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Biology and Biochemistry

D-Index
86
Citations
21855
World Ranking
3035
National Ranking
1541

Overview

Clifford J. Steer is affiliated with the University of Minnesota in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, and medicine, with an emphasis on molecular biology, cancer research, surgery, infectious diseases, and hepatology.

The scientist's main areas of study include:

  • MicroRNA in disease regulation
  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • Liver physiology and pathology
  • Virus-based gene therapy research
  • Cancer-related molecular mechanisms research
  • SARS-CoV-2 and COVID-19 Research

Clifford J. Steer has contributed to a range of research published in various venues. The most frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Hepatic Medicine Evidence and Research
  • Genes
  • Cell Transplantation
  • PLoS ONE

Notable recent papers authored or coauthored by the scientist are:

  • MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication Between Kupffer Cells and Regulatory T Cells, 2021, Gastroenterology
  • MicroRNA-206 promotes the recruitment of CD8+ T cells by driving M1 polarisation of Kupffer cells, 2021, Gut
  • CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics, 2021, Bioengineering
  • Merit of an Ursodeoxycholic Acid Clinical Trial in COVID-19 Patients, 2020, Vaccines
  • Grant application outcomes for biomedical researchers who participated in the National Research Mentoring Network's Grant Writing Coaching Programs, 2020, PLoS ONE

Throughout their career, Clifford J. Steer has frequently collaborated with several coauthors, including:

  • Walter C. Low
  • Guisheng Song
  • Anala V. Shetty
  • Ningning Liu
  • Daniel P. Collins

Best Publications

  • A guiding map for inflammation

    Mihai G Netea;Frances Balkwill;Michel Chonchol;Fabio Cominelli

  • Molecular mechanisms of hepatocellular carcinoma.

    Rajagopal N. Aravalli;Clifford J. Steer;Erik N. K. Cressman

  • A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

    Cecilia M.P. Rodrigues;Guangsheng Fan;Xiaoming Ma;Betsy T. Kren

  • The role of p53 in apoptosis.

    Joana D Amaral;Joana M Xavier;Clifford J Steer;Cecília M Rodrigues

  • Bile acids: regulation of apoptosis by ursodeoxycholic acid

    Joana D. Amaral;Ricardo J.S. Viana;Rita M. Ramalho;Clifford J. Steer

  • Ursodeoxycholic Acid May Inhibit Deoxycholic Acid-Induced Apoptosis by Modulating Mitochondrial Transmembrane Potential and Reactive Oxygen Species Production

    Cecilia M. P. Rodrigues;Guangsheng Fan;Phillip Y. Wong;Betsy T. Kren

  • Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

    Aaron L. Sarver;Amy J. French;Pedro M. Borralho;Venugopal Thayanithy

  • In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides.

    Betsy T. Kren;Paramita Bandyopadhyay;Clifford J. Steer

  • Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease

    C. Dirk Keene;Cecilia M. P. Rodrigues;Cecilia M. P. Rodrigues;Tacjana Eich;Manik S. Chhabra

  • Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation.

    Cecilia Mp Rodrigues;Xiaoming Ma;Cheryle Linehan-Stieers;Guangsheng Fan

  • Uptake and distribution of placental glucocerebrosidase in rat hepatic cells and effects of sequential deglycosylation

    F.Scott Furbish;Clifford J. Steer;Nancy L. Krett;John A. Barranger

  • Similar Patterns of Mitochondrial Vulnerability and Rescue Induced by Genetic Modification of α-Synuclein, Parkin, and DJ-1 in Caenorhabditis elegans

    Rina Ved;Shamol Saha;Beth Westlund;Celine Perier

  • Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide.

    Betsy T. Kren;Bhupesh Parashar;Paramita Bandyopadhyay;Namita Roy Chowdhury

  • Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats.

    Cecilia M. P. Rodrigues;Susana Solá;Susana Solá;Zhenhong Nan;Rui E. Castro

  • Cellular and molecular mechanisms of hepatocellular carcinoma: an update.

    Rajagopal N. Aravalli;Erik N. K. Cressman;Clifford J. Steer

  • MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells.

    Pedro M. Borralho;Betsy T. Kren;Rui E. Castro;Isabel B. Moreira da Silva

  • MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis

    Betsy T. Kren;Phillip Y P Wong;Aaron L Sarver;Xiaoxiao Zhang

  • Image averaging of flexible fibrous macromolecules: The clathrin triskelion has an elastic proximal segment

    Eva Kocsis;Benes L. Trus;Clifford J. Steer;Margaret E. Bisher

  • The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases

    Sheila Vang;Katie Longley;Clifford J. Steer;Walter C. Low

  • miR-34a Regulates Mouse Neural Stem Cell Differentiation

    Márcia M. Aranha;Daniela M. dos Santos;Susana de Sola;Clifford J. Steer

Frequent Co-Authors

Cecília M. P. Rodrigues
Cecília M. P. Rodrigues University of Lisbon
Subbaya Subramanian
Subbaya Subramanian University of Minnesota
Gregory M. Vercellotti
Gregory M. Vercellotti University of Minnesota
David A. Largaespada
David A. Largaespada University of Minnesota
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Michael P. Murtaugh
Michael P. Murtaugh University of Minnesota
Kenneth D. R. Setchell
Kenneth D. R. Setchell Cincinnati Children's Hospital Medical Center
Ann L. Oberg
Ann L. Oberg Mayo Clinic

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