R. Heiner Schirmer

Overview

Best Publications

• Principles of Protein Structure

  Georg E. Schulz;R. Heiner Schirmer

  2013
  Citations

• Human Placenta Thioredoxin Reductase: ISOLATION OF THE SELENOENZYME, STEADY STATE KINETICS, AND INHIBITION BY THERAPEUTIC GOLD COMPOUNDS *

  Stephan Gromer;L. David Arscott;Charles H. Williams;R. Heiner Schirmer

  639
  Citations

• Substitution of the Thioredoxin System for Glutathione Reductase in Drosophila melanogaster

  Stefan M. Kanzok;Stefan M. Kanzok;Anke Fechner;Anke Fechner;Holger Bauer;Julia K. Ulschmid

  498
  Citations

• Thioredoxin reductase as a pathophysiological factor and drug target

  Katja Becker;Stephan Gromer;R. Heiner Schirmer;Sylke Müller

  495
  Citations

• "Lest we forget you--methylene blue...".

  R. Heiner Schirmer;Heike Adler;Marcus Pickhardt;Eckhard Mandelkow

  449
  Citations

• Thioredoxin reductase two modes of catalysis have evolved.

  C H Williams;L D Arscott;S Müller;B W Lennon

  423
  Citations

• Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia.

  R. Luise Krauth-Siegel;Holger Bauer;R. Heiner Schirmer

  413
  Citations

• The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli

  L. David Arscott;Stephan Gromer;R. Heiner Schirmer;Katja Becker

  317
  Citations

• The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited

  S M Kanzok;R H Schirmer;I Turbachova;R Iozef

  303
  Citations

• Disulfide‐Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

  R. Heiner Schirmer;Joachim G. Müller;R. Luise Krauth‐Siegel

  299
  Citations

• Methylene blue as an antimalarial agent.

  R. Heiner Schirmer;Boubacar Coulibaly;August Stich;Michael Scheiwein

  282
  Citations

• Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme.

  R. Luise Krauth-Siegel;Burkhard Enders;Graeme B. Henderson;Alan H. Fairlamb

  263
  Citations

• Glutathione reductase from human erythrocytes. The sequences of the NADPH domain and of the interface domain.

  R. Luise Krauth-Siegel;Mansoor Saleh;Renate Untucht-Grau;R. Heiner Schirmer

  262
  Citations

• Active sites of thioredoxin reductases: Why selenoproteins?

  Stephan Gromer;Linda Johansson;Holger Bauer;L. David Arscott

  250
  Citations

• The Amino‐Acid Sequence of Porcine Adenylate Kinase from Skeletal Muscle

  Albert Heil;Gudrun Müller;Lafayette Noda;Thomas Pinder

  241
  Citations

• Synthetic Inhibitors of Adenylate Kinases in the Assays for ATPases and Phosphokinases

  Peter Feldhaus;Thomas Fröhlich;Roger S. Goody;Maria Isakov

  222
  Citations

• Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum.

  Kathrin Buchholz;R. Heiner Schirmer;Jana K. Eubel;Monique B. Akoachere

  199
  Citations

• Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers

  K Becker;Savvas Savvides;M Keese;Rh Schirmer

  191
  Citations

• Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue.

  P.M Färber;L.D Arscott;C.H Williams;K Becker

  189
  Citations

• Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor Strategy

  Katja Becker;Christel Herold-Mende;Jenny J. Park;Gordon Lowe

  181
  Citations