World's Best Scientists 2026 revealed!
Lieven Lagae

Lieven Lagae

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Neuroscience
Belgium
2026

D-Index & Metrics

Neuroscience

D-Index
89
Citations
31103
World Ranking
1142
National Ranking
8

Medicine

D-Index
89
Citations
31154
World Ranking
12633
National Ranking
147

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Belgium Leader Award
  • 2025 - Research.com Neuroscience in Belgium Leader Award

Overview

Lieven Lagae is affiliated with KU Leuven in Belgium and has concentrated their research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work covers significant subfields including Psychiatry and Mental Health, Pediatrics, Perinatology and Child Health, Physiology, Genetics, and Molecular Biology.

Their research topics prominently involve epilepsy research and treatment, pharmacological effects and toxicity studies, and tuberous sclerosis complex research. Additional areas of focus include neuroscience and neuropharmacology research, metabolism and genetic disorders, EEG and brain-computer interfaces, as well as neonatal and fetal brain pathology.

Among their recent published papers are:

  • Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial, 2020, Annals of Neurology
  • Current role of carbamazepine and oxcarbazepine in the management of epilepsy, 2020, Seizure
  • Epilepsy and cannabidiol: a guide to treatment, 2020, PubMed
  • Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome, 2022, JAMA Neurology
  • Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy, 2025, Epilepsia

Lagae has collaborated frequently with several coauthors, including Rima Nabbout, Floor E. Jansen, Anna Jansen, Sergiusz Jóźwiak, and J. Helen Cross. These collaborative efforts reflect consistent partnerships in their research publications.

They have contributed to multiple publication venues, most notably:

  • Epilepsia
  • European Journal of Paediatric Neurology
  • Neurology
  • Epilepsia Open
  • Epileptic Disorders

Best Publications

  • Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for Classification and Terminology

    Robert S. Fisher;J. Helen Cross;Jacqueline A. French;Norimichi Higurashi

  • De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancy.

    Lieve Claes;Jurgen Del-Favero;Berten Ceulemans;Lieven Lagae

  • Instruction manual for the ILAE 2017 operational classification of seizure types

    Robert S. Fisher;J. Helen Cross;Carol D'Souza;Jacqueline A. French

  • Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.

    Gillian I Rice;Jacquelyn Bond;Aruna Asipu;Rebecca L Brunette

  • Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.

    Yanick J. Crow;Diana S. Chase;Johanna Lowenstein Schmidt;Marcin Szynkiewicz

  • Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

    Gillian I Rice;Yoandris del Toro Duany;Yoandris del Toro Duany;Emma M Jenkinson;Gabriella M A Forte

  • Antenatal Maternal Anxiety is Related to HPA-Axis Dysregulation and Self-Reported Depressive Symptoms in Adolescence: A Prospective Study on the Fetal Origins of Depressed Mood

    Bea R H Van den Bergh;Ben Van Calster;Tim Smits;Sabine Van Huffel

  • KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy.

    Sarah Weckhuysen;Simone Mandelstam;Arvid Suls;Dominique Audenaert;Dominique Audenaert

  • Genetic and phenotypic heterogeneity suggest therapeutic implications in SCN2A-related disorders.

    Markus Wolff;Katrine M Johannesen;Ulrike B S Hedrich;Silvia Masnada

  • Clinical and Molecular Phenotype of Aicardi-Goutières Syndrome

    Gillian Rice;Teresa Patrick;Rekha Parmar;Claire F Taylor

  • Proposed consensus definitions for new-onset refractory status epilepticus (NORSE), febrile infection-related epilepsy syndrome (FIRES), and related conditions.

    Lawrence J. Hirsch;Nicolas Gaspard;Andreas van Baalen;Rima Nabbout

  • Pediatric Outcome After Maternal Cancer Diagnosed During Pregnancy

    Frederic Amant;Tineke Vandenbroucke;Magali Verheecke;Monica Fumagalli

  • Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial

    L Lagae;J Sullivan;K Knupp;L Laux

  • Breast cancer in pregnancy: Recommendations of an international consensus meeting

    Frédéric Amant;Sarah Deckers;Kristel Van Calsteren;Sibylle Loibl

  • Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study

    Frédéric Amant;Kristel Van Calsteren;Michael J Halaska;Mina Mhallem Gziri

  • Responses of macaque STS neurons to optic flow components: a comparison of areas MT and MST

    Lieven Lagae;Hugo Maes;Steven Raiguel;D K Xiao

  • High antenatal maternal anxiety is related to impulsivity during performance on cognitive tasks in 14- and 15-year-olds.

    Bea R.H. Van den Bergh;Maarten Mennes;Jaap Oosterlaan;Veerle Stevens

  • Gynecologic Cancers in Pregnancy: Guidelines of a Second International Consensus Meeting

    Frédéric Amant;Kristel Van Calsteren;Michael J. Halaska;Jos Beijnen

  • First-order analysis of optical flow in monkey brain

    G A Orban;L Lagae;A Verri;S Raiguel

  • Vagus nerve stimulation for drug‐resistant epilepsy: A European long‐term study up to 24 months in 347 children

    Iren Orosz;David McCormick;Nelia Zamponi;Sophia Varadkar

  • Neuroimaging of autism

    Judith S. Verhoeven;Paul De Cock;Lieven Lagae;Stefan Sunaert

Frequent Co-Authors

Berten Ceulemans
Berten Ceulemans University of Antwerp
Maarten Mennes
Maarten Mennes Radboud University
Floor E. Jansen
Floor E. Jansen Utrecht University
Paul Casaer
Paul Casaer KU Leuven
J. Helen Cross
J. Helen Cross Great Ormond Street Hospital

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