John H.J. Petrini

Overview

Best Publications

• The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.

  James P Carney;James P Carney;Richard S Maser;Heidi Olivares;Elizabeth M Davis

  1490
  Citations

• The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder

  Grant S Stewart;Richard S Maser;Tanja Stankovic;Debra A Bressan

  1245
  Citations

• ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

  Dae-Sik Lim;Seong-Tae Kim;Bo Xu;Richard S. Maser

  1016
  Citations

• The MRE11 complex: starting from the ends

  Travis H. Stracker;John H. J. Petrini

  815
  Citations

• Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres.

  X.-D. Zhu;B. Küster;M. Mann;J. H. J. Petrini

  785
  Citations

• The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

  Karl Peter Hopfner;Lisa Craig;Gabriel Moncalian;Robert A. Zinkel

  696
  Citations

• hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.

  R. S. Maser;K. J. Monsen;B. E. Nelms;J. H. J. Petrini

  672
  Citations

• Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break

  Robert Shroff;Ayelet Arbel-Eden;Duane Pilch;Grzegorz Ira

  639
  Citations

• In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts

  Benjamin E. Nelms;Richard S. Maser;James F. MacKay;Max G. Lagally

  621
  Citations

• Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.

  Courtney A. Lovejoy;Wendi Li;Steven Reisenweber;Supawat Thongthip

  617
  Citations

• The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways.

  Jacob Falck;John H.J. Petrini;Bret R. Williams;Jiri Lukas

  526
  Citations

• Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

  Guangbin Luo;Michelle S. Yao;Carla F. Bender;Michael Mills

  508
  Citations

• DNA damage-dependent nuclear dynamics of the Mre11 complex.

  Olga K. Mirzoeva;John H. J. Petrini

  506
  Citations

• A DNA damage response pathway controlled by Tel1 and the Mre11 complex.

  Takehiko Usui;Takehiko Usui;Hideyuki Ogawa;Hideyuki Ogawa;John H.J Petrini

  484
  Citations

• The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.

  Jan Karlseder;Kristina Hoke;Olga K Mirzoeva;Christopher Bakkenist

  470
  Citations

• The cellular response to DNA double-strand breaks: defining the sensors and mediators.

  John H.J Petrini;Travis H Stracker

  470
  Citations

• The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia.

  Orna Levran;Claire Attwooll;Rashida T Henry;Kelly L Milton

  465
  Citations

• The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae.

  Debra A. Bressan;Bonnie K. Baxter;John H. J. Petrini

  361
  Citations

• The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together.

  Travis H. Stracker;Jan-Willem F. Theunissen;Monica Morales;John H.J. Petrini

  338
  Citations

• Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.

  G. M. Dolganov;R. S. Maser;A. Novikov;L. Tosto

  315
  Citations