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Genetics

D-Index
59
Citations
10571
World Ranking
3263
National Ranking
1421

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Karen M. Vasquez is affiliated with The University of Texas at Austin in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a notable concentration in Molecular Biology, Cancer Research, Oncology, Ecology, and Clinical Biochemistry.

The main topics covered in their research include DNA Repair Mechanisms, DNA and Nucleic Acid Chemistry, Genomics and Chromatin Dynamics, RNA modifications and cancer, Epigenetics and DNA Methylation, RNA Research and Splicing, and RNA and protein synthesis mechanisms.

Recent publications by Karen M. Vasquez include:

  • Dynamic alternative DNA structures in biology and disease, 2022, Nature Reviews Genetics
  • Distinct DNA repair pathways cause genomic instability at alternative DNA structures, 2020, Nature Communications
  • Long non-coding RNA TINCR as potential biomarker and therapeutic target for cancer, 2020, Life Sciences
  • Targeting Chromosomal Architectural HMGB Proteins Could Be the Next Frontier in Cancer Therapy, 2020, Cancer Research
  • LncRNA ZFAS1 inhibits triple-negative breast cancer by targeting STAT3, 2021, Biochimie

Karen M. Vasquez frequently collaborates with a group of co-authors, including:

  • Guliang Wang
  • Ioannis Mouratidis
  • Nikol Chantzi
  • Ilias Georgakopoulos-Soares
  • Anirban Mukherjee

Their works are commonly published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Research
  • Biochimie
  • Briefings in Bioinformatics

Karen M. Vasquez has been recognized by the American Association for the Advancement of Science (AAAS) as a Fellow since 2014.

Best Publications

  • Non-B DNA structure-induced genetic instability and evolution

    Junhua Zhao;Albino Bacolla;Guliang Wang;Karen M. Vasquez

  • Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity

    Rick Avery Finch;Mao Chin Liu;Susan P. Grill;William C. Rose

  • Manipulating the mammalian genome by homologous recombination

    Karen M. Vasquez;Kathleen Marburger;Zsofia Intody;Zsofia Intody;John H. Wilson

  • DNA triple helices: biological consequences and therapeutic potential.

    Aklank Jain;Guliang Wang;Karen M. Vasquez

  • Specific Mutations Induced by Triplex-Forming Oligonucleotides in Mice

    Karen M. Vasquez;Latha Narayanan;Peter M. Glazer

  • Triplex-directed modification of genes and gene activity

    Karen M. Vasquez;John H. Wilson

  • Non-B DNA structure-induced genetic instability.

    Guliang Wang;Karen M. Vasquez

  • High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage.

    Sabine S. Lange;David L. Mitchell;Karen M. Vasquez

  • DNA fragility in the parallel evolution of pelvic reduction in stickleback fish.

    Kathleen T. Xie;Guliang Wang;Abbey C. Thompson;Julia I. Wucherpfennig

  • Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells

    Guliang Wang;Karen M. Vasquez

  • Z-DNA-forming sequences generate large-scale deletions in mammalian cells

    Guliang Wang;Laura A. Christensen;Karen M. Vasquez

  • HMGB1: The jack-of-all-trades protein is a master DNA repair mechanic

    Sabine S. Lange;Karen M. Vasquez

  • Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability.

    Guliang Wang;Karen M. Vasquez

  • Triplex-forming oligonucleotides: principles and applications.

    Karen M. Vasquez;Peter M. Glazer

  • Critical DNA damage recognition functions of XPC-hHR23B and XPA-RPA in nucleotide excision repair.

    Brian S. Thoma;Karen M. Vasquez

  • In vivo stability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotides

    Joseph G. Zendegui;Karen M. Vasquez;John H. Tinsley;Donald J. Kessler

  • Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells

    Karen M. Vasquez;Gan Wang;Pamela A. Havre;Peter M. Glazer

  • A triplex-forming sequence from the human c-MYC promoter interferes with DNA transcription.

    Boris P. Belotserkovskii;Erandi De Silva;Silvia Tornaletti;Guliang Wang

  • Z-DNA, an active element in the genome.

    Guliang Wang;Karen M Vasquez

  • Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences.

    Albino Bacolla;John A. Tainer;Karen M. Vasquez;David Neil Cooper

Frequent Co-Authors

David Neil Cooper
David Neil Cooper Cardiff University
Peter M. Glazer
Peter M. Glazer Yale University
John H. Wilson
John H. Wilson Baylor College of Medicine
John DiGiovanni
John DiGiovanni The University of Texas at Austin
Howard D. Thames
Howard D. Thames The University of Texas MD Anderson Cancer Center
Theodore G. Wensel
Theodore G. Wensel Baylor College of Medicine
Lei Li
Lei Li The University of Texas MD Anderson Cancer Center
Philip C. Hanawalt
Philip C. Hanawalt Stanford University
Nadia Chuzhanova
Nadia Chuzhanova Nottingham Trent University
Robert M. Stephens
Robert M. Stephens National Institutes of Health

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