist's research explores several main topics, notably asthma and respiratory diseases, IL-33, ST2, and ILC pathways, respiratory viral infections, chronic obstructive pulmonary disease (COPD), respiratory and cough-related research, inflammasomes and immune disorders, and immune cell function and interaction.

Key recent publications include the following:

  • IL-33-induced neutrophilic inflammation and NETosis underlie rhinovirus-triggered exacerbations of asthma, 2023, Mucosal Immunology
  • Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19, 2023, Nature Communications
  • Virus-induced Volatile Organic Compounds Are Detectable in Exhaled Breath during Pulmonary Infection, 2021, American Journal of Respiratory and Critical Care Medicine
  • Obesity dysregulates the pulmonary antiviral immune response, 2023, Nature Communications
  • Echinacea Purpurea For the Long-Term Prevention of Viral Respiratory Tract Infections During Covid-19 Pandemic: A Randomized, Open, Controlled, Exploratory Clinical Study, 2022, Frontiers in Pharmacology

Frequent collaborators include:

  • Sebastian L. Johnston
  • David J. Jackson
  • Aran Singanayagam
  • Eteri Regis
  • Tatiana Kebadze

Publications related to Michael R. Edwards have appeared most often in bioRxiv (Cold Spring Harbor Laboratory), with six publications, followed by Nature Communications with three publications. Additional venues include Scientific Reports, Thorax, and the Journal of Allergy and Clinical Immunology.

Best Publications

  • Role of deficient type III interferon-λ production in asthma exacerbations

    Marco Contoli;Simon D Message;Vasile Laza-Stanca;Michael R Edwards

  • The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

    Marjolaine Vareille;Elisabeth Kieninger;Michael R. Edwards;Nicolas Regamey

  • IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo

    David J. Jackson;David J. Jackson;Heidi Makrinioti;Batika M. J. Rana;Betty W. H. Shamji

  • Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease.

    Michael R. Edwards;Nathan W. Bartlett;Deborah Clarke;Mark Birrell

  • Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

    Nathan W Bartlett;Ross P Walton;Michael R Edwards;Juliya Aniscenko

  • Experimental Rhinovirus Infection as a Human Model of Chronic Obstructive Pulmonary Disease Exacerbation

    Patrick Mallia;Simon D. Message;Vera Gielen;Marco Contoli

  • Azithromycin induces anti-viral responses in bronchial epithelial cells

    V. Gielen;Sebastian L. Johnston;Michael R. Edwards

  • Control of lupus nephritis by changes of gut microbiota

    Qinghui Mu;Husen Zhang;Xiaofeng Liao;Kaisen Lin

  • Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

    Janine Beale;Janine Beale;Janine Beale;Annabelle Jayaraman;Annabelle Jayaraman;Annabelle Jayaraman;David J. Jackson;Jonathan D. R. Macintyre

  • Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation

    Marie Toussaint;David J. Jackson;Dawid Swieboda;Anabel Guedan

  • Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium

    Louise Slater;Nathan Bartlett;Jennifer J. Haas;Jie Zhu

  • Toll-Like Receptor 3 Is Induced by and Mediates Antiviral Activity against Rhinovirus Infection of Human Bronchial Epithelial Cells

    Christopher A. Hewson;Alice Jardine;Michael R. Edwards;Vasile Laza-Stanca

  • Rhinovirus 16–induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients

    Annemarie Sykes;Michael R. Edwards;Jonathan MacIntyre;Ajerico Del Rosario

  • Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells.

    M. R. Khaitov;V. Laza-Stanca;M. R. Edwards;R. P. Walton

  • The microbiology of asthma

    Michael R. Edwards;Nathan W. Bartlett;Tracy Hussell;Peter Openshaw

  • Impaired innate interferon induction in severe therapy resistant atopic asthmatic children.

    M R Edwards;N Regamey;M Vareille;E Kieninger

  • Viral infections in allergy and immunology: How allergic inflammation influences viral infections and illness

    Michael R. Edwards;Katherine Strong;Aoife Cameron;Ross P. Walton

  • Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

    Aran Singanayagam;Nicholas Glanville;Jason L. Girkin;Yee Man Ching

  • Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells

    M Contoli;K. Ito;A. Padovani;D. Poletti

  • Anaerobic bacterial metabolism in the ancient eukaryote Giardia duodenalis.

    D.M. Brown;J.A. Upcroft;M.R. Edwards;P. Upcroft

  • Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells

    Aline Schögler;Brigitte S. Kopf;Michael R. Edwards;Sebastian L. Johnston

Frequent Co-Authors

Sebastian L. Johnston
Sebastian L. Johnston Imperial College London
Patrick Mallia
Patrick Mallia Imperial College London
Nathan W. Bartlett
Nathan W. Bartlett Imperial College London
Alberto Papi
Alberto Papi University of Ferrara
Nikolaos G. Papadopoulos
Nikolaos G. Papadopoulos National and Kapodistrian University of Athens
Leigh A. Knodler
Leigh A. Knodler Washington State University
Maria G. Belvisi
Maria G. Belvisi Imperial College London
Cezmi A. Akdis
Cezmi A. Akdis University of Zurich
Ian Sabroe
Ian Sabroe University of Sheffield
Jadwiga A. Wedzicha
Jadwiga A. Wedzicha Imperial College London

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