The scientist’s investigation covers issues in Immunology, Cell biology, Interleukin 4, Immune system and Schistosoma mansoni. Borrowing concepts from Brugia malayi, Andrew S. MacDonald weaves in ideas under Immunology. His research integrates issues of Cell, Dendritic cell, Antigen, Th2 response and CD40 in his study of Cell biology.
His Interleukin 4 research is multidisciplinary, relying on both Inflammation and Antigen-presenting cell. While the research belongs to areas of Immune system, Andrew S. MacDonald spends his time largely on the problem of Cellular differentiation, intersecting his research to questions surrounding Endogeny, Pathogenic organism and Carboxyfluorescein diacetate succinimidyl ester. His Schistosoma mansoni research is multidisciplinary, incorporating elements of Fold change, RNA extraction, DNA microarray, microRNA and Disease.
Immunology, Cell biology, Immune system, Schistosoma mansoni and Dendritic cell are his primary areas of study. All of his Immunology and Antigen, T cell, Interleukin 4, Inflammation and Heligmosomoides polygyrus investigations are sub-components of the entire Immunology study. His study in Cell biology is interdisciplinary in nature, drawing from both Cellular differentiation, CD40, Th2 response, Antigen-presenting cell and In vivo.
Andrew S. MacDonald has included themes like Helminths, Downregulation and upregulation, Disease and Effector in his Immune system study. His studies deal with areas such as FOXP3, Pathogenesis and Interleukin 10 as well as Schistosoma mansoni. His Dendritic cell study combines topics from a wide range of disciplines, such as Adoptive cell transfer and MHC class II.
His main research concerns Cell biology, Immune system, Immunology, Inflammation and Schistosoma mansoni. The Cell biology study combines topics in areas such as Cell growth, Dendritic cell, Antigen, Chemokine and Circadian rhythm. His Antigen research includes themes of Cell, In vitro, Cellular differentiation, In vivo and Heligmosomoides polygyrus.
Andrew S. MacDonald mostly deals with Immunity in his studies of Immunology. His Inflammation study integrates concerns from other disciplines, such as DNA methylation, Aryl hydrocarbon receptor, Neutrophilia, Monocyte and Cathelicidin. His work carried out in the field of Schistosoma mansoni brings together such families of science as Gut flora, Microbiology, Pathogenesis and Regulatory B cells.
His primary areas of study are Cell biology, Inflammation, Trichuris muris, Helminths and Circadian rhythm. His work deals with themes such as Microbiome, Gastrointestinal Microbiome, Carnitine and Central nervous system, which intersect with Cell biology. His Inflammation study is concerned with the larger field of Immunology.
In the subject of general Immunology, his work in Tumor necrosis factor alpha, CD14 and Monocyte is often linked to CCL8 and CCL7, thereby combining diverse domains of study. Andrew S. MacDonald has researched Helminths in several fields, including Cancer development, Immune system, Granuloma formation and Hepatic tissue. Andrew S. MacDonald combines subjects such as Proinflammatory cytokine, Innate immune system and Endogeny with his study of Circadian rhythm.
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Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation
Stephen J. Jenkins;Dominik Ruckerl;Peter C. Cook;Lucy H. Jones.
Science (2011)
The immunobiology of schistosomiasis
Edward J. Pearce;Andrew S. MacDonald.
Nature Reviews Immunology (2002)
Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI.
Geoffrey James Parker;Caleb Roberts;Andrew Macdonald;Giovanni A Buonaccorsi.
Magnetic Resonance in Medicine (2006)
The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis.
AA MacDonald;GP Herbison;Marian Showell;Cynthia Farquhar.
Human Reproduction Update (2010)
CD8− Dendritic Cell Activation Status Plays an Integral Role in Influencing Th2 Response Development
Andrew S. MacDonald;Amy D. Straw;Beverley Bauman;Edward J. Pearce.
Journal of Immunology (2001)
CD11c depletion severely disrupts Th2 induction and development in vivo
Alexander T. Phythian-Adams;Peter C. Cook;Rachel J. Lundie;Lucy H. Jones.
Journal of Experimental Medicine (2010)
Immunology of Parasitic Helminth Infections
Andrew S. MacDonald;Maria Ilma Araujo;Edward J. Pearce.
Infection and Immunity (2002)
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell‐to‐cell contact
P'ng Loke;Andrew S. MacDonald;Amy Robb;Rick M. Maizels.
European Journal of Immunology (2000)
Cutting Edge: Dendritic Cells Copulsed with Microbial and Helminth Antigens Undergo Modified Maturation, Segregate the Antigens to Distinct Intracellular Compartments, and Concurrently Induce Microbe-Specific Th1 and Helminth-Specific Th2 Responses
Laura Cervi;Andrew S. MacDonald;Colleen Kane;Florence Dzierszinski.
Journal of Immunology (2004)
Cutting Edge: Th2 Response Induction by Dendritic Cells: A Role for CD40
Andrew S MacDonald;Amy D Straw;Nicole M Dalton;Edward J Pearce.
Journal of Immunology (2002)
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