World's Best Scientists 2026 revealed!
Patrick England

Patrick England

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
10805
World Ranking
15613
National Ranking
632

Overview

Patrick England is affiliated with the Institut Pasteur in France, contributing to extensive research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans various subfields including Molecular Biology, Infectious Diseases, Public Health, Environmental and Occupational Health, Biomedical Engineering, and Radiology, Nuclear Medicine and Imaging.

The scientist's research addresses topics such as Mosquito-borne diseases and control, Enzyme Structure and Function, Malaria Research and Control, Monoclonal and Polyclonal Antibodies Research, Bacterial Genetics and Biotechnology, Clostridium difficile and Clostridium perfringens research, and Advanced biosensing and bioanalysis techniques.

Patrick England has published in prominent scientific journals, with multiple papers appearing in venues like bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, European Biophysics Journal, Nature Biotechnology, and ChemBioChem.

Selected recent publications include:

  • High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics (2020, Nature Biotechnology)
  • SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system (2021, Nature Communications)
  • SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction (2021, Nucleic Acids Research)
  • The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses (2021, Cell)
  • Dengue virus NS1 protein conveys pro-inflammatory signals by docking onto high-density lipoproteins (2022, EMBO Reports)

Collaborations feature several frequent co-authors who have worked closely with Patrick England on multiple publications. These include Bruno Iannascoli and Pierre Bruhns, each with 11 joint works, Ahmed Haouz with 10, Bertrand Raynal with 9, and F.A. Rey with 7 co-authored papers.

Best Publications

  • Specificity and affinity of human Fcγ receptors and their polymorphic variants for human IgG subclasses

    Pierre Bruhns;Pierre Bruhns;Bruno Iannascoli;Bruno Iannascoli;Patrick England;Patrick England;David A. Mancardi;David A. Mancardi

  • Structural basis of potent Zika–dengue virus antibody cross-neutralization

    Giovanna Barba-Spaeth;Wanwisa Dejnirattisai;Alexander Rouvinski;Marie Christine Vaney

  • Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

    Roland Hjerpe;Fabienne Aillet;Fernando Lopitz‐Otsoa;Valerie Lang

  • ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity

    Marien I. de Jonge;Gérard Pehau-Arnaudet;Marjan M. Fretz;Felix Romain

  • Clostridium difficile toxin expression is inhibited by the novel regulator TcdC

    Susana Matamouros;Patrick England;Bruno Dupuy

  • The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule.

    Thomas Krey;Jacques d'Alayer;Carlos M. Kikuti;Aure Saulnier

  • High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics

    Annabelle Gérard;Adam Woolfe;Guillaume Mottet;Marcel Reichen

  • Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring.

    Klaus Eyer;Raphaël C L Doineau;Carlos E Castrillon;Carlos E Castrillon;Luis Briseño-Roa

  • AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

    Cédric Artus;Cédric Artus;Cédric Artus;Hanan Boujrad;Hanan Boujrad;Hanan Boujrad;Ada Bouharrour;Ada Bouharrour;Ada Bouharrour;Marie Noëlle Brunelle;Marie Noëlle Brunelle;Marie Noëlle Brunelle

  • Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential

    Annemarie Wehenkel;Marco Bellinzoni;Martin Graña;Rosario Duran

  • Transglutaminase is essential for IgA nephropathy development acting through IgA receptors

    Laureline Berthelot;Christina Papista;Christina Papista;Thiago T. Maciel;Thiago T. Maciel;Martine Biarnes-Pelicot;Martine Biarnes-Pelicot

  • Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

    A Villarino;R. Duran;A. Wehenkel;P. Fernandez

  • Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

    Anand Srivastava;Stéphane Gangnard;Adam Round;Sébastien Dechavanne

  • The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy.

    David A. Mancardi;David A. Mancardi;Marcello Albanesi;Friederike Jönsson;Friederike Jönsson;Bruno Iannascoli;Bruno Iannascoli

  • FcγRIV is a mouse IgE receptor that resembles macrophage FcεRI in humans and promotes IgE-induced lung inflammation

    David A. Mancardi;Bruno Iannascoli;Sylviane Hoos;Patrick England

  • Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3

    Bogdan Mateescu;Patrick England;Frederic Halgand;Moshe Yaniv

  • Attenuation of Rabies Virulence: Takeover by the Cytoplasmic Domain of Its Envelope Protein

    Christophe Préhaud;Nicolas Wolff;Elouan Terrien;Mireille Lafage

  • A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients

    Ivan C Moura;Yves Lepelletier;Bertrand Arnulf;Patrick England

  • Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids

    Amel Bahloul;Amel Bahloul;Amel Bahloul;Vincent Michel;Vincent Michel;Vincent Michel;Jean-Pierre Hardelin;Jean-Pierre Hardelin;Jean-Pierre Hardelin;Sylvie Nouaille;Sylvie Nouaille;Sylvie Nouaille

  • Single-domain antibodies recognize selectively small oligomeric forms of amyloid beta, prevent Abeta-induced neurotoxicity and inhibit fibril formation.

    Pierre Lafaye;Ikbel Achour;Patrick England;Charles Duyckaerts

Frequent Co-Authors

Félix A. Rey
Félix A. Rey Institut Pasteur
Pierre Bruhns
Pierre Bruhns Université Paris Cité
Vincent Goffin
Vincent Goffin Université Paris Cité
Andréa Dessen
Andréa Dessen Brazilian Biosciences National Laboratory
Anne Houdusse
Anne Houdusse Université Paris Cité
Pedro M. Alzari
Pedro M. Alzari Institut Pasteur
Christine Ebel
Christine Ebel Grenoble Alpes University
Birthe B. Kragelund
Birthe B. Kragelund University of Copenhagen
Marc Daëron
Marc Daëron Institut Pasteur
Anthony P. Pugsley
Anthony P. Pugsley Institut Pasteur

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