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Immunology

D-Index
58
Citations
13518
World Ranking
3502
National Ranking
241

Overview

Gerhard Krönke is affiliated with Charité - University Medicine Berlin in Germany. Their research spans medicine and immunology, with a significant focus on rheumatology, oncology, molecular biology, and infectious diseases.

Their scientific contributions extensively cover the fields of immunology and microbiology, particularly concentrating on immune mechanisms and cell therapies.

The main topics of Gerhard Krönke's work include:

  • Rheumatoid Arthritis Research and Therapies
  • CAR-T cell therapy research
  • Systemic Lupus Erythematosus Research
  • Immune cells in cancer
  • T-cell and B-cell Immunology
  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research

Key recent publications showcase their focus on CAR-T cell therapy and autoimmune diseases:

  • "Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus," 2022, published in Nature Medicine
  • "CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up," 2024, published in New England Journal of Medicine
  • "CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus," 2021, published in New England Journal of Medicine
  • "Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis," 2020, published in Nature Communications
  • "The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts," 2021, published in Immunity

Gerhard Krönke frequently collaborates with fellow researchers such as Georg Schett, Arnd Kleyer, David Simón, Koray Taşçılar, and Johannes Knitza, reflecting a broad network within rheumatology and immunology research communities.

The scientist regularly publishes in established venues, including:

  • Annals of the Rheumatic Diseases
  • Frontiers in Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Scientific Reports

Gerhard Krönke's body of work integrates clinical and translational research methods applied to autoimmune diseases and immuno-oncology, emphasizing cellular therapies and inflammatory process regulation.

Best Publications

  • Locally renewing resident synovial macrophages provide a protective barrier for the joint

    Stephan Culemann;Anika Grüneboom;José Ángel Nicolás-Ávila;Daniela Weidner

  • CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus

    Dimitrios Mougiakakos;Gerhard Krönke;Simon Völkl;Sascha Kretschmann

  • Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

    Narges Tajik;Michael Frech;Oscar Schulz;Fabian Schälter

  • TNF-induced structural joint damage is mediated by IL-1

    Jochen Zwerina;Kurt Redlich;Karin Polzer;Leo Joosten

  • Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

    Katrin Palumbo-Zerr;Pawel Zerr;Alfiya Distler;Judith Fliehr

  • Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune disease.

    René Pfeifle;Tobias Rothe;Natacha Ipseiz;Hans U Scherer

  • Autophagy regulates TNFα-mediated joint destruction in experimental arthritis

    Neng-Yu Lin;Christian Beyer;Andreas Giessl;Trayana Kireva

  • Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo.

    Roland Axmann;Christina Böhm;Gerhard Krönke;Jochen Zwerina

  • Platelet-derived serotonin links vascular disease and tissue fibrosis

    Clara Dees;Alfiya Akhmetshina;Pawel Zerr;Nicole Reich

  • Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

    Ulrike Harre;Stefanie C. Lang;René Pfeifle;Yoann Rombouts

  • A network of trans-cortical capillaries as mainstay for blood circulation in long bones

    Anika Grüneboom;Ibrahim Hawwari;Daniela Weidner;Stephan Culemann

  • Expression of Heme Oxygenase-1 in Human Vascular Cells Is Regulated by Peroxisome Proliferator-Activated Receptors

    Gerhard Krönke;Alexandra Kadl;Elena Ikonomu;Stefan Blüml

  • 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

    Stefan Uderhardt;Martin Herrmann;Olga V. Oskolkova;Susanne Aschermann

  • The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.

    Jasna Friščić;Martin Böttcher;Christiane Reinwald;Heiko Bruns

  • Periarticular bone structure in rheumatoid arthritis patients and healthy individuals assessed by high-resolution computed tomography.

    Christian M. Stach;Michael Bäuerle;Matthias Englbrecht;Gerhard Kronke

  • 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.

    Gerhard Krönke;Julia Katzenbeisser;Stefan Uderhardt;Mario M. Zaiss

  • Oxidized Phospholipids Trigger Atherogenic Inflammation in Murine Arteries

    Alexander Furnkranz;Andreas Schober;Valery N. Bochkov;Pavel Bashtrykov

  • Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche

    Yubin Luo;Guang-Liang Chen;Nicole Hannemann;Natacha Ipseiz

  • IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.

    Maria Faas;Natacha Ipseiz;Jochen Ackermann;Stephan Culemann

  • SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases.

    David Simon;Koray Tascilar;Filippo Fagni;Gerhard Krönke

  • Oxidized Phospholipids Negatively Regulate Dendritic Cell Maturation Induced by TLRs and CD40

    Stefan Blüml;Stefanie Kirchberger;Valery N. Bochkov;Gerhard Krönke

Frequent Co-Authors

Georg Schett
Georg Schett University of Erlangen-Nuremberg
Martin Herrmann
Martin Herrmann University of Erlangen-Nuremberg
Jörg H W Distler
Jörg H W Distler University of Erlangen-Nuremberg
David Simon
David Simon Beth Israel Deaconess Medical Center
Falk Nimmerjahn
Falk Nimmerjahn University of Erlangen-Nuremberg
Jochen Zwerina
Jochen Zwerina University of Erlangen-Nuremberg
Norbert Leitinger
Norbert Leitinger University of Virginia
Oliver Distler
Oliver Distler University of Zurich
Bernd R. Binder
Bernd R. Binder Medical University of Vienna
Stefan Wirtz
Stefan Wirtz University of Erlangen-Nuremberg

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