Chih-Lin Hsieh mainly focuses on Molecular biology, DNA methylation, Genetics, DNA and Methyltransferase. Chih-Lin Hsieh has included themes like Superoxide dismutase, SOD1, Chromosome, In vivo and DNA replication in his Molecular biology study. Many of his studies on DNA methylation apply to Methylation as well.
His work in the fields of Exome, Allele frequency and Mutation overlaps with other areas such as Ensemble learning and Overall performance. Chih-Lin Hsieh interconnects Human genome, Breakpoint, Gene, Chromosomal translocation and CpG site in the investigation of issues within DNA. His work is dedicated to discovering how Methyltransferase, Genomic imprinting are connected with Epigenetics and other disciplines.
Chih-Lin Hsieh focuses on Molecular biology, Genetics, DNA, DNA methylation and Gene. His Molecular biology research incorporates elements of Transgene, Biochemistry, Complementary DNA, DNA repair and Gene mapping. In his research, Embryonic stem cell and Cellular differentiation is intimately related to Cell biology, which falls under the overarching field of Genetics.
His study focuses on the intersection of DNA and fields such as Chromosomal translocation with connections in the field of Chromosomal fragile site. The DNA methylation study combines topics in areas such as Methylation and Methyltransferase. He studied Methyltransferase and Genomic imprinting that intersect with Epigenetics.
Chih-Lin Hsieh mostly deals with Genetics, Molecular biology, DNA, DNA methylation and Computational biology. His research ties Bioinformatics and Genetics together. In his work, he performs multidisciplinary research in Molecular biology and RNA silencing.
His DNA research is multidisciplinary, relying on both Chromosomal fragile site, Nuclear gene, Methylated DNA immunoprecipitation and DNA End-Joining Repair. His DNA methylation study incorporates themes from Chromosomal translocation, Footprinting, Chromatin, Methyltransferase and Chromosome Fragile Site. His research integrates issues of Association test, Locus and Cohort in his study of Computational biology.
His primary scientific interests are in Genetics, Molecular biology, Genome-wide association study, Bioinformatics and Familial prostate cancer. He performs integrative study on Genetics and Ensemble learning. His studies in Molecular biology integrate themes in fields like R-loop, Immunoglobulin class switching, Biophysics, Nucleotide and Absolute number.
He has researched Genome-wide association study in several fields, including Prostate cancer, Human genetics, Genetic association and Medical genetics. As part of his studies on Bioinformatics, Chih-Lin Hsieh often connects relevant areas like Family history.
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Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene.
Guo-Liang Xu;Timothy H. Bestor;Déborah Bourc'his;Chih-Lin Hsieh.
Nature (1999)
Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2
Mary Grace Goll;Finn Kirpekar;Keith A. Maggert;Jeffrey A. Yoder.
Science (2006)
Germline Competent Embryonic Stem Cells Derived from Rat Blastocysts
Ping Li;Chang Tong;Ruty Mehrian-Shai;Li Jia.
Cell (2008)
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
Kefei Yu;Frederic Chedin;Chih Lin Hsieh;Thomas E. Wilson.
Nature Immunology (2003)
Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis.
James J. Cali;Chih Lin Hsieh;Chih Lin Hsieh;Uta Francke;Uta Francke;David W. Russell.
Journal of Biological Chemistry (1991)
The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a
Frédéric Chédin;Michael R. Lieber;Chih-Lin Hsieh.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Loss of Imprinting in Colorectal Cancer Linked to Hypomethylation of H19 and IGF2
Hengmi Cui;Patrick Onyango;Sheri Brandenburg;Yiqian Wu.
Cancer Research (2002)
Dependence of transcriptional repression on CpG methylation density.
Chih-Lin Hsieh.
Molecular and Cellular Biology (1994)
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants
Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha.
American Journal of Human Genetics (2016)
A Biochemically Defined System for Mammalian Nonhomologous DNA End Joining
Yunmei Ma;Haihui Lu;Brigette Tippin;Myron F. Goodman.
Molecular Cell (2004)
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