World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
22423
World Ranking
3371
National Ranking
1695

Medicine

D-Index
85
Citations
23061
World Ranking
14732
National Ranking
7453

Overview

David Roth is affiliated with the University of Miami in the United States and has contributed extensively to the field of Medicine, focusing primarily on hepatology, transplantation, epidemiology, nephrology, and infectious diseases. Their body of work encompasses significant research on renal transplantation outcomes and treatments, hepatitis C virus research, renal diseases and glomerulopathies, liver disease and transplantation, pregnancy and medication impact, hepatitis B virus studies, and tuberculosis research and epidemiology.

Their notable recent papers include:

  • "KDOQI US Commentary on the 2018 KDIGO Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C" (2020), published in American Journal of Kidney Diseases
  • "Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings" (2020), published in Nature Medicine
  • "Benefit of B7-1 staining and abatacept for treatment-resistant post-transplant focal segmental glomerulosclerosis in a predominantly pediatric cohort: time for a reappraisal" (2022), published in Pediatric Nephrology
  • "The podocyte: glomerular sentinel at the crossroads of innate and adaptive immunity" (2023), published in Frontiers in Immunology
  • "Randomized trial of 3 maintenance regimens (TAC/SRL vs. TAC/MMF vs. CSA/SRL) with low-dose corticosteroids in primary kidney transplantation: 18-year results" (2020), published in Clinical Transplantation

Frequent co-authors collaborating with David Roth include George W. Burke, Gaetano Ciancio, Warren Kupin, Mariella Ortigosa-Goggins, and Adela Mattiazzi.

They have published multiple works across prominent venues such as Frontiers in Immunology, Clinical Transplantation, American Journal of Kidney Diseases, Kidney International Reports, and Nature Medicine.

David Roth's research interests span several subfields with a strong focus on hepatology and transplantation, which are reflected in their extensive publication record. Their studies cover critical issues in renal transplantation outcomes, hepatitis viruses, and immune mechanisms relevant to kidney disease and transplantation medicine.

Best Publications

  • Sequential therapies for proliferative lupus nephritis

    Gabriel Contreras;Victoriano Pardo;Baudouin Leclercq;Oliver Lenz

  • Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

    Changli Wei;Shafic El Hindi;Jing Li;Alessia Fornoni

  • Grazoprevir plus elbasvir in treatment-naive and treatment-experienced patients with hepatitis C virus genotype 1 infection and stage 4-5 chronic kidney disease (the C-SURFER study): a combination phase 3 study.

    David Roth;David R. Nelson;Annette Bruchfeld;Annmarie Liapakis

  • V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes.

    David B. Roth;Joseph P. Menetski;Pamela B. Nakajima;Melvin J. Bosma

  • Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction.

    D B Roth;J H Wilson

  • Growth Retardation and Leaky SCID Phenotype of Ku70-Deficient Mice

    Yansong Gu;Katherine J. Seidl;Gary A. Rathbun;Chengming Zhu

  • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

    Chengming Zhu;Molly A. Bogue;Dae Sik Lim;Paul Hasty

  • Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage

    Ludovic Deriano;David B Roth

  • Mechanisms of nonhomologous recombination in mammalian cells.

    D B Roth;T N Porter;J H Wilson

  • Rag mutations reveal robust alternative end joining

    Barbara Corneo;Rebecca L. Wendland;Ludovic Deriano;Xiaoping Cui

  • Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

    Fabrizio d'Adda di Fagagna;M.Prakash Hande;Wei-Min Tong;David Roth

  • Double-strand break repair in Ku86- and XRCC4-deficient cells

    Elena B. Kabotyanski;Larissa Gomelsky;Jung-Ok Han;Thomas D. Stamato

  • RAG Proteins Shepherd Double-Strand Breaks to a Specific Pathway, Suppressing Error-Prone Repair, but RAG Nicking Initiates Homologous Recombination

    Gregory S Lee;Matthew B Neiditch;Sandra S Salus;David B Roth

  • Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

    Mark A. Landree;Jamie A. Wibbenmeyer;David B. Roth

  • Cancer predisposition and hematopoietic failure in Rad50S/S mice

    Carla F. Bender;Michael L. Sikes;Ruth Sullivan;Leslie Erskine Huye

  • A randomized trial of three renal transplant induction antibodies: early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring.

    Gaetano Ciancio;George W. Burke;Jeffrey J. Gaynor;Manuel R. Carreno

  • V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals

    David B. Roth;Pamela B. Nakajima;Joseph P. Menetski;Melvin J. Bosma

  • Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings

    Keith Zucker;Anne Rosen;Alexandra Tsaroucha;Ludmilla de Faria

  • Posttransplant hyperglycemia. Increased incidence in cyclosporine-treated renal allograft recipients.

    David Roth;Martin Milgrom;Violet Esquenazi;Laphalle Fuller

  • The impact of hepatitis C virus infection on renal allograft recipients

    David Roth;Keith Zucker;Robert Cirocco;Angelo M DeMattos

Frequent Co-Authors

Joshua Miller
Joshua Miller Northwestern University
Phillip Ruiz
Phillip Ruiz University of Miami
Andreas G. Tzakis
Andreas G. Tzakis Cleveland Clinic
Camillo Ricordi
Camillo Ricordi University of Miami
Paul J. Martin
Paul J. Martin Fred Hutchinson Cancer Research Center
Martin Gellert
Martin Gellert National Institute of Diabetes and Digestive and Kidney Diseases
Stanislas Pol
Stanislas Pol Université Paris Cité
John H. Wilson
John H. Wilson Baylor College of Medicine
Jay S. Skyler
Jay S. Skyler University of Miami
David R. Nelson
David R. Nelson University of Tennessee Health Science Center

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