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Biology and Biochemistry
UK
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
41031
World Ranking
2281
National Ranking
154

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award

Overview

Graham H. Coombs is affiliated with the University of Strathclyde in the United Kingdom. Their research primarily focuses on the field of Medicine, with substantial work in several related subfields including Pharmacology, Public Health, Environmental and Occupational Health, Biochemistry, Human-Computer Interaction, and Management of Technology and Innovation.

The scientist's research topics cover a broad spectrum, with notable emphasis on:

  • Biochemical Acid Research Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Malaria Research and Control
  • Pharmaceutical Industry and Healthcare
  • Clinical Practice Guidelines Implementation
  • Ethics in Clinical Research
  • Innovative Human-Technology Interaction

Graham H. Coombs has published in several academic venues, including:

  • International Journal for Parasitology
  • Drug Safety
  • The Design Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent papers authored or co-authored by Coombs span from 2020 to 2024 and include:

  • Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes, 2021, International Journal for Parasitology
  • Views on the Development and Use of a New Digital Adverse Drug Event Reporting Platform in Australia: A Qualitative Study, 2024, Drug Safety
  • Sequenced co-design with stakeholder communities to support the development of spaces for mental health recovery and healing, 2024, The Design Journal
  • Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in their work include:

  • Marco Biddau
  • T. R. Santha Kumar
  • Philipp P. Henrich
  • Larissa Laine
  • Gavin Blackburn

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Leishmaniasis– current chemotherapy and recent advances in the search for novel drugs

    Simon L. Croft;Graham H. Coombs

  • Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    Jane M. Carlton;Robert . Hirt;Joana C. Silva;Arthur L. Delcher

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Evidence for the shikimate pathway in apicomplexan parasites

    Fiona Roberts;Fiona Roberts;Craig W. Roberts;Jennifer J. Johnson;Dennis E. Kyle

  • Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

    Tim Downing;Hideo Imamura;Saskia Decuypere;Taane G. Clark

  • Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii

    Peter J. Bradley;Peter J. Bradley;Chris Ward;Stephen J. Cheng;David L. Alexander

  • Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets

    Graham H. Coombs;Daniel E. Goldberg;Michael Klemba;Colin Berry

  • Leishmania mexicana Cysteine Proteinase-Deficient Mutants Have Attenuated Virulence for Mice and Potentiate a Th1 Response

    James Alexander;Graham H. Coombs;Jeremy C. Mottram

  • Cysteine peptidases as virulence factors of Leishmania

    Jeremy C Mottram;Graham H Coombs;James Alexander

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

    J C Mottram;A E Souza;J E Hutchison;R Carter

  • Non-ionic surfactant vesicles, niosomes, as a delivery system for the anti-leishmanial drug, sodium stibogluconate.

    A J Baillie;G H Coombs;T F Dolan;J Laurie

  • Axenic cultivation and characterization of Leishmania mexicana amastigote-like forms.

    P. A. Bates;C. D. Robertson;L. Tetley;G. H. Coombs

  • Endosome Sorting and Autophagy Are Essential for Differentiation and Virulence of Leishmania major

    Sébastien Besteiro;Roderick A.M. Williams;Lesley S. Morrison;Graham H. Coombs

  • Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose.

    Nadia Lamour;Loïc Rivière;Virginie Coustou;Graham H. Coombs

  • The shikimate pathway and its branches in apicomplexan parasites.

    Craig W. Roberts;Fiona Roberts;Russell E. Lyons;Michael J. Kirisits

  • Vesicular systems (niosomes and liposomes) for delivery of sodium stibogluconate in experimental murine visceral leishmaniasis.

    C A Hunter;T F Dolan;G H Coombs;A J Baillie

  • Metabolism of Leishmania : proven and predicted

    Frederik Opperdoes;Graham H Coombs

Frequent Co-Authors

Jeremy C. Mottram
Jeremy C. Mottram University of York
Luiz Juliano
Luiz Juliano Federal University of Sao Paulo
Sylke Müller
Sylke Müller University of Glasgow
Maria A. Juliano
Maria A. Juliano Federal University of Sao Paulo
Jean-Claude Dujardin
Jean-Claude Dujardin Institute of Tropical Medicine Antwerp
James Alexander
James Alexander Centers for Disease Control and Prevention
Morten Meldal
Morten Meldal University of Copenhagen
David G. Watson
David G. Watson University of Strathclyde
Rainer Breitling
Rainer Breitling University of Manchester
Michael P. Barrett
Michael P. Barrett University of Glasgow

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