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Jacques Thèze

Jacques Thèze

D-Index & Metrics

Immunology

D-Index
46
Citations
6301
World Ranking
4651
National Ranking
221

Overview

Jacques Thèze is affiliated with the Institut Pasteur in France and has contributed to research primarily within the fields of immunology, microbiology, and medicine. Their work spans several subfields, notably virology, immunology, and epidemiology, focusing on mechanisms of immune response and infectious diseases.

The scientist's research predominantly addresses topics related to HIV research and treatment, cytomegalovirus and herpesvirus research, immune cell function and interaction, and immune response and inflammation.

Recent publications by Jacques Thèze include:

  • PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients, 2020, Journal of Clinical Investigation
  • Microbial Protein Binding to gC1qR Drives PLA2G1B-Induced CD4 T-Cell Anergy, 2022, Frontiers in Immunology

Their frequent co-authors include:

  • Julien Pothlichet
  • Florence Bugault
  • Louise Jeammet
  • Annalisa Meola
  • Thierry Rose

Jacques Thèze has published in well-regarded scientific venues such as the Journal of Clinical Investigation and Frontiers in Immunology, contributing to the collective understanding of immune dysfunction in viral infections.

Best Publications

  • Interleukin 2 and its receptors: recent advances and new immunological functions

    Jacques Thèze;Pedro M. Alzari;Jacques Bertoglio

  • IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells.

    O Abehsira-Amar;M Gibert;M Joliy;J Thèze

  • Preserved Central Memory and Activated Effector Memory CD4+ T-Cell Subsets in Human Immunodeficiency Virus Controllers: an ANRS EP36 Study

    Simon J Potter;Christine Lacabaratz;Olivier Lambotte;Santiago Perez-Patrigeon

  • Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.

    Jacques Theze;Judith A. Kapp;Baruj Benacerraf

  • Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin 2 receptor: relationship to the interleukin 2-binding site.

    Jean‐Louis ‐L Moreau;Markus Nabholz;Tibor Diamantstein;Thomas Malek

  • CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients--reversal by highly active anti-retroviral therapy (HAART).

    J.‐H. Colle;J.‐L. Moreau;A. Fontanet;O. Lambotte

  • Regulatory dysfunction of the interleukin-7 receptor in CD4 and CD8 lymphocytes from HIV-infected patients--effects of antiretroviral therapy.

    Jean-Hervé Colle;Jean-Louis Moreau;Arnaud Fontanet;Olivier Lambotte

  • Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells.

    Carl Waltenbaugh;Jacques Théze;Jacques Théze;Judith A. Kapp;Judith A. Kapp;Baruj Benacerraf

  • Immunosuppressive factor(s) specific for L-glutamic acid(50)-L- tyrosine(50) (GT). II. Presence of I-J determinants on the GT-suppressive factor

    Jacques Théze;Carl Waltenbaugh;Martin E. Dorf;Baruj Benacerraf

  • A programmed switch from IL-15- to IL-2-dependent activation in human NK cells.

    Anne-Hélène Pillet;Florence Bugault;Jacques Thèze;Lisa A. Chakrabarti

  • HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.

    Benoît Vingert;Santiago Perez-Patrigeon;Patricia Jeannin;Olivier Lambotte;Olivier Lambotte

  • Isotype regulation of antibody production: T-cell hybrids can be selectively induced to produce IgG1 and IgG2 subclass-specific suppressive immunoglobulin-binding factors.

    Ilana Lowy;Colette Brezin;Catherine Neauport-Sautes;Jacques Theze

  • NK cells and polymorphonuclear neutrophils are both critical for IL-2-induced pulmonary vascular leak syndrome.

    Eric Assier;Valérie Jullien;Jean Lefort;Jean-Louis Moreau

  • Regulatory dysfunction of the interleukin-2 receptor during HIV infection and the impact of triple combination therapy

    Denis David;Lynda Bani;Jean-Louis Moreau;Marie-Pierre Treilhou

  • HIV Controllers Maintain a Population of Highly Efficient Th1 Effector Cells in Contrast to Patients Treated in the Long Term

    Benoît Vingert;Daniela Benati;Olivier Lambotte;Pierre de Truchis

  • Antigen-specific T-cell-mediated suppression. I. Induction of L-glutamic acid(60)-L-alanine(30)-L-tyrosine(10) specific suppressor T cells in vitro requires both antigen-specific T-cell-suppressor factor and antigen

    RN Germain;J Theze;JA Kapp;B Benacerraf

  • Somatic diversification in the heavy chain variable region genes expressed by human autoantibodies bearing a lupus-associated nephritogenic anti-DNA idiotype

    Christophe Demaison;Patricia Chastagner;Jacques Theze;Moncef Zouali

  • Further characterization of the binding of human recombinant interleukin 2 to heparin and identification of putative binding sites

    Saloua Najjam;Barbara Mulloy;Jacques Theze;Myrtle Gordon

  • The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.

    P Ollier;J Rocca-Serra;G Sommé;J Thèze

  • Idiotypic Analysis of Anti-GAT Antibodies I. Presence of Common Idiotypic Specificities in Both Responder and Nonresponder Mice

    Shyr-Te Ju;Thomas J. Kipps;Jacques Theze;Baruj Benacerraf

  • Internalization of interleukin 2 (IL-2) by high affinity IL-2 receptors is required for the growth of IL-2-dependent T cell lines.

    A Kumar;J L Moreau;M Gibert;J Thèze

Frequent Co-Authors

Jean-François Delfraissy
Jean-François Delfraissy National Ethical Consultative Committee for Life Sciences and Health
Pedro M. Alzari
Pedro M. Alzari Institut Pasteur
Olivier Lambotte
Olivier Lambotte University of Paris-Saclay
Baruj Benacerraf
Baruj Benacerraf Harvard University
Michel E. Goldberg
Michel E. Goldberg Université Paris Cité
Marie-Lise Gougeon
Marie-Lise Gougeon Institut Pasteur
Bertrand Dupont
Bertrand Dupont Necker-Enfants Malades Hospital
Salem Chouaib
Salem Chouaib Gulf Medical University
Jerome Ritz
Jerome Ritz Harvard University
Christine Petit
Christine Petit Université Paris Cité

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