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Immunology

D-Index
83
Citations
43485
World Ranking
1412
National Ranking
94

Overview

Christoph Becker is affiliated with the University of Erlangen-Nuremberg in Germany and has contributed extensively to the fields of medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their research addresses a range of subfields including immunology, molecular biology, oncology, genetics, and surgery.

Their scholarly work focuses on several main topics, encompassing:

  • Immune cells in cancer
  • Inflammatory Bowel Disease
  • IL-33, ST2, and ILC pathways
  • Gut microbiota and health
  • Cell death mechanisms and regulation
  • Helicobacter pylori-related gastroenterology studies
  • Immune cell function and interaction

Christoph Becker has published frequently in several scientific venues. The most common publication outlets include:

  • Gut
  • Journal of Crohn's and Colitis
  • Gastroenterology
  • Cells
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers address various aspects of inflammation, cell death, and immune regulation within gastrointestinal contexts. Notable recent publications include:

  • "Cell death in the gut epithelium and implications for chronic inflammation", 2020, Nature Reviews Gastroenterology & Hepatology
  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023", 2023, Cell Death and Differentiation
  • "Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease", 2020, Nature Communications
  • "Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GeparNuevo", 2020, Annals of Oncology
  • "Cytokine-Mediated Crosstalk between Immune Cells and Epithelial Cells in the Gut", 2021, Cells

Christoph Becker has collaborated frequently with several researchers, including:

  • Markus F. Neurath
  • Raja Atreya
  • Jay V. Patankar
  • Anja A. Kühl
  • Britta Siegmund

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

    Gabriela Bindea;Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Marie Tosolini;Marie Tosolini;Marie Tosolini;Amos Kirilovsky;Amos Kirilovsky;Amos Kirilovsky

  • Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.

    R Atreya;J Mudter;S Finotto;J Müllberg

  • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7.

    Massimo C. Fantini;Christoph Becker;Giovanni Monteleone;Francesco Pallone

  • Epithelial NEMO links innate immunity to chronic intestinal inflammation

    Arianna Nenci;Christoph Becker;Andy Wullaert;Ralph Gareus

  • STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

    Geethanjali Pickert;Clemens Neufert;Moritz Leppkes;Yan Zheng

  • CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

    Imke Tiede;Gerhard Fritz;Susanne Strand;Daniela Poppe

  • Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

    Claudia Günther;Eva Martini;Nadine Wittkopf;Kerstin Amann

  • TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

    Christoph Becker;Massimo C. Fantini;Christoph Schramm;Hans A. Lehr

  • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression

    Clemens Neufert;Christoph Becker;Markus F Neurath

  • Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease

    Eva Martini;Susanne M. Krug;Britta Siegmund;Markus F. Neurath

  • RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F

    Moritz Leppkes;Christoph Becker;Ivaylo I. Ivanov;Sebastian Hirth

  • Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium

    Claudia Günther;Helmut Neumann;Markus F Neurath;Christoph Becker

  • Cutting Edge: TGF-β Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells

    Samuel Huber;Christoph Schramm;Hans A. Lehr;Amrit Mann

  • Isolation and subsequent analysis of murine lamina propria mononuclear cells from colonic tissue

    Benno Weigmann;Ingrid Tubbe;Daniel Seidel;Alex Nicolaev

  • Role of NF-kappaB in immune and inflammatory responses in the gut.

    M F Neurath;C Becker;K Barbulescu

  • IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes

    K Barbulescu;C Becker;J F Schlaak;E Schmitt

  • Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis

    Michael Lehrke;Alexander Becker;Martin Greif;Renee Stark

  • Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

    Christoph H Becker;Stefan Wirtz;Manfred Blessing;Jaana Pirhonen

  • Both IL‐12p70 and IL‐23 are synthesized during active Crohn's disease and are down‐regulated by treatment with anti‐IL‐12 p40 monoclonal antibody

    Ivan J Fuss;Christoph Becker;Zhiqiong Yang;Catherine Groden

Frequent Co-Authors

Markus F. Neurath
Markus F. Neurath University of Erlangen-Nuremberg
Stefan Wirtz
Stefan Wirtz University of Erlangen-Nuremberg
Massimo Fantini
Massimo Fantini Precision Biologics
Peter R. Galle
Peter R. Galle Johannes Gutenberg University of Mainz
Maximilian F. Reiser
Maximilian F. Reiser Ludwig-Maximilians-Universität München
Stefan Rose-John
Stefan Rose-John Kiel University
Francesco Pallone
Francesco Pallone University of Rome Tor Vergata
Michael Stürzl
Michael Stürzl University of Erlangen-Nuremberg
Michael Vieth
Michael Vieth University of Erlangen-Nuremberg
Dennis Strand
Dennis Strand Johannes Gutenberg University of Mainz

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