World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
75
Citations
20579
World Ranking
1496
National Ranking
108

Medicine

D-Index
78
Citations
23967
World Ranking
17988
National Ranking
945

Overview

Britta Siegmund is affiliated with Humboldt-Universität zu Berlin in Germany. Their research spans several fields primarily within medicine and biochemistry, genetics, and molecular biology.

Their extensive publication record includes work in prominent journals such as:

  • Journal of Crohn's and Colitis
  • Zeitschrift für Gastroenterologie
  • Gastroenterology
  • The American Journal of Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)

Siegmund's research focuses on key topics including:

  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Eosinophilic Esophagitis
  • Helicobacter pylori-related gastroenterology studies
  • Autoimmune and Inflammatory Disorders
  • Immunodeficiency and Autoimmune Disorders
  • Celiac Disease Research and Management

Within the broader medical sciences, their subfields of study include:

  • Genetics
  • Epidemiology
  • Immunology
  • Surgery
  • Gastroenterology

Among recent published papers featuring significant citation counts are:

  • "Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19," 2020, Nature Neuroscience
  • "Ulcerative colitis," 2020, Nature Reviews Disease Primers
  • "Management of Patients With Crohn's Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting," 2020, Gastroenterology
  • "Location is important: differentiation between ileal and colonic Crohn's disease," 2021, Nature Reviews Gastroenterology & Hepatology
  • "Personalizing Treatment in IBD: Hype or Reality in 2020? Can We Predict Response to Anti-TNF?," 2020, Frontiers in Medicine

Frequent collaborators include:

  • Silvio Danese
  • Laurent Peyrin-Biroulet
  • Raja Atreya
  • Carl Weidinger
  • Anja A. Kühl

In terms of academic contributions beyond articles, Britta Siegmund has published books with the Centre National de la Recherche Scientifique, including:

  • Methodological Handbook in Food Sustainability through Service-learning (2024)
  • Manuel méthodologique sur la durabilité alimentaire par le biais de l'apprentissage par le service (2024)

Best Publications

  • Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.

    Jenny Meinhardt;Josefine Radke;Carsten Dittmayer;Jonas Franz;Jonas Franz

  • A guiding map for inflammation

    Mihai G Netea;Frances Balkwill;Michel Chonchol;Fabio Cominelli

  • Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease

    Eva Martini;Susanne M. Krug;Britta Siegmund;Markus F. Neurath

  • A guide to histomorphological evaluation of intestinal inflammation in mouse models

    Ulrike Erben;Christoph Loddenkemper;Katja Doerfel;Simone Spieckermann

  • The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

    Flavio Leoni;Andrea Zaliani;Giorgio Bertolini;Giulia Porro

  • Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure

    Vyacheslav Y. Melnikov;Tevfik Ecder;Giamila Fantuzzi;Britta Siegmund

  • IL-1β-converting enzyme (caspase-1) in intestinal inflammation

    Britta Siegmund;Hans Anton Lehr;Giamila Fantuzzi;Charles A. Dinarello

  • Neutrophil-independent mechanisms of caspase-1– and IL-18–mediated ischemic acute tubular necrosis in mice

    Vyacheslav Y. Melnikov;Sarah Faubel;Britta Siegmund;M. Scott Lucia

  • Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans.

    Petra Bacher;Thordis Hohnstein;Eva Beerbaum;Marie Röcker

  • Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry.

    Chotima Böttcher;Stephan Schlickeiser;Marjolein A. M. Sneeboer;Desiree Kunkel

  • Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD

    Donata Lissner;Michael Schumann;Arvind Batra;Lea-Isabel Kredel

  • The Histone Deacetylase Inhibitor ITF2357 Reduces Production of Pro-Inflammatory Cytokines In Vitro and Systemic Inflammation In Vivo

    Flavio Leoni;Gianluca Fossati;Eli C Lewis;Jae-Kwon Lee

  • Histone Hyperacetylation Is Associated with Amelioration of Experimental Colitis in Mice

    Rainer Glauben;Arvind Batra;Inka Fedke;Martin Zeitz

  • Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production

    Britta Siegmund;Giamila Fantuzzi;Florian Rieder;Fabia Gamboni-Robertson

  • Leptin: A pivotal mediator of intestinal inflammation in mice ☆ ☆☆

    Britta Siegmund;Hans Anton Lehr;Giamila Fantuzzi

  • Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages.

    Hao Wu;Hao Wu;Hao Wu;Yijie Han;Yasmina Rodriguez Sillke;Yasmina Rodriguez Sillke;Hongzhang Deng

  • Extracellular ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells.

    Max Schnurr;Florian Then;Peter Galambos;Christoph Scholz

  • Anti-inflammatory activities of cAMP-elevating agents: enhancement of IL-10 synthesis and concurrent suppression of TNF production.

    Andreas Eigler;Britta Siegmund;Uta Emmerich;Klaus H. Baumann

  • Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4.

    Markus M. Heimesaat;André Fischer;Britta Siegmund;Andreas Kupz

  • Specific Type IV Phosphodiesterase Inhibitor Rolipram Mitigates Experimental Colitis in Mice

    Gunther Hartmann;Christoph Bidlingmaier;Britta Siegmund;Stefan Albrich

  • Management of Patients With Crohn's Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting.

    David T. Rubin;Maria T. Abreu;Victoria Rai;Corey A. Siegel

Frequent Co-Authors

Martin Zeitz
Martin Zeitz Charité - University Medicine Berlin
Anja A. Kühl
Anja A. Kühl Humboldt-Universität zu Berlin
Giamila Fantuzzi
Giamila Fantuzzi University of Illinois at Chicago
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Christoph Loddenkemper
Christoph Loddenkemper Charité - University Medicine Berlin
Stefan Schreiber
Stefan Schreiber Kiel University
Gerhard Rogler
Gerhard Rogler University of Zurich
Michael Hummel
Michael Hummel Charité - University Medicine Berlin
Markus M. Heimesaat
Markus M. Heimesaat Charité - University Medicine Berlin
Markus F. Neurath
Markus F. Neurath University of Erlangen-Nuremberg

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