H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 42 Citations 6,352 127 World Ranking 3440 National Ranking 283

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

His scientific interests lie mostly in Immunology, Phosphorylcholine, Immune system, Acanthocheilonema viteae and Cytokine. His Immunology study combines topics from a wide range of disciplines, such as Signal transduction and In vivo. His Phosphorylcholine research focuses on Cell biology and how it connects with Dendritic cell and Interleukin 12.

His Immune system research is multidisciplinary, relying on both Parasitic helminth, Ex vivo and Antigen. William Harnett combines subjects such as Receptor, Protein kinase C and Molecular biology, Glycoprotein with his study of Acanthocheilonema viteae. His Cytokine research integrates issues from Ovalbumin and TLR4.

His most cited work include:

  • A Filarial Nematode-Secreted Product Signals Dendritic Cells to Acquire a Phenotype That Drives Development of Th2 Cells (324 citations)
  • Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62 (203 citations)
  • A Novel Therapeutic Approach Targeting Articular Inflammation Using the Filarial Nematode-Derived Phosphorylcholine-Containing Glycoprotein ES-62 (183 citations)

What are the main themes of his work throughout his whole career to date?

William Harnett mainly focuses on Immunology, Acanthocheilonema viteae, Immune system, Phosphorylcholine and Biochemistry. His Antigen, Inflammation, Cytokine, Helminths and Arthritis investigations are all subjects of Immunology research. His studies examine the connections between Acanthocheilonema viteae and genetics, as well as such issues in Molecular biology, with regards to Epitope.

His research investigates the connection with Immune system and areas like Nematode which intersect with concerns in Host. His research in Phosphorylcholine intersects with topics in In vivo, TLR4, Glycoprotein and Cell biology. His work carried out in the field of Cell biology brings together such families of science as T cell and Dendritic cell.

He most often published in these fields:

  • Immunology (54.19%)
  • Acanthocheilonema viteae (33.50%)
  • Immune system (30.05%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (54.19%)
  • Acanthocheilonema viteae (33.50%)
  • Immune system (30.05%)

In recent papers he was focusing on the following fields of study:

His main research concerns Immunology, Acanthocheilonema viteae, Immune system, Helminths and Phosphorylcholine. Inflammation, Arthritis, Rheumatoid arthritis, Cytokine and Antigen are subfields of Immunology in which his conducts study. His Cytokine research is multidisciplinary, incorporating elements of Anti-nuclear antibody, In vivo and Cell biology.

The Acanthocheilonema viteae study combines topics in areas such as Microbiome, CD86, Calorie, Glycoprotein and Pharmacology. His Immune system research includes elements of Metabolic syndrome, Type 2 diabetes and Microfilaria. His Phosphorylcholine study is focused on Biochemistry in general.

Between 2012 and 2021, his most popular works were:

  • Secretory products of helminth parasites as immunomodulators. (96 citations)
  • Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced Arthritis (58 citations)
  • ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae (55 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

His primary areas of study are Immunology, Acanthocheilonema viteae, Arthritis, Inflammation and Immune system. William Harnett works mostly in the field of Immunology, limiting it down to topics relating to Helminth protein and, in certain cases, Bone marrow, as a part of the same area of interest. His Acanthocheilonema viteae research includes themes of Microbiome, Glycoprotein, Phosphorylcholine, Systemic lupus erythematosus and Pharmacology.

His study focuses on the intersection of Phosphorylcholine and fields such as Drug development with connections in the field of Mechanism of action. The various areas that he examines in his Inflammation study include Mast cell and Cell biology. His Adoptive cell transfer study in the realm of Immune system interacts with subjects such as Kidney metabolism.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Filarial Nematode-Secreted Product Signals Dendritic Cells to Acquire a Phenotype That Drives Development of Th2 Cells

Michael Whelan;Margaret M. Harnett;Katrina M. Houston;Vanshree Patel.
Journal of Immunology (2000)

505 Citations

Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62

Helen S. Goodridge;Fraser A. Marshall;Kathryn J. Else;Katrina M. Houston.
Journal of Immunology (2005)

270 Citations

Inhibition of FcεRI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

Alirio J. Melendez;Margaret M. Harnett;Peter N. Pushparaj;Ws Fred Wong.
Nature Medicine (2007)

253 Citations

A Novel Therapeutic Approach Targeting Articular Inflammation Using the Filarial Nematode-Derived Phosphorylcholine-Containing Glycoprotein ES-62

Iain B. McInnes;Bernard P. Leung;Margaret Harnett;J. Alastair Gracie.
Journal of Immunology (2003)

230 Citations

Helminth-derived immunomodulators: can understanding the worm produce the pill?

William Harnett;Margaret M. Harnett.
Nature Reviews Immunology (2010)

225 Citations

Phosphorylcholine: friend or foe of the immune system?

William Harnett;Margaret M Harnett.
Immunology Today (1999)

220 Citations

Increased exposure of parasite antigens at the surface of adult male Schistosoma mansoni exposed to praziquantel in vitro.

W. Harnett;J. R. Kusel.
Parasitology (1986)

171 Citations

Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses

Helen S Goodridge;William Harnett;Foo Y Liew;Margaret M Harnett.
Immunology (2003)

165 Citations

Inhibition of murine B cell proliferation and down-regulation of protein kinase C levels by a phosphorylcholine-containing filarial excretory-secretory product.

W Harnett;M M Harnett.
Journal of Immunology (1993)

155 Citations

Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology

Malcolm M. Kennedy;William Harnett.
Parasitic nematodes: molecular biology, biochemistry and immunology. (2001)

153 Citations

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