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D-Index & Metrics

Immunology

D-Index
81
Citations
18408
World Ranking
1591
National Ranking
794

Overview

James Alexander is affiliated with the Centers for Disease Control and Prevention in the United States. Their research spans several interconnected fields, primarily focused on Biochemistry, Genetics and Molecular Biology, with significant contributions to Immunology and Microbiology.

Their work prominently covers subfields such as Genetics, Immunology, and Pathology and Forensic Medicine. The research topics include Genetics and Neurodevelopmental Disorders, Genomic Variations and Chromosomal Abnormalities, Genomics and Rare Diseases, T-cell and B-cell Immunology, Immunodeficiency and Autoimmune Disorders, and Biomedical Research and Pathophysiology.

James Alexander has published multiple papers in recognized venues, contributing to the advancement of knowledge within their areas of expertise. Their recent publications include:

  • EVALUATING GENE REPLACEMENT THERAPY FOR CTNNB1 HAPLOINSUFFICIENCY, 2025, Cytotherapy
  • Spatial Dynamics of γMSC-T Cell Interactions and Their Role in GVHD Prophylaxis, 2025, Cytotherapy
  • O44 Nurse-led clinic (NLC) to expedite pathway for ophthalmology screening of IBD patients prior to treatment with sphingosine-1-phosphate receptor (S1PR) modulators, 2025, Oral Presentations

Their frequent coauthors are:

  • Lydie Tessier
  • Michele H. Jacob
  • Swathi Shrihari
  • Elisabetta Manuela Foppiani
  • Jennifer Okáľová

James Alexander's research has been published predominantly in the journal Cytotherapy and in Oral Presentations formats. Their body of work reflects a consistent focus on the intersection of molecular biology and immunological mechanisms, addressing complex biomedical challenges such as gene therapy, immune cell dynamics, and clinical pathways for screening and treatment.

Best Publications

  • Deaths of Children during an Outbreak of Hand, Foot, and Mouth Disease in Sarawak, Malaysia: Clinical and Pathological Characteristics of the Disease

    L. G. Chan;Umesh D. Parashar;M. S. Lye;F. G. L. Ong

  • Sex-Associated Hormones and Immunity to Protozoan Parasites

    Craig W. Roberts;William Walker;James Alexander

  • Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling

    James M. Brewer;Margaret Conacher;Christopher A. Hunter;Markus Mohrs

  • Sex hormones and the course of parasitic infection

    J. Alexander;W.H. Stimson

  • Leishmania species: models of intracellular parasitism.

    J. Alexander;A.R. Satoskar;D.G. Russell

  • The interaction of Leishmania species with macrophages.

    James Alexander;David G. Russell

  • Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease

    Diane McMahon-Pratt;James Alexander

  • Progress Toward Regional Measles Elimination - Worldwide, 2000-2019.

    Minal K. Patel;James L. Goodson;James P. Alexander;Katrina Kretsinger

  • CD4+CD25+ Regulatory T Cells Suppress Differentiation and Functions of Th1 and Th2 Cells, Leishmania major Infection, and Colitis in Mice

    Damo Xu;Haiying Liu;Mousa Komai-Koma;Carol Campbell

  • T helper (h)1/Th2 and Leishmania: paradox rather than paradigm.

    James Alexander;Karen Bryson

  • Leishmania mexicana Cysteine Proteinase-Deficient Mutants Have Attenuated Virulence for Mice and Potentiate a Th1 Response

    James Alexander;Graham H. Coombs;Jeremy C. Mottram

  • Cysteine peptidases as virulence factors of Leishmania

    Jeremy C Mottram;Graham H Coombs;James Alexander

  • In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to freund's complete adjuvant, but continues to induce T helper 2 cytokine production.

    James M. Brewer;Margaret Conacher;Abhay Satoskar;Horst Bluethmann

  • Neuropsychiatric Disease and Toxoplasma gondii Infection

    S.A. Henriquez;Ros Brett;J. Alexander;Judith Pratt

  • Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.

    Simona Stäger;James Alexander;Alun C Kirby;Marina Botto

  • Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes)

    Margaret Conacher;James Alexander;James M. Brewer

  • CD8+ T cells are the major lymphocyte subpopulation involved in the protective immune response to Toxoplasma gondii in mice.

    S J Parker;C W Roberts;J Alexander

  • Effective immunization against cutaneous leishmaniasis with defined membrane antigens reconstituted into liposomes.

    Unknown

  • Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

    Pamela Cameron;Adrienne McGachy;Mary Anderson;Andrew Paul

  • Lipid Vesicle Size Determines the Th1 or Th2 Response to Entrapped Antigen

    James M. Brewer;Laurence Tetley;James Richmond;Foo Y. Liew

  • T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction.

    P Garside;M Steel;E A Worthey;A Satoskar

  • Progress Toward Regional Measles Elimination — Worldwide, 2000–2017

    Alya Dabbagh;Rebecca L. Laws;Claudia Steulet;Laure Dumolard

Frequent Co-Authors

Craig W. Roberts
Craig W. Roberts University of Strathclyde
James M. Brewer
James M. Brewer University of Glasgow
Abhay R. Satoskar
Abhay R. Satoskar The Ohio State University
Frank Brombacher
Frank Brombacher University of Cape Town
Jeremy C. Mottram
Jeremy C. Mottram University of York
Graham H. Coombs
Graham H. Coombs University of Strathclyde
Robin Plevin
Robin Plevin University of Strathclyde
Mark A. Pallansch
Mark A. Pallansch National Center for Immunization and Respiratory Diseases
Horst Bluethmann
Horst Bluethmann Roche (Switzerland)
Foo Y. Liew
Foo Y. Liew University of Glasgow

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