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Gregory M. Vercellotti

Gregory M. Vercellotti

D-Index & Metrics

Medicine

D-Index
88
Citations
29084
World Ranking
13140
National Ranking
6705

Overview

Gregory M. Vercellotti is affiliated with the University of Minnesota in the United States and has a research record primarily within the field of Medicine. Their work spans multiple subfields, including Genetics, Hematology, Molecular Biology, Physiology, and Immunology.

Their contributions cover a range of interconnected topics, focusing on:

  • Hemoglobinopathies and Related Disorders
  • Heme Oxygenase-1 and Carbon Monoxide
  • Erythrocyte Function and Pathophysiology
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Hematopoietic Stem Cell Transplantation
  • Iron Metabolism and Disorders
  • Bone and Joint Diseases

Vercellotti has authored multiple scientific papers across various prominent journals. Notable recent publications include:

  • "The multifaceted role of ischemia/reperfusion in sickle cell anemia," 2020, Journal of Clinical Investigation
  • "Vasculo-toxic and pro-inflammatory action of unbound haemoglobin, haem and iron in transfusion-dependent patients with haemolytic anaemias," 2021, British Journal of Haematology
  • "JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte-endothelial proadhesive interactions," 2023, Journal of Thrombosis and Haemostasis
  • "Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease," 2020, Blood
  • "Identification of a Heme Activation Site on the MD-2/TLR4 Complex," 2020, Frontiers in Immunology

Among the journals where Vercellotti frequently publishes are:

  • Blood
  • Transplantation and Cellular Therapy
  • Frontiers in Immunology
  • British Journal of Haematology
  • bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in their research include:

  • John D. Belcher
  • Julia Nguyen
  • Fuad Abdulla
  • Shernan G. Holtan
  • Brian C. Betts

Best Publications

  • Ferritin: a cytoprotective antioxidant strategem of endothelium.

    György Balla;Harry S. Jacob;József Balla;M. Rosenberg

  • C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor

    Jaroslav Cermak;Nigel S. Key;Ronald R. Bach;Jozsef Balla

  • Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat

    Karl A. Nath;Gyorgy Balla;Gregory M. Vercellotti;Jozsef Balla

  • Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

    Dominik J. Schaer;Paul W. Buehler;Abdu I. Alayash;John D. Belcher

  • Pro-oxidant and cytotoxic effects of circulating heme

    Viktória Jeney;József Balla;Akihiro Yachie;Zsuzsa Varga

  • Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

    John D. Belcher;Chunsheng Chen;Julia Nguyen;Liming Milbauer

  • Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage.

    Jozsef Balla;Harry S. Jacob;Gyorgy Balla;Karl Nath

  • Transplantation of discordant xenografts: a review of progress.

    Jeffrey L Platt;Gregory M Vercellotti;Agustin P Dalmasso;Agustin P Dalmasso;Arthur J Matas

  • Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants

    K. Sato;J. Balla;L. Otterbein;R. N. Smith

  • Hemin: a possible physiological mediator of low density lipoprotein oxidation and endothelial injury.

    G. Balla;Harry S Jacob;J. W. Eaton;John D Belcher

  • Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion

    John D. Belcher;Paul H. Marker;Jill P. Weber;Robert P. Hebbel

  • Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species.

    G Balla;G M Vercellotti;U Muller-Eberhard;J Eaton

  • Release of heparan sulfate from endothelial cells: implications for pathogenesis of hyperacute rejection

    Jeffrey L. Platt;Gregory M. Vercellotti;Bonnie J. Lindman;Theodore R. Oegema

  • Respiratory syncytial virus infection in immunocompromised adults.

    J. A. Englund;C. J. Sullivan;M. C. Jordan;L. P. Dehner

  • Mechanism of complement activation in the hyperacute rejection of porcine organs transplanted into primate recipients

    A. P. Dalmasso;G. M. Vercellotti;R. J. Fischel;R. M. Bolman

  • Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

    Barbara Wegiel;David Gallo;Eva Csizmadia;Clair Harris

  • Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice

    John D. Belcher;Hemachandra Mahaseth;Thomas E. Welch;Leo E. Otterbein

  • Inhibition of complement-mediated endothelial cell cytotoxicity by decay-accelerating factor. Potential for prevention of xenograft hyperacute rejection.

    Agustin P. Dalmasso;Gregory M. Vercellotti;Jeffrey L. Platt;Fritz H. Bach

  • Activation of plasma complement by perfluorocarbon artificial blood: probable mechanism of adverse pulmonary reactions in treated patients and rationale for corticosteroids prophylaxis

    Gregory M. Vercellotti;Dale E. Hammerschmidt;Philip R. Craddock;Harry S. Jacob

  • Reperfusion injury pathophysiology in sickle transgenic mice.

    U. Raymond Osarogiagbon;Stephana Choong;John D. Belcher;Gregory M. Vercellotti

Frequent Co-Authors

Harry S. Jacob
Harry S. Jacob University of Minnesota
Robert P. Hebbel
Robert P. Hebbel University of Minnesota
Karl A. Nath
Karl A. Nath Mayo Clinic
Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota
John W. Eaton
John W. Eaton University of Louisville
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Agustin P. Dalmasso
Agustin P. Dalmasso University of Minnesota
Clifford J. Steer
Clifford J. Steer University of Minnesota
Todd E. DeFor
Todd E. DeFor University of Minnesota
Jeffrey S. Miller
Jeffrey S. Miller University of Minnesota

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