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Biology and Biochemistry

D-Index
74
Citations
27816
World Ranking
5472
National Ranking
43

Overview

Andreas Villunger is affiliated with Innsbruck Medical University in Austria, contributing extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research output encompasses 104 publications focusing predominantly on molecular biology, cell biology, oncology, immunology, and cancer research.

The scientist's work centers on several key topics, including microtubule and mitosis dynamics, ubiquitin and proteasome pathways, cell death mechanisms and regulation, cancer-related molecular pathways, DNA repair mechanisms, microRNA in disease regulation, and epigenetics and DNA methylation.

Frequent publication venues for Andreas Villunger include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • FEBS Journal
  • Cell Death and Differentiation
  • The EMBO Journal
  • EMBO Reports

The scientist has collaborated frequently with peers such as Valentina C. Sladky, Ana J. García-Sáez, Felix Eichin, Sebastian Herzog, and Tamás Szabó, reflecting a collaborative approach in their research endeavors.

Some of the recent papers produced by Andreas Villunger are:

  • "BCL-2-family protein tBID can act as a BAX-like effector of apoptosis," 2021, The EMBO Journal
  • "Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability," 2021, Translational Psychiatry
  • "Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26," 2020, The EMBO Journal
  • "E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration," 2020, Developmental Cell
  • "SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts," 2020, Molecular Cell

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

    Almut Brand;Katrin Singer;Gudrun E. Koehl;Marlene Kolitzus

  • p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.

    Andreas Villunger;Andreas Villunger;Ewa M. Michalak;Leigh Coultas;Franziska Müllauer

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

    Hamsa Puthalakath;Andreas Villunger;Lorraine A. O'Reilly;Jennifer G. Beaumont

  • FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

    Han You;Marc Pellegrini;Marc Pellegrini;Katsuya Tsuchihara;Katsuya Tsuchihara;Kazuo Yamamoto;Kazuo Yamamoto

  • Bcl2 family proteins in carcinogenesis and the treatment of cancer.

    Anna Frenzel;Francesca Grespi;Waldemar Chmelewskij;Andreas Villunger

  • Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

    Junya Kuroda;Hamsa Puthalakath;Mark S. Cragg;Priscilla N. Kelly;Priscilla N. Kelly

  • Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL

    David C. S. Huang;Michael Hahne;Michael Schroeter;Karl Frei

  • Signalling strength determines proapoptotic functions of STING

    Muhammet F. Gulen;Ute Koch;Simone M. Haag;Fabian Schuler

  • Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

    Ting Ting Tan;Kurt Degenhardt;Kurt Degenhardt;Deirdre A. Nelson;Brian Beaudoin

  • BH3-only proteins Puma and Bim are rate-limiting for γ-radiation– and glucocorticoid-induced apoptosis of lymphoid cells in vivo

    Miriam Erlacher;Miriam Erlacher;Ewa M. Michalak;Ewa M. Michalak;Priscilla N. Kelly;Priscilla N. Kelly;Verena Labi;Verena Labi

  • Noxa: at the tip of the balance between life and death.

    C Ploner;R Kofler;A Villunger

  • Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

    Espen Melum;Andre Franke;Christoph Schramm;Tobias J Weismüller

  • Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

    Miriam Erlacher;Verena Labi;Claudia Manzl;Günther Böck

  • Drug-induced Apoptosis Is Associated with Enhanced Fas (Apo-1/CD95) Ligand Expression but Occurs Independently of Fas (Apo-1/CD95) Signaling in Human T-Acute Lymphatic Leukemia Cells

    Andreas Villunger;Alexander Egle;Marion Kos;Bernd L. Hartmann

  • p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

    David Teis;Nicole Taub;Robert Kurzbauer;Diana Hilber

  • In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute.

    E M Michalak;A Villunger;A Villunger;J M Adams;A Strasser

  • How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?

    A Olsson;C Manzl;A Strasser;A Villunger

  • BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.

    V Labi;M Erlacher;S Kiessling;A Villunger

Frequent Co-Authors

Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Georg Häcker
Georg Häcker University of Freiburg
Philippe Bouillet
Philippe Bouillet Walter and Eliza Hall Institute of Medical Research
Marco J. Herold
Marco J. Herold Walter and Eliza Hall Institute of Medical Research
Jerry M. Adams
Jerry M. Adams Walter and Eliza Hall Institute of Medical Research
Gottfried Baier
Gottfried Baier Innsbruck Medical University
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Marc Pellegrini
Marc Pellegrini Walter and Eliza Hall Institute of Medical Research
Richard Greil
Richard Greil Paracelsus Medical University
Charlotte M. Niemeyer
Charlotte M. Niemeyer University of Freiburg

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