D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 12,408 145 World Ranking 9081 National Ranking 674

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Apoptosis
  • Immune system

His scientific interests lie mostly in Cell biology, Apoptosis, Signal transduction, Programmed cell death and Molecular biology. The Cell biology study combines topics in areas such as Cytokine, Puma, Caspase, Caspase 8 and Caspase 1. His Apoptosis study integrates concerns from other disciplines, such as Chlamydia trachomatis, Kinase, Transfection and Interferon type I.

His Signal transduction research integrates issues from Cancer research and TRIF. Georg Häcker does research in Programmed cell death, focusing on Ripoptosome specifically. His Molecular biology research is multidisciplinary, relying on both Cytotoxic T cell, Apoptotic DNA fragmentation and T cell, Thymocyte.

His most cited work include:

  • Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 (771 citations)
  • cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms (632 citations)
  • The morphology of apoptosis. (563 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Apoptosis, Programmed cell death, Immunology and Molecular biology. His work carried out in the field of Cell biology brings together such families of science as T cell and Chlamydia trachomatis. His work deals with themes such as Cell, Cell culture and Immune system, which intersect with Apoptosis.

His studies deal with areas such as Cancer research, Downregulation and upregulation and Virology as well as Cell culture. His Programmed cell death research incorporates elements of Necrosis, Phagocytosis, Cellular differentiation and Bacteria. His work in Signal transduction tackles topics such as Caspase 8 which are related to areas like FADD and Inhibitor of apoptosis.

He most often published in these fields:

  • Cell biology (61.59%)
  • Apoptosis (45.12%)
  • Programmed cell death (26.83%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (61.59%)
  • Apoptosis (45.12%)
  • Chlamydia (4.88%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Apoptosis, Chlamydia, Immunology and Microbiology. His studies examine the connections between Cell biology and genetics, as well as such issues in Programmed cell death, with regards to Intracellular. Georg Häcker interconnects Progenitor cell, Mitosis, DNA damage and Function in the investigation of issues within Apoptosis.

His Chlamydia research incorporates themes from Cell autonomous, Chlamydia trachomatis and Protein biosynthesis. His studies deal with areas such as Tuberculosis, Mycobacterium tuberculosis and Candidate gene as well as Immunology. His Microbiology study combines topics in areas such as Inflammation, Antibody and Intestinal mucosa.

Between 2017 and 2021, his most popular works were:

  • Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells (99 citations)
  • Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset (35 citations)
  • A non‐death function of the mitochondrial apoptosis apparatus in immunity (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Apoptosis
  • Immune system

His primary areas of study are Cancer research, Immune system, Function, Apoptosis and Immunology. Georg Häcker interconnects XIAP, NOD2, Pattern recognition receptor, XIAP Deficiency and Mitophagy in the investigation of issues within Cancer research. Georg Häcker combines subjects such as Cell, Chlamydia trachomatis, Signalling pathways and Epithelium with his study of Immune system.

The various areas that Georg Häcker examines in his Function study include Secretion, Cytokine secretion, Immunity and Apoptotic signaling pathway. His work deals with themes such as Programmed cell death and Intracellular, Cell biology, which intersect with Secretion. As part of his studies on Cell biology, he often connects relevant subjects like Lysis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

Hans Häcker;Vanessa Redecke;Blagoy Blagoev;Irina Kratchmarova.
Nature (2006)

1105 Citations

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

Maria Feoktistova;Maria Feoktistova;Peter Geserick;Peter Geserick;Beate Kellert;Diana Panayotova Dimitrova.
Molecular Cell (2011)

992 Citations

The morphology of apoptosis.

Georg Häcker.
Cell and Tissue Research (2000)

869 Citations

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

Han You;Marc Pellegrini;Marc Pellegrini;Katsuya Tsuchihara;Katsuya Tsuchihara;Kazuo Yamamoto;Kazuo Yamamoto.
Journal of Experimental Medicine (2006)

462 Citations

Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation

James E. Vince;W. Wei Lynn Wong;W. Wei Lynn Wong;Ian Gentle;Kate E. Lawlor;Kate E. Lawlor.
Immunity (2012)

438 Citations

Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells

Robert Besch;Hendrik Poeck;Tobias Hohenauer;Daniela Senft.
Journal of Clinical Investigation (2009)

408 Citations

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

Hendrik Poeck;Hendrik Poeck;Hendrik Poeck;Robert Besch;Cornelius Maihoefer;Cornelius Maihoefer;Marcel Renn.
Nature Medicine (2008)

384 Citations

NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP

Sebastian Kreuz;Daniela Siegmund;Jost-Julian Rumpf;Dierk Samel.
Journal of Cell Biology (2004)

282 Citations

Chlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteins.

Silke F. Fischer;Juliane Vier;Susanne Kirschnek;Andreas Klos.
Journal of Experimental Medicine (2004)

260 Citations

Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

Miriam Erlacher;Verena Labi;Claudia Manzl;Günther Böck.
Journal of Experimental Medicine (2006)

240 Citations

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