Lorraine A. O'Reilly

Overview

Best Publications

• ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

  Hamsa Puthalakath;Lorraine A. O'Reilly;Priscilla Gunn;Lily Lee

  1678
  Citations

• Bim: a novel member of the Bcl-2 family that promotes apoptosis

  Liam O'Connor;Andreas Strasser;Lorraine A. O'Reilly;George Hausmann

  1466
  Citations

• The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex

  Hamsa Puthalakath;David C.S Huang;Lorraine A O’Reilly;Stephen M King

  1448
  Citations

• Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

  Hamsa Puthalakath;Andreas Villunger;Lorraine A. O'Reilly;Jennifer G. Beaumont

  819
  Citations

• Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

  Vanessa S. Marsden;Liam O'Connor;Liam O'Connor;Lorraine A. O'Reilly;John Silke

  722
  Citations

• Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

  Eugene Maraskovsky;Lorraine A O'Reilly;Mark Teepe;Lynn M Corcoran

  617
  Citations

• Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

  James E. Vince;W. Wei Lynn Wong;W. Wei Lynn Wong;Ian Gentle;Kate E. Lawlor;Kate E. Lawlor

  561
  Citations

• Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain.

  Torben Lund;Lorraine O'Reilly;Patricia Hutchings;Osami Kanagawa

  477
  Citations

• The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry.

  L. A. O'reilly;D. C. S. Huang;A. Strasser

  457
  Citations

• The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

  David C.S. Huang;Lorraine A. O'Reilly;Andreas Strasser;Suzanne Cory

  412
  Citations

• The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

  Jian Guo Zhang;Jian Guo Zhang;Peter E. Czabotar;Peter E. Czabotar;Antonia N. Policheni;Antonia N. Policheni;Irina Caminschi;Irina Caminschi;Irina Caminschi

  404
  Citations

• B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells

  Raelene J. Grumont;Ian J. Rourke;Lorraine A. O'Reilly;Andreas Strasser

  359
  Citations

• Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

  Simone Marianne Schoenwaelder;Yu-Ping Yuan;Emma C Josefsson;Michael J White

  344
  Citations

• Novel Mechanisms of Apoptosis Induced by Histone Deacetylase Inhibitors

  Melissa J Peart;Kellie M Tainton;Astrid A Ruefli;Anthony E Dear

  320
  Citations

• Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages.

  Patricia Hutchings;Hugh Rosen;Lorraine O'Reilly;Elizabeth Simpson

  313
  Citations

• bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells.

  Kenneth G.C. Smith;Amanda Light;Lorraine A. O'Reilly;Soon-Meng Ang

  312
  Citations

• A type III effector antagonizes death receptor signalling during bacterial gut infection

  Jaclyn S Pearson;Cristina Giogha;Sze Ying Ong;Catherine Lydia Kennedy

  301
  Citations

• The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells.

  Lorraine A. O’Reilly;Leonie Cullen;Jane Visvader;Jane Visvader;Geoffrey J. Lindeman;Geoffrey J. Lindeman

  299
  Citations

• The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.

  Mathis Grossmann;Lorraine A. O'Reilly;Raffi Gugasyan;Andreas Strasser

  274
  Citations

• CD95, BIM and T cell homeostasis

  Philippe Bouillet;Lorraine A O'Reilly

  262
  Citations