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Peter M. Glazer

Peter M. Glazer

D-Index & Metrics

Molecular Biology

D-Index
89
Citations
23869
World Ranking
768
National Ranking
406

Overview

Peter M. Glazer is affiliated with Yale University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, focusing particularly on molecular biology and oncology. The scientist has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a total of 110 publications, and medicine, with 57 publications.

Glazer's subfields of study include molecular biology, oncology, immunology, pulmonary and respiratory medicine, and genetics. The subdiscipline distribution shows a predominant focus on molecular biology with 94 publications, followed by oncology at 21 publications, immunology with 12, pulmonary and respiratory medicine with 8, and genetics with 7.

Their main research topics incorporate areas such as RNA interference and gene delivery, advanced biosensing and bioanalysis techniques, CRISPR and genetic engineering, DNA and nucleic acid chemistry, interferon and immune responses, RNA modifications and cancer, and PARP inhibition in cancer therapy. These topics highlight diverse expertise in gene editing technologies and cancer biology. The number of publications within these topics are as follows:

  • RNA Interference and Gene Delivery: 50
  • Advanced biosensing and bioanalysis techniques: 32
  • CRISPR and Genetic Engineering: 26
  • DNA and Nucleic Acid Chemistry: 18
  • Interferon and immune responses: 16
  • RNA modifications and cancer: 14
  • PARP inhibition in cancer therapy: 12

Recent significant publications by Glazer feature work published between 2020 and 2021 in prominent journals, including:

  • Oncometabolites suppress DNA repair by disrupting local chromatin signalling, 2020, Nature
  • The NIH Somatic Cell Genome Editing program, 2021, Nature
  • Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK Pathway, 2020, Cancer Research
  • Targeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides, 2021, Cells
  • Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair, 2020, Molecules

Frequent co-authors of Glazer include W. Mark Saltzman, Elias Quijano, Ranjit S. Bindra, Alexandra S. Piotrowski-Daspit, and Yanfeng Liu. These collaborations have resulted in repeated joint publications, with the highest count of 21 joint works with W. Mark Saltzman.

The scientist's research is often published in specialized venues, with the most frequent publication venues being:

  • Cancer Research (14 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • NAR Cancer (3 publications)
  • Nature (2 publications)
  • Neuron (2 publications)

Best Publications

  • MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

    Christopher J. Cheng;Raman Bahal;Imran A. Babar;Zachary Pincus

  • Genetic Instability Induced by the Tumor Microenvironment

    Toni Y. Reynolds;Sara Rockwell;Peter M. Glazer

  • MicroRNA Regulation of DNA Repair Gene Expression in Hypoxic Stress

    Meredith E. Crosby;Ritu Kulshreshtha;Mircea Ivan;Peter M. Glazer

  • 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.

    Parker L. Sulkowski;Christopher D. Corso;Nathaniel D. Robinson;Susan E. Scanlon

  • Insulin-like Growth Factor-I Receptor Overexpression Mediates Cellular Radioresistance and Local Breast Cancer Recurrence after Lumpectomy and Radiation

    Bruce C. Turner;Bruce G. Haffty;Latha Narayanan;Jianling Yuan

  • FACILITATING OLIGONUCLEOTIDE DELIVERY : HELPING ANTISENSE DELIVER ON ITS PROMISE

    Alan M. Gewirtz;Cy A. Stein;Peter M. Glazer

  • Mutagenesis in Mammalian Cells Induced by Triple Helix Formation and Transcription-Coupled Repair

    Gan Wang;Michael M. Seidman;Peter M. Glazer

  • Down-Regulation of Rad51 and Decreased Homologous Recombination in Hypoxic Cancer Cells

    Ranjit S. Bindra;Paul J. Schaffer;Alice Meng;Jennifer Woo

  • Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status

    Bruce G Haffty;Elizabeth Harrold;Atif J Khan;Pradip Pathare

  • Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

    Ranjit S. Bindra;Shannon L. Gibson;Alice Meng;Ulrica Westermark

  • Chronic Hypoxia Decreases Synthesis of Homologous Recombination Proteins to Offset Chemoresistance and Radioresistance

    Norman Chan;Marianne Koritzinsky;Helen Zhao;Helen Zhao;Ranjit Bindra

  • MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

    Elena Favaro;Elena Favaro;Anassuya Ramachandran;Robert McCormick;Harriet Gee

  • Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.

    Valia T. Mihaylova;Ranjit S. Bindra;Jianling Yuan;Denise Campisi

  • Triplex DNA: fundamentals, advances, and potential applications for gene therapy

    Phillip P. Chan;P. M. Glazer

  • Specific Mutations Induced by Triplex-Forming Oligonucleotides in Mice

    Karen M. Vasquez;Latha Narayanan;Peter M. Glazer

  • Targeted Mutagenesis in Mammalian Cells Mediated by Intracellular Triple Helix Formation

    Gan Wang;D. D. Levy;M. M. Seidman;P. M. Glazer

  • p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells.

    Pamela A. Havre;Jianling Yuan;Lora Hedrick;Kathleen R. Cho

  • Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH

    Jianling Yuan;Latha Narayanan;Sara Rockwell;Peter M. Glazer

  • Targeted gene knockout mediated by triple helix forming oligonucleotides.

    A. Majumdar;A. Khorlin;N. Dyatkina;F.-L. M. Lin

  • Triplex forming oligonucleotides: sequence-specific tools for gene targeting

    Melissa P. Knauert;Peter M. Glazer

Frequent Co-Authors

W. Mark Saltzman
W. Mark Saltzman Yale University
Bruce G. Haffty
Bruce G. Haffty Rutgers, The State University of New Jersey
Michael M. Seidman
Michael M. Seidman National Institutes of Health
Robert G. Bristow
Robert G. Bristow University of Manchester
Karen M. Vasquez
Karen M. Vasquez The University of Texas at Austin
R. Michael Liskay
R. Michael Liskay Oregon Health & Science University
Donald M. Engelman
Donald M. Engelman Yale University
Frank J. Slack
Frank J. Slack Beth Israel Deaconess Medical Center
Tian Xu
Tian Xu Westlake University
Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio

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