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Molecular Biology

D-Index
80
Citations
22690
World Ranking
1001
National Ranking
529

Overview

Ilan R. Kirsch is affiliated with Adaptive Biotechnologies in the United States and has contributed extensively to medical research, particularly in the field of hematology. Their work spans multiple subfields including hematology, oncology, public health, pathology, forensic medicine, and molecular biology, with a primary focus on diseases related to the blood and immune systems.

Key research topics covered by Ilan R. Kirsch include:

  • Acute Lymphoblastic Leukemia research
  • Chronic Lymphocytic Leukemia Research
  • Lymphoma Diagnosis and Treatment
  • Multiple Myeloma Research and Treatments
  • CAR-T cell therapy research
  • Acute Myeloid Leukemia Research
  • Protein Degradation and Inhibitors

They have published extensively in prominent venues with the most frequent publication platforms being:

  • Blood
  • immuneACCESS
  • Clinical Cancer Research
  • Cancer Research
  • Blood Cancer Journal

Some of their recent papers include:

  • "Analytical evaluation of the clonoSEQ Assay for establishing measurable (minimal) residual disease in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple myeloma," 2020, BMC Cancer
  • "Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration," 2021, Clinical Cancer Research
  • "Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection," 2022, JCI Insight
  • "Challenges to Using Big Data in Cancer," 2023, Cancer Research
  • "An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia," 2022, Nature Communications

Frequent collaborators in their research include:

  • Govind Bhagat
  • Rachel E. Rau
  • Karen R. Rabin
  • Meenakshi Devidas
  • Brent L. Wood

Their research reflects a multidisciplinary approach to understanding and treating hematologic malignancies, involving clinical applications as well as molecular and immunological perspectives. The contributions they have made across various cancer research and hematology topics are documented through a significant number of publications and frequent collaborations with other experts in the field.

Best Publications

  • Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

    R Taub;I Kirsch;C Morton;G Lenoir

  • Genetics and Cytogenetics of Multiple Myeloma A Workshop Report

    Rafael Fonseca;Bart Barlogie;Regis Bataille;Christian Bastard

  • L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer.

    Marion M. Nau;Burke J. Brooks;James Battey;Edward Sausville

  • A physical map of the human genome.

    John Douglas Mcpherson;Marco Marra;Marco Marra;La Deana Hillier;Robert H. Waterston

  • t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway

    Giovanni Tonon;Sanjay Modi;Lizi Wu;Akihito Kubo

  • CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial

    Jay Y. Spiegel;Shabnum Patel;Lori Muffly;Nasheed M. Hossain

  • The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.

    C G Begley;P D Aplan;S M Denning;B F Haynes

  • Prognostic and Predictive Roles of High-Degree Microsatellite Instability in Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

    George P. Kim;Linda H. Colangelo;H. Samuel Wieand;Soonmyung Paik

  • Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma.

    Yaping Shou;Maria L. Martelli;Ana Gabrea;Ying Qi

  • Human Immunoglobulin Heavy Chain Genes Map to a Region of Translocations in Malignant B Lymphocytes

    Ilan R. Kirsch;Cynthia C. Morton;Kenneth Nakahara;Philip Leder;Philip Leder

  • Prognostic Value of Thymidylate Synthase, Ki-67, and p53 in Patients With Dukes’ B and C Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

    Carmen J. Allegra;Soon Paik;Linda H. Colangelo;Allyson L. Parr

  • Integration of cytogenetic landmarks into the draft sequence of the human genome

    V. G. Cheung;N. Nowak;W. Jang;I. R. Kirsch

  • Expression of a transfected human c-myc oncogene inhibits differentiation of a mouse erythroleukaemia cell line.

    Ethan Dmitrovsky;W. Michael Kuehl;Gregory F. Hollis;Ilan R. Kirsch

  • Karyotypic Complexity of the NCI-60 Drug-Screening Panel

    Anna V. Roschke;Giovanni Tonon;Kristen S. Gehlhaus;Nicolas McTyre

  • Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity.

    Peter D. Aplan;Donald P. Lombardi;Ann M. Ginsberg;Jeffrey Cossman

  • Distinguishing Right from Left Colon by the Pattern of Gene Expression

    Oleg K. Glebov;Luz M. Rodriguez;Kenneth Nakahara;Jean Jenkins

  • Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript

    C. G. Begley;P. D. Aplan;M. P. Davey;K. Nakahara

  • T-cell receptor gene rearrangements as clinical markers of human T-cell lymphomas.

    Virginia Bertness;Ilan Kirsch;Gregory Hollis;Bruce Johnson

  • Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5'-end predict two translational start sites at two in-frame AUGs.

    N L Shaper;G F Hollis;J G Douglas;I R Kirsch

  • Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells

    Gerard Brady;Filio Billia;Jennifer Knox;Trang Hoang

Frequent Co-Authors

Harlan Robins
Harlan Robins Adaptive Biotechnologies (United States)
Philip Leder
Philip Leder Harvard University
Peter D. Aplan
Peter D. Aplan National Institutes of Health
Thomas Ried
Thomas Ried National Institutes of Health
Cynthia C. Morton
Cynthia C. Morton Brigham and Women's Hospital
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center
Joel H. Shaper
Joel H. Shaper Johns Hopkins University School of Medicine
Carolyn A. Felix
Carolyn A. Felix Children's Hospital of Philadelphia
Adi F. Gazdar
Adi F. Gazdar The University of Texas Southwestern Medical Center

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