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Immunology

D-Index
75
Citations
28137
World Ranking
1956
National Ranking
957

Overview

Harlan Robins is affiliated with Adaptive Biotechnologies in the United States and has a significant body of research primarily focused on immunology, medicine, and microbiology. Their scholarly work spans across multiple subfields, including immunology, infectious diseases, oncology, molecular biology, and genetics.

The scientist's main topics of research cover a broad spectrum of immunological and infectious disease areas. These include SARS-CoV-2 and COVID-19 research, T-cell and B-cell immunology, immune cell function and interaction, COVID-19 clinical research studies, vaccines and immunoinformatics approaches, CAR-T cell therapy research, and immunotherapy and immune responses.

Robins' publications appear predominantly in respected venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Cancer Research, Gastroenterology, and Nature, with bioRxiv hosting the highest number of their papers. Frequent co-authors in their network include Thomas M. Snyder, Rebecca Elyanow, Ian M. Kaplan, Damon May, and Bryan Howie.

Selected recent papers illustrate the scope and focus of Robins' research:

  • Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans (2021, Nature)
  • Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • Comprehensive T cell repertoire characterization of non-small cell lung cancer (2020, Nature Communications)
  • Analytical evaluation of the clonoSEQ Assay for establishing measurable (minimal) residual disease in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple myeloma (2020, BMC Cancer)
  • Fundamental immune-oncogenicity trade-offs define driver mutation fitness (2022, Nature)

Best Publications

  • PD-1 blockade induces responses by inhibiting adaptive immune resistance

    Paul C. Tumeh;Christina L. Harview;Jennifer H. Yearley;I. Peter Shintaku

  • Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells

    Harlan S. Robins;Paulo V. Campregher;Santosh K. Srivastava;Abigail Wacher

  • Using synthetic templates to design an unbiased multiplex PCR assay

    Christopher S. Carlson;Ryan O. Emerson;Anna M. Sherwood;Cindy Desmarais

  • Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire

    Ryan O Emerson;William S DeWitt;Marissa Vignali;Jenna Gravley

  • Overlap and Effective Size of the Human CD8+ T Cell Receptor Repertoire

    Harlan S. Robins;Santosh K. Srivastava;Paulo V. Campregher;Cameron J. Turtle

  • Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

    Douglas B. Johnson;Garrett M. Frampton;Matthew J. Rioth;Erik Yusko

  • CTLA4 blockade broadens the peripheral T cell receptor repertoire

    Lidia Robert;Jennifer Tsoi;Xiaoyan Wang;Ryan O. Emerson

  • Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer

    Sanja Stevanović;Anna Pasetto;Sarah R. Helman;Jared J. Gartner

  • Fractionated Radiation Therapy Stimulates Antitumor Immunity Mediated by Both Resident and Infiltrating Polyclonal T-cell Populations when Combined with PD-1 Blockade.

    Simon J. Dovedi;Eleanor J. Cheadle;Amy L. Popple;Edmund Poon

  • Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis.

    Alexandra Snyder;Alexandra Snyder;Tavi Nathanson;Samuel A. Funt;Samuel A. Funt;Arun Ahuja

  • Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: Implications for latency

    Eain Murphy;Jiří Vaníček;Harlan Robins;Thomas Shenk

  • Immune surveillance by CD8αα + skin-resident T cells in human herpes virus infection

    Jia Zhu;Tao Peng;Tao Peng;Christine Johnston;Khamsone Phasouk

  • Common clonal origin of central and resident memory T cells following skin immunization

    Olivier Gaide;Ryan O Emerson;Xiaodong Jiang;Nicholas Gulati

  • Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans.

    Galit Alter;Galit Alter;Jingyou Yu;Jinyan Liu;Abishek Chandrashekar

  • Immunosequencing: applications of immune repertoire deep sequencing.

    Harlan Robins

  • Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing αβ T cell clones

    Tiago R. Matos;John T. O’Malley;Elizabeth L. Lowry;David Hamm

  • T cell repertoire following autologous stem cell transplantation for multiple sclerosis.

    Paolo A. Muraro;Harlan Robins;Sachin Malhotra;Michael Howell

  • High-Throughput Sequencing Detects Minimal Residual Disease in Acute T Lymphoblastic Leukemia

    David Wu;Anna Sherwood;Jonathan R. Fromm;Stuart S. Winter

  • Novel technologies and emerging biomarkers for personalized cancer immunotherapy.

    Jianda Yuan;Priti S. Hegde;Raphael Clynes;Periklis G. Foukas;Periklis G. Foukas

  • Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions.

    Leonel Maldonado;Jessica E. Teague;Matthew P. Morrow;Iveta Jotova

  • Ultra-sensitive detection of rare T cell clones

    Harlan Robins;Cindy Desmarais;Jessica Matthis;Robert Livingston

  • High-throughput pairing of T cell receptor α and β sequences

    Bryan Howie;Anna M. Sherwood;Ashley D. Berkebile;Jan Berka

Frequent Co-Authors

Christopher S. Carlson
Christopher S. Carlson Fred Hutchinson Cancer Research Center
Mark J. Rieder
Mark J. Rieder University of Washington
Arnold J. Levine
Arnold J. Levine Institute for Advanced Study
Edus H. Warren
Edus H. Warren Fred Hutchinson Cancer Research Center
Thomas S. Kupper
Thomas S. Kupper Brigham and Women's Hospital
Brent L. Wood
Brent L. Wood University of Washington
Rachael A. Clark
Rachael A. Clark Brigham and Women's Hospital
Ilan R. Kirsch
Ilan R. Kirsch Adaptive Biotechnologies (United States)
Nancy L. Haigwood
Nancy L. Haigwood Oregon Health & Science University
James P. Allison
James P. Allison The University of Texas MD Anderson Cancer Center

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