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Pedro M. Alzari

Pedro M. Alzari

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Biology and Biochemistry
France
2023

D-Index & Metrics

Chemistry

D-Index
76
Citations
16819
World Ranking
4340
National Ranking
132

Biology and Biochemistry

D-Index
79
Citations
18353
World Ranking
4400
National Ranking
112

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Pedro M. Alzari is affiliated with the Institut Pasteur in France and has a research focus primarily within Biochemistry, Genetics and Molecular Biology. Their work covers a range of subfields including Molecular Biology, Materials Chemistry, Genetics, Plant Science, and Infectious Diseases.

The scientist's research spans various main topics, notably Enzyme Structure and Function, Bacterial Genetics and Biotechnology, Genomics and Phylogenetic Studies, Bacteriophages and microbial interactions, Biochemical and Molecular Research, Tuberculosis Research and Epidemiology, and Microbial Metabolic Engineering and Bioproduction.

Their recent published papers include:

  • "SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system" (2021, Nature Communications)
  • "Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum" (2020, Nature Communications)
  • "The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB" (2022, mBio)
  • "Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex" (2021, Proceedings of the National Academy of Sciences)
  • "Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation" (2023, Nature Microbiology)

Frequent co-authors in their publications include Mariano Martínez, Anne Marie Wehenkel, Mathilde Ben Assaya, Daniela Megrian, and Ahmed Haouz.

The scientist's work has appeared in several publication venues, with multiple contributions to bioRxiv (Cold Spring Harbor Laboratory), Microbiology Resource Announcements, mBio, Nature Communications, and Proceedings of the National Academy of Sciences.

Best Publications

  • Conformations of immunoglobulin hypervariable regions.

    Cyrus Chothia;Cyrus Chothia;Arthur M. Lesk;Anna Tramontano;Michael Levitt;Michael Levitt

  • Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • Missense mutations in the catalase‐peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis

    Beate Heym;Pedro M. Alzari;Nadine Honore;Stewart T. Cole

  • Three-dimensional structure of antibodies.

    P M Alzari;M B Lascombe;R J Poljak

  • Interleukin 2 and its receptors: recent advances and new immunological functions

    Jacques Thèze;Pedro M. Alzari;Jacques Bertoglio

  • The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis

    Alejandro Buschiazzo;Marı́a F. Amaya;Marı́a L. Cremona;Alberto C. Frasch

  • Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile

    Andrew G. Watts;Iben Damager;Maria L. Amaya;Alejandro Buschiazzo

  • Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.

    M.F Amaya;A.G Watts;I Damager;A Wehenkel

  • Three-dimensional structure of a thermostable bacterial cellulase

    Michel Juy;Adolfo G. Amrt;Pedro M. Alzari;Roberta J. Poljak

  • The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU.

    S Spinelli;Q Z Liu;P M Alzari;P H Hirel

  • The Crystal Structure of the Mouse Apoptosis-Inducing Factor Aif

    María J. Maté;Miguel Ortiz-Lombardía;Brigitte Boitel;Ahmed Haouz

  • The Ser/Thr Protein Kinase PknB Is Essential for Sustaining Mycobacterial Growth

    Pablo Fernandez;Brigitte Saint-Joanis;Nathalie Barilone;Mary Jackson

  • Structural plasticity and catalysis regulation of a thermosensor histidine kinase

    Daniela Albanesi;Mariana Martín;Felipe Trajtenberg;María C. Mansilla

  • The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum.

    Pedro M Alzari;Hélè ne Souchon;Roberto Dominguez

  • A common protein fold and similar active site in two distinct families of beta-glycanases.

    Roberto Dominguez;Hélène Souchon;Silvia Spinelli;Zbigniew Dauter

  • Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential

    Annemarie Wehenkel;Marco Bellinzoni;Martin Graña;Rosario Duran

  • PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis.

    Brigitte Boitel;Miguel Ortiz-Lombardía;Rosario Durán;Fréderique Pompeo

  • The protein encoded by a murine male germ cell-specific transcript is a putative ATP-dependent RNA helicase

    P. Leroy;P. Alzari;D. Sassoon;D. Wolgemuth

  • Crystal structure of the catalytic domain of the PknB serine/threonine kinase from Mycobacterium tuberculosis.

    Miguel Ortiz-Lombardı́a;Frédérique Pompeo;Brigitte Boitel;Pedro M. Alzari

  • Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation

    Alejandro Buschiazzo;Juan E Ugalde;Marcelo E Guerin;William Shepard

  • Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

    A Villarino;R. Duran;A. Wehenkel;P. Fernandez

Frequent Co-Authors

Stewart T. Cole
Stewart T. Cole Institut Pasteur
Jacques Thèze
Jacques Thèze Institut Pasteur
Pierre Béguin
Pierre Béguin Institut Pasteur
Roberto J. Poljak
Roberto J. Poljak University of Maryland, College Park
Mary Jackson
Mary Jackson Colorado State University
Michel E. Goldberg
Michel E. Goldberg Université Paris Cité
Silvia Spinelli
Silvia Spinelli Centre national de la recherche scientifique, CNRS
Patrick England
Patrick England Institut Pasteur
Diego de Mendoza
Diego de Mendoza National University of Rosario
Alberto C.C. Frasch
Alberto C.C. Frasch National University of General San Martín

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