D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 60 Citations 13,102 305 World Ranking 2054 National Ranking 144

Overview

What is she best known for?

The fields of study she is best known for:

  • Internal medicine
  • Gene
  • Cancer

Her main research concerns Immunology, Colitis, Inflammation, Proinflammatory cytokine and Inflammatory bowel disease. Her Immunology research is multidisciplinary, relying on both Epithelium, Cancer research and Ileitis. Her Colitis study is concerned with Internal medicine in general.

Her Inflammation research is multidisciplinary, incorporating perspectives in Intestinal mucosa, Cytokine, Immunity, Innate immune system and Macrophage. Her studies in Proinflammatory cytokine integrate themes in fields like Tumor necrosis factor alpha, Endocrinology, Interleukin and In vivo. Her work in Inflammatory bowel disease addresses issues such as Vorinostat, which are connected to fields such as Histone deacetylase inhibitor.

Her most cited work include:

  • The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines (424 citations)
  • Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure (385 citations)
  • IL-1β-converting enzyme (caspase-1) in intestinal inflammation (348 citations)

What are the main themes of her work throughout her whole career to date?

Internal medicine, Immunology, Inflammatory bowel disease, Crohn's disease and Ulcerative colitis are her primary areas of study. Britta Siegmund has included themes like Gastroenterology and Endocrinology in her Internal medicine study. Her work in Immunology addresses subjects such as Adipose tissue, which are connected to disciplines such as Adipokine.

Her studies deal with areas such as Colitis and Pathogenesis as well as Inflammatory bowel disease. Her research in Colitis intersects with topics in Pharmacology and In vivo. As a part of the same scientific family, Britta Siegmund mostly works in the field of Inflammation, focusing on Cancer research and, on occasion, Histone deacetylase.

She most often published in these fields:

  • Internal medicine (34.11%)
  • Immunology (31.20%)
  • Inflammatory bowel disease (27.99%)

What were the highlights of her more recent work (between 2018-2021)?

  • Internal medicine (34.11%)
  • Inflammatory bowel disease (27.99%)
  • Ulcerative colitis (16.91%)

In recent papers she was focusing on the following fields of study:

Britta Siegmund focuses on Internal medicine, Inflammatory bowel disease, Ulcerative colitis, Crohn's disease and Immunology. Her study focuses on the intersection of Internal medicine and fields such as Gastroenterology with connections in the field of Suppository and Randomized controlled trial. Her Inflammatory bowel disease research incorporates elements of Disease remission, Colitis and Intensive care medicine.

Her Colitis research includes themes of Interleukin 17 and Pharmacology. Her Immunology study frequently involves adjacent topics like Adipose tissue. Her Inflammation study combines topics from a wide range of disciplines, such as Cancer research, Cytokine, Gene knockdown, Homeostasis and Pathology.

Between 2018 and 2021, her most popular works were:

  • Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans. (119 citations)
  • Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. (97 citations)
  • Management of Patients With Crohn's Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting. (94 citations)

In her most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Cancer

Her primary areas of investigation include Inflammation, Internal medicine, Inflammatory bowel disease, Immunology and Immune system. Her biological study spans a wide range of topics, including Tumor necrosis factor alpha, Cancer research, Oncogene and Histone deacetylase, Vorinostat. The Ulcerative colitis, Randomized controlled trial and Alpha 1-antitrypsin deficiency research she does as part of her general Internal medicine study is frequently linked to other disciplines of science, such as Triglyceride, therefore creating a link between diverse domains of science.

The Inflammatory bowel disease study which covers Outbreak that intersects with Risk factor and Global health. Britta Siegmund combines subjects such as Adipose tissue and Leptin Deficiency with her study of Immunology. Her Immune system research incorporates themes from Multiple sclerosis, Lymphocyte, Leptin and Cytometry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

Flavio Leoni;Andrea Zaliani;Giorgio Bertolini;Giulia Porro.
Proceedings of the National Academy of Sciences of the United States of America (2002)

578 Citations

Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure

Vyacheslav Y. Melnikov;Tevfik Ecder;Giamila Fantuzzi;Britta Siegmund.
Journal of Clinical Investigation (2001)

576 Citations

IL-1β-converting enzyme (caspase-1) in intestinal inflammation

Britta Siegmund;Hans Anton Lehr;Giamila Fantuzzi;Charles A. Dinarello.
Proceedings of the National Academy of Sciences of the United States of America (2001)

483 Citations

Neutrophil-independent mechanisms of caspase-1– and IL-18–mediated ischemic acute tubular necrosis in mice

Vyacheslav Y. Melnikov;Sarah Faubel;Britta Siegmund;M. Scott Lucia.
Journal of Clinical Investigation (2002)

447 Citations

A guide to histomorphological evaluation of intestinal inflammation in mouse models

Ulrike Erben;Christoph Loddenkemper;Katja Doerfel;Simone Spieckermann.
International Journal of Clinical and Experimental Pathology (2014)

434 Citations

A guiding map for inflammation

Mihai G Netea;Frances Balkwill;Michel Chonchol;Fabio Cominelli.
Nature Immunology (2017)

398 Citations

The Histone Deacetylase Inhibitor ITF2357 Reduces Production of Pro-Inflammatory Cytokines In Vitro and Systemic Inflammation In Vivo

Flavio Leoni;Gianluca Fossati;Eli C Lewis;Jae-Kwon Lee.
Molecular Medicine (2005)

392 Citations

Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production

Britta Siegmund;Giamila Fantuzzi;Florian Rieder;Fabia Gamboni-Robertson.
American Journal of Physiology-regulatory Integrative and Comparative Physiology (2001)

380 Citations

Histone Hyperacetylation Is Associated with Amelioration of Experimental Colitis in Mice

Rainer Glauben;Arvind Batra;Inka Fedke;Martin Zeitz.
Journal of Immunology (2006)

370 Citations

Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease

Eva Martini;Susanne M. Krug;Britta Siegmund;Markus F. Neurath.
Cellular and molecular gastroenterology and hepatology (2017)

368 Citations

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