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Immunology

D-Index
74
Citations
30739
World Ranking
2026
National Ranking
141

Overview

Stefan Wirtz is affiliated with the University of Erlangen-Nuremberg in Germany and has a research focus spanning medicine, immunology, microbiology, biochemistry, genetics, and molecular biology. Their work extensively covers immunology, with significant contributions to subfields such as molecular biology, surgery, oncology, and genetics.

Their research topics include:

  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Gut microbiota and health
  • Eosinophilic Esophagitis
  • Inflammatory Bowel Disease
  • Helicobacter pylori-related gastroenterology studies
  • Immune cells in cancer

Recent notable publications by Stefan Wirtz cover a range of immunological and gastrointestinal studies:

  • "Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis" (2020), published in Nature Communications
  • "IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation" (2021), published in Immunity
  • "Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo" (2021), published in Journal of Extracellular Vesicles
  • "Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis" (2020), published in Nature Communications
  • "Arginase impedes the resolution of colitis by altering the microbiome and metabolome" (2020), published in Journal of Clinical Investigation

Frequent collaborators in Stefan Wirtz's research include Markus F. Neurath, Raja Atreya, Christoph Becker, Claudia Günther, and Georg Schett, indicating a consistent network of scientific cooperation.

Their work is frequently published in a range of venues specializing in immunology and gastroenterology, including:

  • Frontiers in Immunology
  • Gastroenterology
  • Journal of Crohn's and Colitis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gut

Best Publications

  • Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study

    Daniel D. Murray;Kazuo Suzuki;Matthew Law;Jonel Trebicka

  • Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.

    R Atreya;J Mudter;S Finotto;J Müllberg

  • Chemically induced mouse models of intestinal inflammation.

    Stefan Wirtz;Clemens Neufert;Benno Weigmann;Markus F Neurath

  • Chemically induced mouse models of acute and chronic intestinal inflammation

    Stefan Wirtz;Vanessa Popp;Markus Kindermann;Katharina Gerlach

  • STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

    Geethanjali Pickert;Clemens Neufert;Moritz Leppkes;Yan Zheng

  • IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

    Ping Shen;Toralf Roch;Vicky Lampropoulou;Richard A. O’Connor

  • CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

    Imke Tiede;Gerhard Fritz;Susanne Strand;Daniela Poppe

  • TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

    Christoph Becker;Massimo C. Fantini;Christoph Schramm;Hans A. Lehr

  • Mouse models of inflammatory bowel disease.

    Stefan Wirtz;Markus F. Neurath

  • RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F

    Moritz Leppkes;Christoph Becker;Ivaylo I. Ivanov;Sebastian Hirth

  • Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis

    Tamar Mchedlidze;Maximilian Waldner;Steffen Zopf;Jennifer Walker

  • TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells

    Katharina Gerlach;YouYi Hwang;Alexej Nikolaev;Raja Atreya

  • Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

    Christoph H Becker;Stefan Wirtz;Manfred Blessing;Jaana Pirhonen

  • Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

    Narges Tajik;Michael Frech;Oscar Schulz;Fabian Schälter

  • IL-6 signaling promotes tumor growth in colorectal cancer.

    C Becker;M C Fantini;S Wirtz;A Nikolaev

  • Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury: A Randomized Clinical Trial

    Alexander Zarbock;Mira Küllmar;Detlef Kindgen-Milles;Carola Wempe

  • Autophagy regulates TNFα-mediated joint destruction in experimental arthritis

    Neng-Yu Lin;Christian Beyer;Andreas Giessl;Trayana Kireva

  • In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy

    C Becker;M C Fantini;S Wirtz;A Nikolaev

  • Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

    Simon Rauber;Markus Luber;Stefanie Weber;Lisa Maul

  • Cutting Edge: IL-23 Cross-Regulates IL-12 Production in T Cell-Dependent Experimental Colitis

    Christoph Becker;Heike Dornhoff;Clemens Neufert;Massimo C. Fantini

  • Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial

    Didier Keh;Evelyn Trips;Gernot Marx;Stefan P Wirtz

  • IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1.

    Clemens Neufert;Christoph Becker;Stefan Wirtz;Massimo C. Fantini

  • TGF-beta suppresses tumor progression in colon cancer by inhibition of IL–6 trans-signaling

    C Becker;MC Fantini;C Schramm;HA Lehr

Frequent Co-Authors

Markus F. Neurath
Markus F. Neurath University of Erlangen-Nuremberg
Christoph Becker
Christoph Becker University of Erlangen-Nuremberg
Peter R. Galle
Peter R. Galle Johannes Gutenberg University of Mainz
Johannes B. Ries
Johannes B. Ries University of Trier
Manuel Seeger
Manuel Seeger University of Trier
Georg Schett
Georg Schett University of Erlangen-Nuremberg
Stefan Rose-John
Stefan Rose-John Kiel University
Richard S. Blumberg
Richard S. Blumberg Brigham and Women's Hospital
Massimo Fantini
Massimo Fantini Precision Biologics
Dennis Strand
Dennis Strand Johannes Gutenberg University of Mainz

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