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Biology and Biochemistry

D-Index
71
Citations
18098
World Ranking
6645
National Ranking
3090

Overview

Samuel D. Rabkin is affiliated with Harvard University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work focuses significantly on virus-based gene therapy, herpesvirus infections and treatments, CAR-T cell therapy, cancer research, and glioma diagnosis and treatment. The scientist's publications also touch on viral infectious diseases and gene expression in insects, as well as viral gastroenteritis research and epidemiology.

The main fields of study represented in their research include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields within their research activity span:

  • Genetics
  • Epidemiology
  • Oncology
  • Molecular Biology
  • Biotechnology

The primary topics of their work comprise:

  • Virus-based gene therapy research
  • Herpesvirus Infections and Treatments
  • CAR-T cell therapy research
  • Cancer Research and Treatments
  • Viral Infectious Diseases and Gene Expression in Insects
  • Glioma Diagnosis and Treatment
  • Viral gastroenteritis research and epidemiology

Among frequent coauthors collaborating with Samuel D. Rabkin are Hiroaki Wakimoto, Robert L. Martuza, Dipongkor Saha, Howard L. Kaufman, and Judit Sánchez Gil.

Samuel D. Rabkin's work appears frequently in several scientific journals. The most common publication venues include:

  • Neuro-Oncology
  • Journal for ImmunoTherapy of Cancer
  • Journal of Visualized Experiments
  • Clinical Cancer Research
  • Expert Opinion on Drug Discovery

Selected recent papers authored or coauthored by Samuel D. Rabkin include:

  • Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma, 2020, Clinical Cancer Research
  • Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma, 2020, Journal for ImmunoTherapy of Cancer
  • Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma, 2020, Acta Neuropathologica Communications
  • The discovery and development of oncolytic viruses: are they the future of cancer immunotherapy?, 2020, Expert Opinion on Drug Discovery
  • Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival, 2024, Journal for ImmunoTherapy of Cancer

Best Publications

  • Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial.

    J M Markert;M D Medlock;S D Rabkin;G Y Gillespie

  • Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas

    Toshihiro Mineta;Samuel D. Rabkin;Takahito Yazaki;William D. Hunter

  • Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

    Mario Luca Suva;Mario Luca Suva;Mario Luca Suva;Esther Rheinbay;Esther Rheinbay;Esther Rheinbay;Shawn M. Gillespie;Shawn M. Gillespie;Shawn M. Gillespie;Anoop Premswaroop Patel;Anoop Premswaroop Patel

  • Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing.

    Tomoki Todo;Robert L. Martuza;Samuel D. Rabkin;Paul A. Johnson

  • Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade

    Dipongkor Saha;Robert L. Martuza;Samuel D. Rabkin

  • Oncolytic Viruses and Their Application to Cancer Immunotherapy

    Chiocca Ea;Rabkin Sd

  • Human Glioblastoma–Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

    Hiroaki Wakimoto;Santosh Kesari;Christopher J. Farrell;William T. Curry

  • Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity.

    Masahiro Toda;Samuel D. Rabkin;Hidefumi Kojima;Robert L. Martuza

  • Oncolytic herpes simplex virus vectors for cancer virotherapy

    Susan Varghese;Samuel D Rabkin

  • Treatment of Malignant Gliomas Using Ganciclovir-hypersensitive, Ribonucleotide Reductase-deficient Herpes Simplex Viral Mutant'

    Toshihiro Mineta;Samuel D. Rabkin;Robert L. Martuza

  • An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma

    Esther Rheinbay;Mario L. Suvà;Mario L. Suvà;Mario L. Suvà;Shawn M. Gillespie;Shawn M. Gillespie;Shawn M. Gillespie;Hiroaki Wakimoto

  • Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells

    Hiroaki Wakimoto;Gayatry Mohapatra;Ryuichi Kanai;William T. Curry

  • Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation of Intracerebral Injection in Nonhuman Primates

    William D. Hunter;Robert L. Martuza;Frank Feigenbaum;Tomoki Todo

  • Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus.

    Tomoki Todo;Samuel D. Rabkin;Periasamy Sundaresan;Aiguo Wu

  • In Situ Cancer Vaccination: An IL-12 Defective Vector/Replication-Competent Herpes Simplex Virus Combination Induces Local and Systemic Antitumor Activity

    Masahiro Toda;Robert L. Martuza;Hidefumi Kojima;Samuel D. Rabkin

  • Preproenkephalin promoter yields region-specific and long-term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector.

    M G Kaplitt;A D Kwong;S P Kleopoulos;C V Mobbs

  • Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model.

    Tooba A. Cheema;Hiroaki Wakimoto;Peter E. Fecci;Jianfang Ning

  • Treatment of Human Malignant Meningiomas by G207, a Replication-competent Multimutated Herpes Simplex Virus 1

    Takahito Yazaki;Herbert J. Manz;Samuel D. Rabkin;Robert L. Martuza

  • Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1

    Masahiro Toda;Samuel D. Rabkin;Robert L. Martuza

  • Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

    Mario L. Suvà;Esther Rheinbay;Shawn M. Gillespie;Anoop P. Patel

Frequent Co-Authors

Robert L. Martuza
Robert L. Martuza Harvard Medical School
Tomoki Todo
Tomoki Todo University of Tokyo
Donald W. Pfaff
Donald W. Pfaff Rockefeller University
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute
Khalid Shah
Khalid Shah Brigham and Women's Hospital
David N. Louis
David N. Louis Harvard University
Luc Jasmin
Luc Jasmin University of California, San Francisco
Yechiel Becker
Yechiel Becker Hebrew University of Jerusalem
Miguel Rivera
Miguel Rivera Harvard University
Aviv Regev
Aviv Regev Genentech

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