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Biology and Biochemistry

D-Index
53
Citations
17188
World Ranking
15925
National Ranking
1253

Overview

Sylke Müller is affiliated with the University of Glasgow in the United Kingdom. Their research spans several areas within medicine and biochemistry, with a focus on biochemical acid research studies, cholinesterase and neurodegenerative diseases, malaria research and control, and the role of tryptophan in brain disorders.

Their work has been published in various venues including the International Journal for Parasitology and bioRxiv (Cold Spring Harbor Laboratory). Notable recent papers include:

  • Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes, 2021, International Journal for Parasitology
  • Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Their research fields encompass Medicine and Biochemistry, Genetics, and Molecular Biology. Within these, subfields of study include biochemistry, pharmacology, public health, environmental and occupational health, and biological psychiatry.

Frequent coauthors collaborating with Sylke Müller include Marco Biddau, T. R. Santha Kumar, Philipp P. Henrich, Larissa Laine, and Gavin Blackburn.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    Jane M. Carlton;Robert . Hirt;Joana C. Silva;Arthur L. Delcher

  • Thioredoxin reductase as a pathophysiological factor and drug target

    Katja Becker;Stephan Gromer;R. Heiner Schirmer;Sylke Müller

  • Complete Dna-Sequence Of Yeast Chromosome-Xi

    B. Dujon;D. Alexandraki;B. André;W. Ansorge

  • Thioredoxin reductase two modes of catalysis have evolved.

    C H Williams;L D Arscott;S Müller;B W Lennon

  • Redox and antioxidant systems of the malaria parasite Plasmodium falciparum

    Sylke Müller

  • Thiol-based redox metabolism of protozoan parasites

    Sylke Müller;Eva Liebau;Rolf D. Walter;R.Luise Krauth-Siegel

  • Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle

    Christine R Collins;Sujaan Das;Eleanor H Wong;Nicole Andenmatten

  • Targeting polyamines of parasitic protozoa in chemotherapy.

    Sylke Müller;Graham H. Coombs;Rolf D. Walter

  • Therapeutic vaccination of HIV-1-infected patients on HAART with a recombinant HIV-1 nef-expressing MVA: safety, immunogenicity and influence on viral load during treatment interruption.

    Harrer E;Bäuerle M;Ferstl B;Chaplin P

  • Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages.

    Zita Krnajski;Tim-Wolf Gilberger;Tim-Wolf Gilberger;Rolf D. Walter;Alan F. Cowman

  • Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum

    Svenja Meierjohann;Rolf D Walter;Sylke Müller;Sylke Müller

  • The diversity and evolution of thioredoxin reductase: new perspectives.

    Robert P. Hirt;Sylke Müller;T. Martin Embley;Graham H. Coombs

  • Plasmodium falciparum-infected red blood cells depend on a functional glutathione de novo synthesis attributable to an enhanced loss of glutathione.

    Kai Lüersen;Rolf D. Walter;Sylke Müller

  • 3-Aminooxy-1-Aminopropane and Derivatives Have an Antiproliferative Effect on Cultured Plasmodium falciparum by Decreasing Intracellular Polyamine Concentrations

    Robin Das Gupta;Tanja Krause-Ihle;Bärbel Bergmann;Ingrid B. Müller

  • In the Human Malaria Parasite Plasmodium falciparum,Polyamines Are Synthesized by a Bifunctional Ornithine Decarboxylase,S-Adenosylmethionine Decarboxylase

    Sylke Müller;Akram Da'dara;Kai Lüersen;Carsten Wrenger

  • Molecular Mechanisms of Drug Resistance in Natural Leishmania Populations Vary with Genetic Background

    Saskia Decuypere;Manu Vanaerschot;Kirstyn Brunker;Hideo Imamura;Hideo Imamura

  • The amitochondriate eukaryote Trichomonas vaginalis contains a divergent thioredoxin-linked peroxiredoxin antioxidant system.

    Graham H. Coombs;Gareth D. Westrop;Pavel Suchan;Gabriela Puzova

  • IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II.

    Jeralyn D. Haraldsen;Gu Liu;Catherine H. Botting;Jeffrey G. A. Walton

  • The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases

    Paul J. McMillan;Luciana M. Stimmler;Bernardo J. Foth;Geoffrey I. McFadden

Frequent Co-Authors

Graham H. Coombs
Graham H. Coombs University of Strathclyde
Katja Becker
Katja Becker University of Giessen
R. Heiner Schirmer
R. Heiner Schirmer Heidelberg University
Alan H. Fairlamb
Alan H. Fairlamb University of Dundee
Michael P. Barrett
Michael P. Barrett University of Glasgow
Irmgard Sinning
Irmgard Sinning Heidelberg University
Geoffrey I. McFadden
Geoffrey I. McFadden University of Melbourne
Christian Doerig
Christian Doerig RMIT University
Jeremy C. Mottram
Jeremy C. Mottram University of York
T. Martin Embley
T. Martin Embley Newcastle University

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