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Immunology

D-Index
57
Citations
13174
World Ranking
3604
National Ranking
310

Overview

Andrew S. MacDonald is affiliated with the University of Manchester in the United Kingdom. Their primary fields of study include Immunology and Microbiology, with a notable focus also on Medicine. The range of subfields they contribute to spans Immunology, Parasitology, Molecular Biology, Biomedical Engineering, and Infectious Diseases.

MacDonald's research addresses a variety of topics, particularly concentrating on Parasites and Host Interactions, Immune cells in cancer, Parasite Biology and Host Interactions, Gut microbiota and health, IL-33, ST2, and ILC Pathways, Immune Cell Function and Interaction, and Research on Leishmaniasis Studies.

Their publication record includes recent papers such as:

  • "The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity," 2022, Mucosal Immunology
  • "The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation," 2021, Nature Communications
  • "Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication," 2020, Science Advances
  • "Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models," 2020, Frontiers in Immunology
  • "T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity," 2023, Immunity

Frequent co-authors of MacDonald include Sheila Brown, Alice Costain, Peter C. Cook, Stefano A. P. Colombo, and Emma L. Houlder. They have collaborated extensively on numerous research outputs.

The scientist often publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Frontiers in Immunology, SSRN Electronic Journal, and the Journal of Hepatology.

Best Publications

  • Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

    Stephen J. Jenkins;Dominik Ruckerl;Peter C. Cook;Lucy H. Jones

  • The immunobiology of schistosomiasis

    Edward J. Pearce;Andrew S. MacDonald

  • CD8− Dendritic Cell Activation Status Plays an Integral Role in Influencing Th2 Response Development

    Andrew S. MacDonald;Amy D. Straw;Beverley Bauman;Edward J. Pearce

  • CD11c depletion severely disrupts Th2 induction and development in vivo

    Alexander T. Phythian-Adams;Peter C. Cook;Rachel J. Lundie;Lucy H. Jones

  • Immunology of Parasitic Helminth Infections

    Andrew S. MacDonald;Maria Ilma Araujo;Edward J. Pearce

  • Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell‐to‐cell contact

    P'ng Loke;Andrew S. MacDonald;Amy Robb;Rick M. Maizels

  • IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.

    V S Pelly;Y Kannan;S M Coomes;L J Entwistle

  • Cutting Edge: Th2 Response Induction by Dendritic Cells: A Role for CD40

    Andrew S MacDonald;Amy D Straw;Nicole M Dalton;Edward J Pearce

  • Cutting Edge: Dendritic Cells Copulsed with Microbial and Helminth Antigens Undergo Modified Maturation, Segregate the Antigens to Distinct Intracellular Compartments, and Concurrently Induce Microbe-Specific Th1 and Helminth-Specific Th2 Responses

    Laura Cervi;Andrew S. MacDonald;Colleen Kane;Florence Dzierszinski

  • Schistosome Egg Migration: Mechanisms, Pathogenesis and Host Immune Responses.

    Alice H. Costain;Alice H. Costain;Andrew S. MacDonald;Hermelijn H. Smits

  • Role of CD4 T Cell Help and Costimulation in CD8 T Cell Responses During Listeria monocytogenes Infection

    Devon J. Shedlock;Jason K. Whitmire;Joyce Tan;Andrew S. MacDonald

  • The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.

    Freya R Svedberg;Freya R Svedberg;Sheila L Brown;Maria Z Krauss;Laura Campbell

  • Alarming dendritic cells for Th2 induction

    Andrew S. MacDonald;Rick M. Maizels

  • Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

    Marie Pariollaud;Julie E. Gibbs;Thomas W. Hopwood;Sheila Brown

  • Parasite-Derived MicroRNAs in Host Serum As Novel Biomarkers of Helminth Infection

    Anna M. Hoy;Rachel J. Lundie;Alasdair C Ivens;Juan F. Quintana

  • RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

    Rachel E Rigby;Lauren M Webb;Karen J Mackenzie;Yue Li

  • Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo.

    Stephen J. Jenkins;Georgia Perona-Wright;Alan G. F. Worsley;Naoto Ishii

  • A Brugia malayi Homolog of Macrophage Migration Inhibitory Factor Reveals an Important Link Between Macrophages and Eosinophil Recruitment During Nematode Infection

    Franco H. Falcone;P’ng Loke;Xingxing Zang;Andrew S. MacDonald

  • Profound suppression of cellular proliferation mediated by the secretions of nematodes

    Judith E. Allen;Andrew S. Macdonald

  • ICOS controls Foxp3+ regulatory T-cell expansion, maintenance and IL-10 production during helminth infection

    Stephen A. Redpath;Nienke van der Werf;Ana M. Cervera;Andrew S. MacDonald

  • Dynamics of Colon Monocyte and Macrophage Activation During Colitis

    Gareth-Rhys Jones;Calum C. Bain;Thomas M. Fenton;Aoife Kelly;Aoife Kelly

  • Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

    Peter C. Cook;Lucy H. Jones;Stephen J. Jenkins;Thomas A. Wynn

Frequent Co-Authors

Judith E. Allen
Judith E. Allen University of Manchester
Rick M. Maizels
Rick M. Maizels University of Glasgow
Edward J. Pearce
Edward J. Pearce Johns Hopkins University
P'ng Loke
P'ng Loke National Institutes of Health
Alasdair Ivens
Alasdair Ivens University of Edinburgh
David A. Gray
David A. Gray University of Nottingham
David J. Thornton
David J. Thornton Wellcome Centre for Cell-Matrix Research
Donald J. Davidson
Donald J. Davidson University of Edinburgh
Stephen M. Anderton
Stephen M. Anderton University of Edinburgh
Adrian Bird
Adrian Bird University of Edinburgh

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