His primary areas of investigation include Immunology, Colitis, Cytokine, T cell and Pathogenesis. He has researched Immunology in several fields, including Inflammatory bowel disease and Ulcerative colitis. His work is dedicated to discovering how Colitis, Oxazolone are connected with Barrier function, Acute colitis, Acquired immune system and Immunity and other disciplines.
The Cytokine study which covers Molecular biology that intersects with Ileum, Reporter gene, Transcriptional regulation and Small intestine. His T cell study incorporates themes from Malignancy, Interleukin 23, Experimental autoimmune encephalomyelitis, Signal transduction and Knockout mouse. Stefan Wirtz usually deals with Pathogenesis and limits it to topics linked to Adoptive cell transfer and Bacterial antigen.
Stefan Wirtz mainly focuses on Immunology, Immune system, Colitis, Inflammation and Cancer research. The Immunology study combines topics in areas such as Inflammatory bowel disease and Ulcerative colitis. His Inflammatory bowel disease research integrates issues from Crohn's disease and Pathogenesis.
His study in Interleukin extends to Colitis with its themes. His study focuses on the intersection of Cancer research and fields such as Colorectal cancer with connections in the field of Pathology and In vivo. As a member of one scientific family, Stefan Wirtz mostly works in the field of Cytokine, focusing on Molecular biology and, on occasion, Lamina propria.
His primary scientific interests are in Immune system, Immunology, Innate lymphoid cell, Inflammation and Colitis. His study in Immune system is interdisciplinary in nature, drawing from both Cancer research, Homing, Cytokine, Lung and Cell type. His Immunology study combines topics in areas such as Barrier function, Experimental colitis and Intestinal epithelium.
His research investigates the connection with Innate lymphoid cell and areas like Cell biology which intersect with concerns in Adoptive cell transfer, Tissue homeostasis and In vivo. His work carried out in the field of Colitis brings together such families of science as T cell and Inflammatory bowel disease. His work in the fields of IL-2 receptor overlaps with other areas such as Tec kinase.
His primary areas of study are Inflammation, Immune system, Immunology, Arthritis and Cancer research. The study incorporates disciplines such as Secondary infection, Compartmentalization, Autoimmune disease, Inflammatory arthritis and Barrier function in addition to Inflammation. Stefan Wirtz has included themes like Molecular biology, Paneth cell, Interferon and Janus kinase in his Immune system study.
His work deals with themes such as Lung and In vivo, which intersect with Immunology. Stefan Wirtz interconnects Germinal center, BCL6, B cell, Autoantibody and Rheumatoid arthritis in the investigation of issues within Arthritis. His studies in Cancer research integrate themes in fields like Homeostasis, Colorectal cancer, Intestinal Cancer and Innate immune system.
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Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study
Daniel D. Murray;Kazuo Suzuki;Matthew Law;Jonel Trebicka.
PLOS ONE (2015)
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.
R Atreya;J Mudter;S Finotto;J Müllberg.
Nature Medicine (2000)
Chemically induced mouse models of intestinal inflammation.
Stefan Wirtz;Clemens Neufert;Benno Weigmann;Markus F Neurath.
Nature Protocols (2007)
STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
Geethanjali Pickert;Clemens Neufert;Moritz Leppkes;Yan Zheng.
Journal of Experimental Medicine (2009)
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.
Imke Tiede;Gerhard Fritz;Susanne Strand;Daniela Poppe.
Journal of Clinical Investigation (2003)
IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
Ping Shen;Toralf Roch;Vicky Lampropoulou;Richard A. O’Connor.
TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling
Christoph Becker;Massimo C. Fantini;Christoph Schramm;Hans A. Lehr.
Chemically induced mouse models of acute and chronic intestinal inflammation
Stefan Wirtz;Vanessa Popp;Markus Kindermann;Katharina Gerlach.
Nature Protocols (2017)
Mouse models of inflammatory bowel disease.
Stefan Wirtz;Markus F. Neurath.
Advanced Drug Delivery Reviews (2007)
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F
Moritz Leppkes;Christoph Becker;Ivaylo I. Ivanov;Sebastian Hirth.
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