Her main research concerns Immunology, Colitis, Inflammation, Proinflammatory cytokine and Inflammatory bowel disease. Her Immunology research is multidisciplinary, relying on both Epithelium, Cancer research and Ileitis. Her Colitis study is concerned with Internal medicine in general.
Her Inflammation research is multidisciplinary, incorporating perspectives in Intestinal mucosa, Cytokine, Immunity, Innate immune system and Macrophage. Her studies in Proinflammatory cytokine integrate themes in fields like Tumor necrosis factor alpha, Endocrinology, Interleukin and In vivo. Her work in Inflammatory bowel disease addresses issues such as Vorinostat, which are connected to fields such as Histone deacetylase inhibitor.
Internal medicine, Immunology, Inflammatory bowel disease, Crohn's disease and Ulcerative colitis are her primary areas of study. Britta Siegmund has included themes like Gastroenterology and Endocrinology in her Internal medicine study. Her work in Immunology addresses subjects such as Adipose tissue, which are connected to disciplines such as Adipokine.
Her studies deal with areas such as Colitis and Pathogenesis as well as Inflammatory bowel disease. Her research in Colitis intersects with topics in Pharmacology and In vivo. As a part of the same scientific family, Britta Siegmund mostly works in the field of Inflammation, focusing on Cancer research and, on occasion, Histone deacetylase.
Britta Siegmund focuses on Internal medicine, Inflammatory bowel disease, Ulcerative colitis, Crohn's disease and Immunology. Her study focuses on the intersection of Internal medicine and fields such as Gastroenterology with connections in the field of Suppository and Randomized controlled trial. Her Inflammatory bowel disease research incorporates elements of Disease remission, Colitis and Intensive care medicine.
Her Colitis research includes themes of Interleukin 17 and Pharmacology. Her Immunology study frequently involves adjacent topics like Adipose tissue. Her Inflammation study combines topics from a wide range of disciplines, such as Cancer research, Cytokine, Gene knockdown, Homeostasis and Pathology.
Her primary areas of investigation include Inflammation, Internal medicine, Inflammatory bowel disease, Immunology and Immune system. Her biological study spans a wide range of topics, including Tumor necrosis factor alpha, Cancer research, Oncogene and Histone deacetylase, Vorinostat. The Ulcerative colitis, Randomized controlled trial and Alpha 1-antitrypsin deficiency research she does as part of her general Internal medicine study is frequently linked to other disciplines of science, such as Triglyceride, therefore creating a link between diverse domains of science.
The Inflammatory bowel disease study which covers Outbreak that intersects with Risk factor and Global health. Britta Siegmund combines subjects such as Adipose tissue and Leptin Deficiency with her study of Immunology. Her Immune system research incorporates themes from Multiple sclerosis, Lymphocyte, Leptin and Cytometry.
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The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines
Flavio Leoni;Andrea Zaliani;Giorgio Bertolini;Giulia Porro.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure
Vyacheslav Y. Melnikov;Tevfik Ecder;Giamila Fantuzzi;Britta Siegmund.
Journal of Clinical Investigation (2001)
IL-1β-converting enzyme (caspase-1) in intestinal inflammation
Britta Siegmund;Hans Anton Lehr;Giamila Fantuzzi;Charles A. Dinarello.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Neutrophil-independent mechanisms of caspase-1– and IL-18–mediated ischemic acute tubular necrosis in mice
Vyacheslav Y. Melnikov;Sarah Faubel;Britta Siegmund;M. Scott Lucia.
Journal of Clinical Investigation (2002)
A guide to histomorphological evaluation of intestinal inflammation in mouse models
Ulrike Erben;Christoph Loddenkemper;Katja Doerfel;Simone Spieckermann.
International Journal of Clinical and Experimental Pathology (2014)
A guiding map for inflammation
Mihai G Netea;Frances Balkwill;Michel Chonchol;Fabio Cominelli.
Nature Immunology (2017)
The Histone Deacetylase Inhibitor ITF2357 Reduces Production of Pro-Inflammatory Cytokines In Vitro and Systemic Inflammation In Vivo
Flavio Leoni;Gianluca Fossati;Eli C Lewis;Jae-Kwon Lee.
Molecular Medicine (2005)
Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production
Britta Siegmund;Giamila Fantuzzi;Florian Rieder;Fabia Gamboni-Robertson.
American Journal of Physiology-regulatory Integrative and Comparative Physiology (2001)
Histone Hyperacetylation Is Associated with Amelioration of Experimental Colitis in Mice
Rainer Glauben;Arvind Batra;Inka Fedke;Martin Zeitz.
Journal of Immunology (2006)
Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease
Eva Martini;Susanne M. Krug;Britta Siegmund;Markus F. Neurath.
Cellular and molecular gastroenterology and hepatology (2017)
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