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Immunology

D-Index
56
Citations
8929
World Ranking
3761
National Ranking
333

Overview

William Harnett is affiliated with the University of Strathclyde in the United Kingdom. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with a strong emphasis on parasitology, molecular biology, and immunology. The main topics covered in their work include parasites and host interactions, research on leishmaniasis studies, gut microbiota and health, genetics, aging, and longevity in model organisms, dietary effects on health, immune responses and vaccinations, as well as epigenetics and DNA methylation.

Several frequent collaborators have contributed to William Harnett's work. These notable co-authors include:

  • Margaret M. Harnett
  • Felicity E. Lumb
  • James Doonan
  • Uk Glasgow
  • Miguel A. Pineda

William Harnett has published extensively in various scientific venues. The most frequent publication sources are:

  • Parasite Immunology
  • PLoS Pathogens
  • Frontiers in Immunology
  • Frontiers in Tropical Diseases
  • Biochemical Society Transactions

Some of their recent published papers include:

  • "The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing" (2020) in PLoS Pathogens
  • "Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts" (2021) in PLoS Pathogens
  • "Temperate Propolis Has Anti-Inflammatory Effects and Is a Potent Inhibitor of Nitric Oxide Formation in Macrophages" (2020) in Metabolites
  • "Epigenetic changes induced by parasitic worms and their excretory-secretory products" (2024) in Biochemical Society Transactions
  • "The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing" (2022) in Frontiers in Immunology

Best Publications

  • A Filarial Nematode-Secreted Product Signals Dendritic Cells to Acquire a Phenotype That Drives Development of Th2 Cells

    Michael Whelan;Margaret M. Harnett;Katrina M. Houston;Vanshree Patel

  • Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62

    Helen S. Goodridge;Fraser A. Marshall;Kathryn J. Else;Katrina M. Houston

  • IL-33/ST2 signalling and crosstalk with FcεRI and TLR4 is targeted by the parasitic worm product, ES-62

    Dimity H. Ball;Lamyaa Al-Riyami;William Harnett;Margaret M. Harnett

  • Inhibition of FcεRI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

    Alirio J. Melendez;Margaret M. Harnett;Peter N. Pushparaj;Ws Fred Wong

  • A Novel Therapeutic Approach Targeting Articular Inflammation Using the Filarial Nematode-Derived Phosphorylcholine-Containing Glycoprotein ES-62

    Iain B. McInnes;Bernard P. Leung;Margaret Harnett;J. Alastair Gracie

  • Helminth-derived immunomodulators: can understanding the worm produce the pill?

    William Harnett;Margaret M. Harnett

  • Phosphorylcholine: friend or foe of the immune system?

    William Harnett;Margaret M Harnett

  • Secretory products of helminth parasites as immunomodulators.

    William Harnett

  • Increased exposure of parasite antigens at the surface of adult male Schistosoma mansoni exposed to praziquantel in vitro.

    W. Harnett;J. R. Kusel

  • Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses

    Helen S Goodridge;William Harnett;Foo Y Liew;Margaret M Harnett

  • Inhibition of murine B cell proliferation and down-regulation of protein kinase C levels by a phosphorylcholine-containing filarial excretory-secretory product.

    W Harnett;M M Harnett

  • Modulation of Macrophage Cytokine Production by ES-62, a Secreted Product of the Filarial Nematode Acanthocheilonema viteae

    Helen S. Goodridge;Emma H. Wilson;William Harnett;Carol C. Campbell

  • Structural Studies of N-Glycans of Filarial Parasites CONSERVATION OF PHOSPHORYLCHOLINE-SUBSTITUTED GLYCANS AMONG SPECIES AND DISCOVERY OF NOVEL CHITO-OLIGOMERS

    Stuart M. Haslam;Katrina M. Houston;William Harnett;Andrew J. Reason

  • Characterisation of the phosphorylcholine-containing N-linked oligosaccharides in the excretory-secretory 62 kDa glycoprotein of Acanthocheilonema viteae

    Stuart M Haslam;Kay-Hooi Khoo;Katrina M Houston;William Harnett

  • The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis

    M.M. Harnett;Dorothy E. Kean;A. Boitelle;S. McGuiness

  • The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17-producing cellular network at multiple sites.

    Miguel A. Pineda;Mairi A. McGrath;Pauline C. Smith;Lamyaa Al-Riyami

  • Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced Arthritis

    Lamyaa Al-Riyami;Miguel A Pineda;Justyna Rzepecka;Judith K Huggan

  • Immunomodulatory properties of a phosphorylcholine-containing secreted filarial glycoprotein.

    William Harnett;Maureen R. Deehan;Katrina M. Houston;Margaret M. Harnett

  • ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae

    Miguel A. Pineda;Felicity Lumb;Margaret M. Harnett;William Harnett

  • Modulation of the host immune system by phosphorylcholine-containing glycoproteins secreted by parasitic filarial nematodes.

    William Harnett;Margaret M. Harnett

  • Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology

    Malcolm M. Kennedy;William Harnett

Frequent Co-Authors

Margaret M. Harnett
Margaret M. Harnett University of Glasgow
Malcolm W. Kennedy
Malcolm W. Kennedy University of Glasgow
Iain B. McInnes
Iain B. McInnes University of Glasgow
Foo Y. Liew
Foo Y. Liew University of Glasgow
Eileen Devaney
Eileen Devaney University of Glasgow
Stuart M. Haslam
Stuart M. Haslam Imperial College London
Colin Selman
Colin Selman University of Glasgow
Rudolf Geyer
Rudolf Geyer University of Giessen
Bernard P. Leung
Bernard P. Leung Singapore Institute of Technology
Anne Dell
Anne Dell Imperial College London

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