Georg Häcker

Overview

Best Publications

• Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

  Hans Häcker;Vanessa Redecke;Blagoy Blagoev;Irina Kratchmarova

  1298
  Citations

• cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

  Maria Feoktistova;Maria Feoktistova;Peter Geserick;Peter Geserick;Beate Kellert;Diana Panayotova Dimitrova

  1188
  Citations

• The morphology of apoptosis.

  Georg Häcker

  1090
  Citations

• Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

  James E. Vince;W. Wei Lynn Wong;W. Wei Lynn Wong;Ian Gentle;Kate E. Lawlor;Kate E. Lawlor

  561
  Citations

• FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

  Han You;Marc Pellegrini;Marc Pellegrini;Katsuya Tsuchihara;Katsuya Tsuchihara;Kazuo Yamamoto;Kazuo Yamamoto

  522
  Citations

• Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells

  Robert Besch;Hendrik Poeck;Tobias Hohenauer;Daniela Senft

  519
  Citations

• 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

  Poeck H;Besch R;Maihoefer C;Maihoefer C;Renn M

  463
  Citations

• NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP

  Sebastian Kreuz;Daniela Siegmund;Jost-Julian Rumpf;Dierk Samel

  315
  Citations

• Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage

  Lukas Schwab;Luise Goroncy;Senthilnathan Palaniyandi;Sanjivan Gautam

  315
  Citations

• Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

  Nimitha R Mathew;Nimitha R Mathew;Francis Baumgartner;Lukas Braun;David O'Sullivan

  298
  Citations

• Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

  Miriam Erlacher;Verena Labi;Claudia Manzl;Günther Böck

  272
  Citations

• Chlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteins.

  Silke F. Fischer;Juliane Vier;Susanne Kirschnek;Andreas Klos

  264
  Citations

• Signaling of Apoptosis through TLRs Critically Involves Toll/IL-1 Receptor Domain-Containing Adapter Inducing IFN-β, but Not MyD88, in Bacteria-Infected Murine Macrophages

  Klaus Ruckdeschel;Gudrun Pfaffinger;Rudolf Haase;Andreas Sing

  244
  Citations

• Tryptophan deprivation induces inhibitory receptors ILT3 and ILT4 on dendritic cells favoring the induction of human CD4+CD25+ Foxp3+ T regulatory cells.

  Manuela Brenk;Marina Scheler;Susanne Koch;Jürgen Neumann

  230
  Citations

• Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.

  L A O'Reilly;P Ekert;N Harvey;V Marsden

  218
  Citations

• Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis.

  Uwe Koedel;Tobias Frankenberg;Susanne Kirschnek;Bianca Obermaier

  218
  Citations

• Activation of the immune system by bacterial CpG-DNA.

  Georg Häcker;Vanessa Redecke;Hans Häcker

  196
  Citations

• Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells.

  Hans Häcker;Harald Mischak;Georg Häcker;Sema Eser

  182
  Citations

• Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells.

  A Weber;Z Kirejczyk;R Besch;S Potthoff

  173
  Citations

• Characterization of Antiapoptotic Activities of Chlamydia pneumoniae in Human Cells

  Silke F. Fischer;Claudia Schwarz;Juliane Vier;Georg Häcker

  169
  Citations