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Miguel J. Stadecker

Miguel J. Stadecker

D-Index & Metrics

Immunology

D-Index
53
Citations
8528
World Ranking
4005
National Ranking
1826

Overview

Miguel J. Stadecker is affiliated with Tufts University in the United States and conducts research primarily within the fields of Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine. Their work focuses extensively on parasitology, molecular biology, and immunology, with additional contributions in hematology and hepatology.

The main research topics addressed by Stadecker include:

  • Parasites and Host Interactions
  • Inflammasome and Immune Disorders
  • Interferon and Immune Responses
  • Autoimmune and Inflammatory Disorders Research
  • Hepatitis Viruses Studies and Epidemiology
  • Amoebic Infections and Treatments
  • Parasite Biology and Host Interactions

Stadecker's recent scientific papers include:

  • The balance between gasdermin D and STING signaling shapes the severity of schistosome immunopathology, 2023, published in Proceedings of the National Academy of Sciences
  • NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni, 2025, published in PLoS Pathogens
  • NLRP3 and AIM2 inflammasome-triggered Th17 cell response promotes severe immunopathology in schistosomiasis, 2021, published in The Journal of Immunology
  • NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni, 2024, published in bioRxiv (Cold Spring Harbor Laboratory)
  • Effective Control of Schistosoma haematobium Infection in a Ghanaian Community following Installation of a Water Recreation Area, 2020, published in UNC Libraries

Frequent co-authors collaborating with Stadecker include:

  • Parisa Kalantari
  • Ilana Shecter
  • Yoelkys Morales
  • Emily Miller
  • Jacob Hopkins

Stadecker's research is regularly published in venues such as:

  • The Journal of Immunology
  • Proceedings of the National Academy of Sciences
  • PLoS Pathogens
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries

Their investigations primarily explore the immunopathology associated with parasitic infections, especially schistosomiasis, with particular attention to inflammasome signaling pathways and host immune responses. The integration of molecular biology techniques and immunological analyses characterizes the methodological approach throughout the body of their work.

Best Publications

  • Protective immune mechanisms in helminth infection

    Robert M. Anthony;Laura I. Rutitzky;Joseph F. Urban;Miguel J. Stadecker

  • The immune response to parasitic helminths: insights from murine models.

    William C. Gause;Joseph F. Urban;Miguel J. Stadecker

  • Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases.

    Hans Reiser;Miguel J. Stadecker

  • Severe CD4 T Cell-Mediated Immunopathology in Murine Schistosomiasis Is Dependent on IL-12p40 and Correlates with High Levels of IL-17

    Laura I. Rutitzky;Jessica R. Lopes da Rosa;Miguel J. Stadecker

  • Proteomic Analysis of Schistosoma mansoni Egg Secretions

    Cynthia L. Cass;Jeffrey R. Johnson;Lindsay L. Califf;Tao Xu

  • Lichen planus–like eruptions: An emerging side effect of tumor necrosis factor-α antagonists

    Adam Asarch;Alice B. Gottlieb;Jin Lee;Katherine S. Masterpol

  • Synthesis and release of thymidine by macrophages.

    Miguel J. Stadecker;Jesus Calderon;Manfred L. Karnovsky;Emil R. Unanue

  • The immunobiology of Th1 polarization in high-pathology schistosomiasis.

    Miguel J. Stadecker;Hiroko Asahi;Eduardo Finger;Hector J. Hernandez

  • Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis.

    P. O. Flores-Villanueva;Xin Xiao Zheng;T. B. Strom;M. J. Stadecker

  • The Cutaneous Basophil Response to Phytohemagglutinin in Chickens

    Miguel J. Stadecker;Miodrag Lukic;Ann Dvorak;Sidney Leskowitz

  • Colonization with Heligmosomoides polygyrus Suppresses Mucosal IL-17 Production

    David E. Elliott;David E. Elliott;Ahmed Metwali;Ahmed Metwali;John Leung;John Leung;Tommy Setiawan

  • In infection with Schistosoma mansoni, B cells are required for T helper type 2 cell responses but not for granuloma formation.

    H J Hernandez;Y Wang;M J Stadecker

  • Propranolol ameliorates the development of portal-systemic shunting in a chronic murine schistosomiasis model of portal hypertension.

    S K Sarin;R J Groszmann;P G Mosca;M Rojkind

  • IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17.

    Laura I. Rutitzky;Lindsey Bazzone;Mara G. Shainheit;Barbara Joyce-Shaikh

  • IL-10 is crucial for the transition from acute to chronic disease state during infection of mice with Schistosoma mansoni.

    Clare H. Sadler;Laura I. Rutitzky;Miguel J. Stadecker;R. Alan Wilson

  • Expression of class II, but not class I, major histocompatibility complex molecules is required for granuloma formation in infection with Schistosoma mansoni

    Hector J. Hernandez;Yong Wang;Nia Tzellas;Miguel J. Stadecker

  • Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection

    Laura I. Rutitzky;Hector J. Hernandez;Miguel J. Stadecker

  • Memory T lymphocyte hyporesponsiveness to non-cognate stimuli: a key factor in age-related immunodeficiency.

    Kevin Flurkey;Miguel Stadecker;Richard A. Miller

  • Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. Effect on expression of B7 and B7-2 costimulatory molecules by macrophages.

    P O Flores Villanueva;H Reiser;M J Stadecker

  • Rosette Formation by Guinea Pig Thymocytes and Thymus Derived Lymphocytes with Rabbit Red Blood Cells

    Miguel J. Stadecker;Gene Bishop;Henry H. Wortis

Frequent Co-Authors

Donald A. Harn
Donald A. Harn University of Georgia
Joseph F. Urban
Joseph F. Urban United States Department of Agriculture
Clemens Sorg
Clemens Sorg University of Münster
Emil R. Unanue
Emil R. Unanue Washington University in St. Louis
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Sergij Goerdt
Sergij Goerdt Heidelberg University
Ernst Peterhans
Ernst Peterhans University of Bern
P'ng Loke
P'ng Loke National Institutes of Health
Thomas W. Jungi
Thomas W. Jungi University of Bern
Michael S. McGrath
Michael S. McGrath University of California, San Francisco

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