Miguel P. Soares focuses on Heme, Heme oxygenase, Immunology, Cell biology and Pharmacology. His study in Heme is interdisciplinary in nature, drawing from both Bilirubin and Cytoprotection, Apoptosis. His Heme oxygenase study combines topics in areas such as Cancer research and p38 mitogen-activated protein kinases.
His Immunology research incorporates themes from HMOX1, Cyclosporin a and Enzyme. His study in Cell biology is interdisciplinary in nature, drawing from both Tumor necrosis factor alpha and Transactivation. His study looks at the relationship between Pharmacology and topics such as Transplantation, which overlap with Reperfusion injury.
His scientific interests lie mostly in Immunology, Heme, Heme oxygenase, Cell biology and Transplantation. His work focuses on many connections between Immunology and other disciplines, such as Plant disease resistance, that overlap with his field of interest in Host and Immunity. His Heme research is multidisciplinary, incorporating elements of Apoptosis, Hemoglobin and Pharmacology.
In general Heme oxygenase, his work in HMOX1 is often linked to Carbon monoxide-releasing molecules linking many areas of study. As a member of one scientific family, he mostly works in the field of Transplantation, focusing on Hamster and, on occasion, Andrology. His Cancer research research focuses on Tumor necrosis factor alpha and how it relates to IκBα.
His primary areas of study are Immunology, Heme, Cell biology, Immunity and Microbiology. His studies deal with areas such as Plant disease resistance, Disease and Stem cell as well as Immunology. Particularly relevant to Heme oxygenase is his body of work in Heme.
The concepts of his Heme oxygenase study are interwoven with issues in Vimentin and Cancer research. His Cell biology research is multidisciplinary, incorporating perspectives in Carbohydrate metabolism and Metabolism. In his research, Intracellular parasite, Intracellular, Biliverdin and Tumor necrosis factor alpha is intimately related to Effector, which falls under the overarching field of Immunity.
His primary scientific interests are in Immunology, Heme, Immunity, Disease and Innate immune system. His Immunology research integrates issues from Microbiome, Pathogenic organism and Risk analysis. His Heme research is under the purview of Biochemistry.
The Immunity study combines topics in areas such as Plant disease resistance, Pathogenic bacteria, Bacteria, Immunopathology and Tissue damage. His work deals with themes such as Malaria, Host, Plasmodium, HMOX1 and Acute kidney injury, which intersect with Disease. His Microbiology research incorporates elements of Biliverdin, Heme oxygenase, Intracellular, Intracellular parasite and Effector.
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Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
Leo E. Otterbein;Leo E. Otterbein;Fritz H. Bach;Jawed Alam;Miguel P. Soares.
Nature Medicine (2000)
Heme oxygenase-1: unleashing the protective properties of heme
Leo E. Otterbein;Miguel P. Soares;Kenichiro Yamashita;Fritz H. Bach.
Trends in Immunology (2003)
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis.
Sophie Brouard;Leo E. Otterbein;Josef Anrather;Edda Tobiasch.
Journal of Experimental Medicine (2000)
Disease Tolerance as a Defense Strategy
Ruslan Medzhitov;David S. Schneider;Miguel P. Soares.
Mechanisms of Cell Protection by Heme Oxygenase-1
Raffaella Gozzelino;Viktoria Jeney;Miguel P. Soares.
Annual Review of Pharmacology and Toxicology (2010)
Expression of heme oxygenase-1 can determine cardiac xenograft survival
M. P. Soares;Y. Lin;J. Anrather;E. Csizmadia.
Nature Medicine (1998)
Different faces of the heme-heme oxygenase system in inflammation
Frank A. D. T. G. Wagener;Hans-Dieter Volk;Dean Willis;Nader G. Abraham.
Pharmacological Reviews (2003)
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury
Leo E Otterbein;Brian S Zuckerbraun;Manabu Haga;Fang Liu.
Nature Medicine (2003)
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
Ana Pamplona;Ana Pamplona;Ana Ferreira;József Balla;Viktória Jeney.
Nature Medicine (2007)
Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants
K. Sato;J. Balla;L. Otterbein;R. N. Smith.
Journal of Immunology (2001)
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