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Medicine

D-Index
81
Citations
27420
World Ranking
16513
National Ranking
8295

Overview

Todd E. DeFor is affiliated with the University of Minnesota in the United States and conducts research primarily within the field of Medicine, with a particular focus on Hematology. Their work encompasses multiple subfields including Oncology, Immunology, Public Health, Environmental and Occupational Health, and Pediatrics, Perinatology and Child Health.

The scientist's research concentrates on several main topics, notably Hematopoietic Stem Cell Transplantation, Acute Lymphoblastic Leukemia research, and the quality of life among Childhood Cancer Survivors. Additional research interests include CAR-T cell therapy, Immune Cell Function and Interaction, Renal Transplantation Outcomes and Treatments, and Mesenchymal stem cell research.

Recent publications authored or coauthored by Todd E. DeFor cover a range of clinical and translational studies. These include:

  • "First-in-human phase 1 trial of induced regulatory T cells for graft-versus-host disease prophylaxis in HLA-matched siblings," 2021, Blood Advances
  • "Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors," 2024, Journal of Clinical Oncology
  • "Comparative analysis of antibiotic exposure association with clinical outcomes of chemotherapy versus immunotherapy across three tumour types," 2020, ESMO Open
  • "Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma," 2023, Science Translational Medicine
  • "Steroid-dependent acute GVHD after allogeneic hematopoietic cell transplantation: risk factors and clinical outcomes," 2021, Blood Advances

The frequent collaborators in their research include Daniel J. Weisdorf, Claudio G. Brunstein, Margaret L. MacMillan, Shernan G. Holtan, and Najla El Jurdi.

Todd E. DeFor publishes extensively in specialized journals related to transplantation and hematology. The most common publication venues are:

  • Transplantation and Cellular Therapy
  • Blood
  • Blood Advances
  • Biology of Blood and Marrow Transplantation
  • Journal of Clinical Oncology

Best Publications

  • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer.

    Jeffrey S. Miller;Yvette Soignier;Angela Panoskaltsis-Mortari;Sarah A. McNearney

  • Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival.

    John E. Wagner;Juliet N. Barker;Todd E. DeFor;K. Scott Baker

  • Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics.

    Claudio G. Brunstein;Jeffrey S. Miller;Qing Cao;David H. McKenna

  • Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy

    Juliet N. Barker;Daniel J. Weisdorf;Todd E. DeFor;Bruce R. Blazar

  • Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease

    Claudio G. Brunstein;Juliet N. Barker;Daniel J. Weisdorf;Todd E. DeFor

  • Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood

    Claudio G. Brunstein;Jonathan A. Gutman;Daniel J. Weisdorf;Ann E. Woolfrey

  • Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen–matched unrelated donor bone marrow: results of a matched-pair analysis

    Juliet N. Barker;Stella M. Davies;Todd DeFor;Norma K. C. Ramsay

  • Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning.

    Juliet N. Barker;Daniel J. Weisdorf;Todd E. DeFor;Bruce R. Blazar

  • Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants

    Stella M. Davies;Loredana Ruggieri;Todd DeFor;John E. Wagner

  • Clearance of Acute Myeloid Leukemia by Haploidentical Natural Killer Cells Is Improved Using IL-2 Diphtheria Toxin Fusion Protein

    Veronika Bachanova;Sarah Cooley;Todd E. Defor;Michael R. Verneris

  • Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems.

    Margaret L MacMillan;Daniel J Weisdorf;John E Wagner;Todd E DeFor

  • Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation.

    Shernan G. Holtan;Todd E. DeFor;Aleksandr Lazaryan;Nelli Bejanyan

  • Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

    Claudio G. Brunstein;Jeffrey S. Miller;David H. McKenna;Keli L. Hippen

  • First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

    Rizwan Romee;Sarah Cooley;Melissa M. Berrien-Elliott;Peter Westervelt

  • Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999.

    Charles Peters;Lawrence R. Charnas;Ye Tan;Richard S. Ziegler

  • Searching for unrelated donor hematopoietic stem cells: Availability and speed of umbilical cord blood versus bone marrow

    Juliet N Barker;Timothy P Krepski;Todd E DeFor;Stella M Davies

  • Marked increased risk of Epstein-Barr virus-related complications with the addition of antithymocyte globulin to a nonmyeloablative conditioning prior to unrelated umbilical cord blood transplantation

    Claudio G. Brunstein;Daniel J. Weisdorf;Todd DeFor;Juliet N. Barker

  • New Malignancies After Blood or Marrow Stem-Cell Transplantation in Children and Adults: Incidence and Risk Factors

    K. Scott Baker;Todd E. DeFor;Linda J. Burns;Norma K.C. Ramsay

  • Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft.

    John E Wagner;Claudio G Brunstein;Anthony E. Boitano;Todd E. DeFor

  • Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial.

    M L MacMillan;B R Blazar;T E DeFor;J E Wagner

Frequent Co-Authors

Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota
John E. Wagner
John E. Wagner University of Minnesota
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Jeffrey S. Miller
Jeffrey S. Miller University of Minnesota
Michael R. Verneris
Michael R. Verneris University of Colorado Denver
Philip B. McGlave
Philip B. McGlave University of Minnesota
Paul J. Orchard
Paul J. Orchard University of Minnesota
Angela Panoskaltsis-Mortari
Angela Panoskaltsis-Mortari University of Minnesota
Jakub Tolar
Jakub Tolar University of Minnesota
Navneet S. Majhail
Navneet S. Majhail Cleveland Clinic

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