World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
15525
World Ranking
1521
National Ranking
1

Research.com Recognitions

  • 2006 - Member of the National Academy of Sciences
  • 2001 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Alberto C.C. Frasch is affiliated with the National University of General San Martín in Argentina. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with particular emphasis on Molecular Biology and Cell Biology. Additional subfields of their work include Aging, Physiology, and Behavioral Neuroscience.

The scientist's work spans several topics including:

  • Genetics, Aging, and Longevity in Model Organisms
  • Mitochondrial Function and Pathology
  • Cellular transport and secretion
  • Signaling Pathways in Disease
  • Caveolin-1 and cellular processes
  • Salivary Gland Disorders and Functions
  • S100 Proteins and Annexins

Alberto C.C. Frasch has authored or coauthored research papers published in peer-reviewed journals such as the Journal of Neurochemistry, Frontiers in Synaptic Neuroscience, and the Journal of Affective Disorders Reports. Notable recent publications include:

  • Identification of Potential Interacting Proteins With the Extracellular Loops of the Neuronal Glycoprotein M6a by TMT/MS (2020, Frontiers in Synaptic Neuroscience)
  • Search of brain-enriched proteins in salivary extracellular vesicles for their use as mental disease biomarkers: A pilot study of the neuronal glycoprotein M6a (2020, Journal of Affective Disorders Reports)
  • Neuronal membrane glycoprotein (nmgp-1) gene deficiency affects chemosensation-related behaviors, dauer exit and egg-laying in Caenorhabditis elegans (2021, Journal of Neurochemistry)

Frequent collaborators with whom Alberto C.C. Frasch has coauthored multiple papers include Melisa C. Monteleone, Marcela A. Brocco, Eliana M. Fernández, Yamila B. Cutraro, and Jessica M. Adams.

The scientist has been recognized with distinctions such as becoming a Member of the National Academy of Sciences in 2006 and being named a Fellow of the John Simon Guggenheim Memorial Foundation in 2001.

Best Publications

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • The genome of the kinetoplastid parasite, Leishmania major.

    Alasdair C. Ivens;Christopher S. Peacock;Elizabeth A. Worthey;Lee Murphy

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

  • Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi.

    A.C.C Frasch

  • Trypanosoma cruzi surface mucins: host-dependent coat diversity

    Carlos A. Buscaglia;Vanina A. Campo;Alberto C. C. Frasch;Javier M. Di Noia;Javier M. Di Noia

  • Novel expression-linked copies of the genes for variant surface antigens in trypanosomes.

    Jan Hoeijmakers;A.C.C. Frasch;André Bernards;Piet Borst

  • The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis

    Alejandro Buschiazzo;Marı́a F. Amaya;Marı́a L. Cremona;Alberto C. Frasch

  • Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.

    M.F Amaya;A.G Watts;I Damager;A Wehenkel

  • The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes.

    O. Campetella;J. Henriksson;U. Åslund;A.C.C. Frasch

  • Regulation of hippocampal gene expression is conserved in two species subjected to different stressors and antidepressant treatments.

    Julieta Alfonso;Luciana R. Frick;Dafne M. Silberman;María L. Palumbo

  • Identification of a Trypanosoma cruzi antigen that is shed during the acute phase of Chagas' disease.

    JoséL. Affranchino;Carlos F. Ibañez;Alejandro O. Luquetti;Anis Rassi

  • Multiple Trypanosoma cruzi antigens containing tandemly repeated amino acid sequence motifs.

    Carlos F. Ibañez;Jose L. Affranchino;Roberto A. Macina;Maria B. Reyes

  • A Trypanosoma cruzi Small Surface Molecule Provides the First Immunological Evidence that Chagas' Disease Is Due to a Single Parasite Lineage

    Javier M. Di Noia;Carlos A. Buscaglia;Claudia R. De Marchi;Igor C. Almeida

  • AU-rich elements in the 3'-untranslated region of a new mucin-type gene family of Trypanosoma cruzi confers mRNA instability and modulates translation efficiency

    Javier M. Di Noia;Iván D'Orso;Daniel O. Sánchez;Alberto C.C. Frasch

  • RNA-Binding Domain Proteins in Kinetoplastids: a Comparative Analysis

    Javier De Gaudenzi;Alberto C. Frasch;Christine Clayton

  • Comparison of the genes coding for the common 5′ terminal sequence of messenger RNAs in three trypanosome species

    Titia De Lange;Theo M. Berkvens;Harry J.G. Veerman;A.Carlos C. Frasch

  • Structural basis of sialyltransferase activity in trypanosomal sialidases.

    Alejandro Buschiazzo;Gisele A. Tavares;Gisele A. Tavares;Oscar Campetella;Silvia Spinelli

  • Recruitment of mRNAs to cytoplasmic ribonucleoprotein granules in trypanosomes

    Alejandro Cassola;Javier G. De Gaudenzi;Alberto C. Frasch

  • Identification of genes regulated by chronic psychosocial stress and antidepressant treatment in the hippocampus.

    Julieta Alfonso;Guido D. Pollevick;Marieke G. Van Der Hart;Gabriele Flügge

  • A single tyrosine differentiates active and inactive Trypanosoma cruzi trans-sialidases

    Maria L. Cremona;Daniel O. Sánchez;Alberto C.C. Frasch;Oscar Campetella

Frequent Co-Authors

Ulf Pettersson
Ulf Pettersson Uppsala University
Juan José Cazzulo
Juan José Cazzulo National University of General San Martín
Pedro M. Alzari
Pedro M. Alzari Institut Pasteur
Igor C. Almeida
Igor C. Almeida The University of Texas at El Paso
Kenneth Stuart
Kenneth Stuart University of Washington
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Roberto Docampo
Roberto Docampo University of Georgia
Mariano J. Levin
Mariano J. Levin University of Buenos Aires
Christine Clayton
Christine Clayton Heidelberg University
Jessica C. Kissinger
Jessica C. Kissinger University of Georgia

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