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Valery N. Bochkov

Valery N. Bochkov

D-Index & Metrics

Biology and Biochemistry

D-Index
41
Citations
14496
World Ranking
19526
National Ranking
176

Overview

Valery N. Bochkov is affiliated with the University of Graz in Austria and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research output spans various subfields including molecular biology, immunology, biochemistry, oncology, and plant science.

Their recent publications cover a range of topics relevant to inflammation, oxidative stress, and lipid signaling. Notable papers include:

  • Natural products in drug discovery: advances and opportunities (2021) published in Nature Reviews Drug Discovery
  • Synergy between 15-lipoxygenase and secreted PLA 2 promotes inflammation by formation of TLR4 agonists from extracellular vesicles (2020) in Proceedings of the National Academy of Sciences
  • Oxidized phospholipids are biomarkers, drug targets, and drug leads (2022) in Frontiers in Drug Discovery
  • Characterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling (2022) in Metabolites
  • Cooperative induction of CXCL chemokines by inflammatory cytokines and oxidized phospholipids (2024) in Immunology

The scientist often collaborates with several frequent co-authors, including:

  • Bernd Gesslbauer
  • Olga Oskolkova
  • Alma Hodzic
  • Rudolf Bauer
  • Philipp Jokesch

Bochkov's work is regularly published in venues such as:

  • Free Radical Biology and Medicine
  • Journal of Lipid Research
  • Antioxidants
  • Nature Reviews Drug Discovery
  • Proceedings of the National Academy of Sciences

The main topics of Bochkov's research address a variety of biochemical and molecular processes, particularly focusing on:

  • Neutrophil, myeloperoxidase, and oxidative mechanisms
  • Antioxidant activity and oxidative stress
  • Sphingolipid metabolism and signaling
  • Atherosclerosis and cardiovascular diseases
  • Chemokine receptors and signaling
  • Metabolomics and mass spectrometry studies
  • Natural product bioactivities and synthesis

Best Publications

  • Natural products in drug discovery: advances and opportunities.

    Atanas G Atanasov;Sergey B Zotchev;Verena M Dirsch

  • Discovery and resupply of pharmacologically active plant-derived natural products: A review.

    Atanas G. Atanasov;Birgit Waltenberger;Eva-Maria Pferschy-Wenzig;Thomas Linder

  • Generation and Biological Activities of Oxidized Phospholipids

    Valery N. Bochkov;Olga V. Oskolkova;Konstantin G. Birukov;Anna-Liisa Levonen

  • Protective role of phospholipid oxidation products in endotoxin-induced tissue damage

    Valery N. Bochkov;Alexandra Kadl;Joakim Huber;Florian Gruber

  • Expression of Heme Oxygenase-1 in Human Vascular Cells Is Regulated by Peroxisome Proliferator-Activated Receptors

    Gerhard Krönke;Alexandra Kadl;Elena Ikonomu;Stefan Blüml

  • Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

    Valery N. Bochkov;Diana Mechtcheriakova;Marcus Lucerna;Joakim Huber

  • 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

    Stefan Uderhardt;Martin Herrmann;Olga V. Oskolkova;Susanne Aschermann

  • Oxidized Phospholipids Induce Expression of Human Heme Oxygenase-1 Involving Activation of cAMP-responsive Element-binding Protein

    Gerhard Krönke;Valery N. Bochkov;Joakim Huber;Florian Gruber

  • Epoxycyclopentenone-Containing Oxidized Phospholipids Restore Endothelial Barrier Function via Cdc42 and Rac

    Konstantin G. Birukov;Valery N. Bochkov;Anna A. Birukova;Kamon Kawkitinarong

  • Oxidized Phospholipids Trigger Atherogenic Inflammation in Murine Arteries

    Alexander Furnkranz;Andreas Schober;Valery N. Bochkov;Pavel Bashtrykov

  • Expression of cell adhesion molecule T-cadherin in the human vasculature

    Danila Ivanov;Maria Philippova;Julia Antropova;Farida Gubaeva

  • Oxidized Phospholipids Reduce Vascular Leak and Inflammation in Rat Model of Acute Lung Injury

    Stephanie Nonas;Ian Miller;Kamon Kawkitinarong;Santipongse Chatchavalvanich

  • Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways

    Taras Afonyushkin;Olga V. Oskolkova;Maria Philippova;Therese J. Resink

  • Nrf2 Regulates Antioxidant Gene Expression Evoked by Oxidized Phospholipids in Endothelial Cells and Murine Arteries In Vivo

    Henna-Kaisa Jyrkkänen;Emilia Kansanen;Matias Inkala;Annukka M. Kivelä

  • Identification of proteins associating with glycosylphosphatidylinositol- anchored T-cadherin on the surface of vascular endothelial cells: role for Grp78/BiP in T-cadherin-dependent cell survival.

    Maria Philippova;Danila Ivanov;Manjunath B. Joshi;Emmanouil Kyriakakis

  • Oxidized Phospholipids Negatively Regulate Dendritic Cell Maturation Induced by TLRs and CD40

    Stefan Blüml;Stefanie Kirchberger;Valery N. Bochkov;Gerhard Krönke

  • Oxidized Phospholipids Stimulate Angiogenesis Via Autocrine Mechanisms, Implicating a Novel Role for Lipid Oxidation in the Evolution of Atherosclerotic Lesions

    Valery N. Bochkov;Maria Philippova;Olga Oskolkova;Alexandra Kadl

  • Autophagy Is Induced by UVA and Promotes Removal of Oxidized Phospholipids and Protein Aggregates in Epidermal Keratinocytes

    Yi Zhao;Cheng-Feng Zhang;Heidemarie Rossiter;Leopold Eckhart

  • ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.

    Olga Oskolkova;Taras Afonyushkin;Alexander Leitner;Elena Von Schlieffen

  • Discovery and resupply of pharmacologically active plant-derived natural products: A review - Infographic

    Atanas G. Atanasov;Birgit Waltenberger;Eva-Maria Pferschy-Wenzig;Thomas Linder

Frequent Co-Authors

Bernd R. Binder
Bernd R. Binder Medical University of Vienna
Verena M. Dirsch
Verena M. Dirsch University of Vienna
Erwin Tschachler
Erwin Tschachler Medical University of Vienna
Konstantin G. Birukov
Konstantin G. Birukov University of Chicago
Atanas G. Atanasov
Atanas G. Atanasov Medical University of Vienna
Daniela Schuster
Daniela Schuster Paracelsus Medical University
Anna A. Birukova
Anna A. Birukova University of Maryland, Baltimore
Norbert Leitinger
Norbert Leitinger University of Virginia
Gerhard Krönke
Gerhard Krönke Charité - University Medicine Berlin
Hermann Stuppner
Hermann Stuppner University of Innsbruck

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