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D-Index & Metrics

Molecular Biology

D-Index
53
Citations
7773
World Ranking
2400
National Ranking
1184

Overview

Eric B. Kmiec is affiliated with the University of Delaware in the United States. Their research centers primarily on biochemistry, genetics, and molecular biology, with particular contributions to molecular biology and genetics. Other subfields include oncology, plant science, and business and international management.

The scientist's research topics encompass several key areas, including:

  • CRISPR and genetic engineering
  • Virus-based gene therapy research
  • RNA and protein synthesis mechanisms
  • CAR-T cell therapy research
  • Pluripotent stem cells research
  • Advanced biosensing and bioanalysis techniques
  • Innovation and socioeconomic development

Kmiec has authored numerous papers, with recent publications highlighting work in gene editing, DNA repair, and cancer research. Selected papers include:

  • "Deconvolution of Complex DNA Repair (DECODR): Establishing a Novel Deconvolution Algorithm for Comprehensive Analysis of CRISPR-Edited Sanger Sequencing Data," 2021, The CRISPR Journal
  • "Kinetics of Nuclear Uptake and Site-Specific DNA Cleavage during CRISPR-Directed Gene Editing in Solid Tumor Cells," 2020, Molecular Cancer Research
  • "Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth," 2022, Proceedings of the National Academy of Sciences
  • "gRNA Sequence Heterology Tolerance Catalyzed by CRISPR/Cas in an In Vitro Homology-Directed Repair Reaction," 2020, Molecular Therapy - Nucleic Acids
  • "Modeling pediatric AML FLT3 mutations using CRISPR/Cas12a- mediated gene editing," 2020, Leukemia & lymphoma/Leukemia and lymphoma

The scientist frequently publishes in venues such as:

  • Molecular Therapy - Nucleic Acids
  • The CRISPR Journal
  • Gene and Genome Editing
  • Gene
  • Molecular Cancer Research

Collaboration is a significant aspect of their work. Frequent coauthors include Brett M. Sansbury, Kelly Banas, Pawel Bialk, Natalia Rivera-Torres, and Amanda M. Hewes.

Best Publications

  • Correction of the Mutation Responsible for Sickle Cell Anemia by an RNA-DNA Oligonucleotide

    Allyson Cole-Strauss;Kyonggeun Yoon;Yufei Xiang;Bruce C. Byrne

  • Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide

    Kyonggeun Yoon;Allyson Cole-Strauss;Eric B. Kmiec

  • Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background.

    Zhigang Shu;Sheryl Smith;Lijuan Wang;Michael C. Rice

  • Beta protein of bacteriophage lambda promotes renaturation of DNA.

    E Kmiec;W K Holloman

  • Nucleic acid of a chimeric repair vector and use in repairing cell mutations

    Kmiec Eric B;Cole-Strauss Allyson;Yoon Kyonggeun

  • The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts

    Howard B. Gamper;Hetal Parekh;Michael C. Rice;Michael Bruner

  • Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract

    Allyson Cole-Strauss;Howard Gamper;Madeline Muñoz;Nikki Cheng

  • Targeted Nucleotide Exchange in the Alkaline Phosphatase Gene of HuH-7 Cells Mediated by a Chimeric RNA/DNA Oligonucleotide

    Betsy T. Kren;Allyson Cole-Strauss;Eric B. Kmiec;Clifford J. Steer

  • CHIMERA MUTATION VECTOR HAVING NON-NATURAL NUCLEOTIDE

    Kimec Eric B

  • A plausible mechanism for gene correction by chimeric oligonucleotides.

    Howard B. Gamper;Allyson Cole-Strauss;Richard Metz;Hetal Parekh

  • Homologous pairing of DNA molecules by ustilago rec1 protein is promoted by sequences of Z-DNA

    Eric B. Kmiec;William K. Holloman

  • Homologous pairing of DNA molecules promoted by a protein from ustilago

    Eric Kmiec;William K. Holloman

  • Targeted chromosomal genomic alterations with modified single stranded oligonucleotides

    Eric B. Kmiec;Howard B. Gamper;Michael C. Rice

  • In vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides

    Li Liu;Michael C. Rice;Eric B. Kmiec

  • Synapsis promoted by ustilago rec1 protein

    Eric B. Kmiec;William K. Holloman

  • Gene therapy progress and prospects: targeted gene repair.

    H Parekh-Olmedo;L Ferrara;L Ferrara;E Brachman;E Brachman;E B Kmiec

  • Left-Handed DNA and the Synaptic Pairing Reaction Promoted by Ustilago Recl Protein

    Eric B. Kmiec;Kimon J. Angelides;William K. Holloman

  • Isolation of Human and Mouse Genes Based on Homology to REC2, a Recombinational Repair Gene From the Fungus Ustilago Maydis

    Michael C. Rice;Sheryl T. Smith;Florencia Bullrich;Pamela Havre

  • Cell-free chimeraplasty and fukaryotic use of heteroduplex mutational vector

    Kmiec E B;Gamper H B;Cole-Strauss A D

  • DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates.

    Jennifer Illuzzi;Sarah Yerkes;Hetal Parekh-Olmedo;Eric B. Kmiec

Frequent Co-Authors

Clifford J. Steer
Clifford J. Steer University of Minnesota
Kirk J. Czymmek
Kirk J. Czymmek Donald Danforth Plant Science Center
John F. Engelhardt
John F. Engelhardt University of Iowa
Ziying Yan
Ziying Yan University of Iowa
Jeffrey M. Becker
Jeffrey M. Becker University of Tennessee at Knoxville
James F. Gusella
James F. Gusella Harvard University
Dimitri Krainc
Dimitri Krainc Northwestern University
Gerald Litwack
Gerald Litwack Texas A&M Health Science Center
Robin Holliday
Robin Holliday Commonwealth Scientific and Industrial Research Organisation
David R. Corey
David R. Corey The University of Texas Southwestern Medical Center

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