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Sathees C. Raghavan

Sathees C. Raghavan

D-Index & Metrics

Molecular Biology

D-Index
48
Citations
8148
World Ranking
2687
National Ranking
7

Overview

Sathees C. Raghavan is a researcher affiliated with the Indian Institute of Science in India, specializing in biochemistry, genetics, and molecular biology. Their publication record comprises 109 works primarily focused on molecular biology and several related subfields, including organic chemistry, cancer research, oncology, and immunology.

The main topics explored in Raghavan's work include:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • PARP inhibition in cancer therapy
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • Carcinogens and Genotoxicity Assessment
  • Cancer therapeutics and mechanisms

Recent papers by Raghavan reflect research on DNA repair and genome editing, among other molecular processes. Notable publications include:

  • "Nonhomologous end joining: new accessory factors fine tune the machinery," 2021, Trends in Genetics
  • "Modulation of DNA double-strand break repair as a strategy to improve precise genome editing," 2020, Oncogene
  • "Characterization of G-quadruplex antibody reveals differential specificity for G4 DNA forms," 2020, DNA Research
  • "MicroRNA miR-29c regulates RAG1 expression and modulates V(D)J recombination during B cell development," 2021, Cell Reports
  • "Characterization of G4 DNA formation in mitochondrial DNA and their potential role in mitochondrial genome instability," 2021, FEBS Journal

Raghavan's publications are frequently found in the following journals:

  • FEBS Journal
  • Biochemical Journal
  • ACS Omega
  • Molecular Carcinogenesis
  • The Journal of Immunology

Collaborations are a significant aspect of Raghavan's research, with frequent coauthors including Bibha Choudhary, Ujjayinee Ray, Séamus J. Martin, Dublin Chair, and Andrey Abramov. These collaborations have contributed to a broad impact across molecular and cancer biology research fields.

Best Publications

  • Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis.

    Shikha Srivastava;Ranganatha R. Somasagara;Mahesh Hegde;Mayilaadumveettil Nishana

  • An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression

    Mrinal Srivastava;Mridula Nambiar;Sheetal Sharma;Subhas S. Karki

  • A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex.

    Sathees C. Raghavan;Patrick C. Swanson;Xlantuo Wu;Chih Lin Hsieh

  • Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for their Lineage and Stage Specificity

    Albert G. Tsai;Haihui Lu;Sathees C. Raghavan;Markus Muschen

  • DNA Double-Strand Break Repair Inhibitors as Cancer Therapeutics

    Mrinal Srivastava;Sathees C. Raghavan

  • Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations.

    Michael R. Lieber;Kefei Yu;Sathees C. Raghavan

  • Chromosomal translocations in cancer

    Mridula Nambiar;Vijayalakshmi Kari;Sathees C. Raghavan

  • Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells

    C.V. Kavitha;Mridula Nambiar;C.S. Ananda Kumar;Bibha Choudhary

  • How does DNA break during chromosomal translocations

    Mridula Nambiar;Sathees C. Raghavan

  • Homology and enzymatic requirements of microhomology-dependent alternative end joining.

    S Sharma;SM Javadekar;M Pandey;M Srivastava

  • Analysis of the V(D)J Recombination Efficiency at Lymphoid Chromosomal Translocation Breakpoints

    Sathees C. Raghavan;Ilan R. Kirsch;Michael R. Lieber

  • Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent anticancer agents

    Subhas S. Karki;Kuppusamy Panjamurthy;Sujeet Kumar;Mridula Nambiar

  • Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma.

    Mridula Nambiar;G. Goldsmith;Balaji T. Moorthy;Michael R. Lieber

  • Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions.

    Satish Kumar Tadi;Robin Sebastian;Sumedha Dahal;Ravi K. Babu

  • Inhibition of nonhomologous end joining to increase the specificity of CRISPR/Cas9 genome editing

    Supriya V. Vartak;Sathees C. Raghavan

  • Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation.

    Sathees C. Raghavan;Paul Chastain;Jeremy S. Lee;Balachandra G. Hegde

  • Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice.

    Ranganatha R. Somasagara;Mahesh Hegde;Kishore K. Chiruvella;Anjaneyulu Musini

  • Synthesis of 2-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid derivatives and evaluation of their cytotoxicity and induction of apoptosis in human leukemia cells.

    S. Chandrappa;C.V. Kavitha;M.S. Shahabuddin;K. Vinaya

  • Phytochemical and Antimicrobial Studies of Methyl Angolensate and Luteolin-7-O-glucoside Isolated from Callus Cultures of Soymida febrifuga.

    Kishore K. Chiruvella;Arifullah Mohammed;Gayathri Dampuri;Rama Gopal Ghanta

  • Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro.

    Sathees C. Raghavan;Patrick C. Swanson;Yunmei Ma;Michael R. Lieber

Frequent Co-Authors

Kanchugarakoppal S. Rangappa
Kanchugarakoppal S. Rangappa University of Mysore
Michael R. Lieber
Michael R. Lieber University of Southern California
Chih-Lin Hsieh
Chih-Lin Hsieh University of Southern California
Erik De Clercq
Erik De Clercq Rega Institute for Medical Research
Avadhesha Surolia
Avadhesha Surolia Indian Institute of Science
Ralf Langen
Ralf Langen University of Southern California
Ilan R. Kirsch
Ilan R. Kirsch Adaptive Biotechnologies (United States)
Markus Müschen
Markus Müschen Yale University
Shantikumar V. Nair
Shantikumar V. Nair Amrita Vishwa Vidyapeetham University

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