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Govindasamy Mugesh

Govindasamy Mugesh

D-Index & Metrics

Chemistry

D-Index
56
Citations
13752
World Ranking
11480
National Ranking
179

Overview

Govindasamy Mugesh is affiliated with the Indian Institute of Science in India. Their research primarily spans the fields of Materials Science and Biochemistry, Genetics and Molecular Biology, with significant contributions also in subfields such as Materials Chemistry, Molecular Biology, Endocrinology, Diabetes and Metabolism, Physiology, and Organic Chemistry.

The scientist's work addresses diverse topics including:

  • Advanced Nanomaterials in Catalysis
  • Nanocluster Synthesis and Applications
  • Nanoparticles: synthesis and applications
  • Thyroid Disorders and Treatments
  • Sulfur Compounds in Biology
  • Vanadium and Halogenation Chemistry
  • Organoselenium and organotellurium chemistry

Govindasamy Mugesh has contributed articles to a variety of scientific journals, frequently publishing in:

  • Angewandte Chemie
  • Chemistry - A European Journal
  • Angewandte Chemie International Edition
  • ACS Applied Bio Materials
  • Oncogene

Selected recent papers include:

  • A Cerium Vanadate Nanozyme with Specific Superoxide Dismutase Activity Regulates Mitochondrial Function and ATP Synthesis in Neuronal Cells, 2020, Angewandte Chemie International Edition
  • Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next-Generation Therapeutics, 2023, Angewandte Chemie International Edition
  • Nanoceria-Based Phospholipase-Mimetic Cell Membrane Disruptive Antibiofilm Agents, 2020, ACS Applied Bio Materials
  • Antioxidant nanozyme counteracts HIV-1 by modulating intracellular redox potential, 2021, EMBO Molecular Medicine
  • Platelet activation and ferroptosis mediated NETosis drives heme induced pulmonary thrombosis, 2023, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Their frequent collaborators include:

  • Debasish Giri
  • Somanathapura K. NaveenKumar
  • Namrata Singh
  • G. R. Sherin
  • Sourav Ghosh

Best Publications

  • Chemistry of biologically important synthetic organoselenium compounds.

    Mugesh G;du Mont Ww;Sies H

  • Synthetic organoselenium compounds as antioxidants:glutathione peroxidase activity

    Govindasamy Mugesh;Harkesh B. Singh

  • Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidants.

    Krishna P Bhabak;Govindasamy Mugesh

  • A Redox Modulatory Mn3O4 Nanozyme with Multi-Enzyme Activity Provides Efficient Cytoprotection to Human Cells in a Parkinson's Disease Model

    Namrata Singh;Mohammed Azharuddin Savanur;Shubhi Srivastava;Patrick D'Silva

  • An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

    Amit A Vernekar;Devanjan Sinha;Shubhi Srivastava;Prasath U Paramasivam

  • Glutathione peroxidase-like antioxidant activity of diaryl diselenides: a mechanistic study.

    G. Mugesh;Arunashree Panda;Harkesh B. Singh;Narayan S. Punekar

  • Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions.

    Bani Kanta Sarma;G Mugesh

  • Nanoisozymes: Crystal-Facet-Dependent Enzyme-Mimetic Activity of V2 O5 Nanomaterials.

    Sourav Ghosh;Punarbasu Roy;Naiwrit Karmodak;Eluvathingal D. Jemmis

  • Synthesis, characterization, and antioxidant activity of some ebselen analogues.

    Krishna P. Bhabak;Govindasamy Mugesh

  • Chemistry and Biology in the Biosynthesis and Action of Thyroid Hormones

    Santanu Mondal;Karuppusamy Raja;Ulrich Schweizer;Govindasamy Mugesh

  • Antioxidant activity of the anti-inflammatory compound ebselen: a reversible cyclization pathway via selenenic and seleninic acid intermediates.

    Bani Kanta Sarma;Govindasamy Mugesh

  • Vacancy-Engineered Nanoceria: Enzyme Mimetic Hotspots for the Degradation of Nerve Agents.

    Amit A. Vernekar;Tandrila Das;Govindasamy Mugesh

  • Heteroatom-directed aromatic lithiation: a versatile route to the synthesis of organochalcogen (Se, Te) compounds.

    Govindasamy Mugesh;Harkesh B Singh

  • Antithyroid Drugs and Their Analogues: Synthesis, Structure, and Mechanism of Action

    Debasish Manna;Gouriprasanna Roy;Govindasamy Mugesh

  • Synthesis, structure, spirocyclization mechanism, and glutathione peroxidase-like antioxidant activity of stable spirodiazaselenurane and spirodiazatellurane.

    Bani Kanta Sarma;Debasish Manna;Mao Minoura;Govindasamy Mugesh

  • Structure–Activity Correlation between Natural Glutathione Peroxidase (GPx) and Mimics: A Biomimetic Concept for the Design and Synthesis of More Efficient GPx Mimics

    Govindasamy Mugesh;Wolf-Walther du Mont

  • A Cerium Vanadate Nanozyme with Specific Superoxide Dismutase Activity Regulates Mitochondrial Function and ATP Synthesis in Neuronal Cells

    Namrata Singh;Somanathapura K. NaveenKumar;Motika Geethika;Govindasamy Mugesh

  • Anticancer property of Bryophyllum pinnata (Lam.) Oken. leaf on human cervical cancer cells

    Sutapa Mahata;Saurabh Maru;Shirish Shukla;Arvind Pandey

  • Regioselective Deiodination of Thyroxine by Iodothyronine Deiodinase Mimics: An Unusual Mechanistic Pathway Involving Cooperative Chalcogen and Halogen Bonding

    Debasish Manna;Govindasamy Mugesh

  • Intramolecular Se⋅⋅⋅N Nonbonding Interactions in Low‐Valent Organoselenium Derivatives: A Detailed Study by 1H and 77Se NMR Spectroscopy and X‐ray Crystallography

    G. Mugesh;Arunashree Panda;Harkesh B. Singh;Ray J. Butcher

  • Thiol cofactors for selenoenzymes and their synthetic mimics

    Bani Kanta Sarma;Govindasamy Mugesh

Frequent Co-Authors

Harkesh B. Singh
Harkesh B. Singh Indian Institute of Technology Bombay
Ray J. Butcher
Ray J. Butcher Howard University
Peter G. Jones
Peter G. Jones Technische Universität Braunschweig
Munirathinam Nethaji
Munirathinam Nethaji Indian Institute of Science
Ulrich Schweizer
Ulrich Schweizer University of Bonn
Helmut Sies
Helmut Sies Heinrich Heine University Düsseldorf
Vito Lippolis
Vito Lippolis University of Cagliari
Eluvathingal D. Jemmis
Eluvathingal D. Jemmis Indian Institute of Science
Eduardo R. Lazarowski
Eduardo R. Lazarowski University of North Carolina at Chapel Hill
Thomas Wirth
Thomas Wirth Cardiff University

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