Pekka Lappalainen

Research.com Recognitions

• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• Filopodia: molecular architecture and cellular functions

  Pieta K. Mattila;Pekka Lappalainen

  2080
  Citations

• Stress fibers are generated by two distinct actin assembly mechanisms in motile cells

  Pirta Hotulainen;Pekka Lappalainen

  1134
  Citations

• Actin stress fibers--assembly, dynamics and biological roles.

  Sari Tojkander;Gergana Gateva;Pekka Lappalainen

  1019
  Citations

• Cofilin promotes rapid actin filament turnover in vivo

  Pekka Lappalainen;David G. Drubin

  591
  Citations

• Regulation of the Actin Cytoskeleton-Plasma Membrane Interplay by Phosphoinositides

  Juha Saarikangas;Hongxia Zhao;Pekka Lappalainen

  568
  Citations

• Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain–like mechanism

  Pieta K. Mattila;Anette Pykäläinen;Juha Saarikangas;Ville O. Paavilainen

  468
  Citations

• Actin-depolymerizing Factor and Cofilin-1 Play Overlapping Roles in Promoting Rapid F-Actin Depolymerization in Mammalian Nonmuscle Cells

  Pirta Hotulainen;Eija Paunola;Maria K. Vartiainen;Pekka Lappalainen

  466
  Citations

• Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

  Pirta Hotulainen;Olaya Llano;Sergei Smirnov;Kimmo Tanhuanpää

  417
  Citations

• Molecular mechanisms of membrane deformation by I-BAR domain proteins.

  Juha Saarikangas;Hongxia Zhao;Anette Pykäläinen;Pasi Laurinmäki

  364
  Citations

• Regulation of cytoskeletal dynamics by actin-monomer-binding proteins

  Ville O Paavilainen;Enni Bertling;Sandra Falck;Pekka Lappalainen

  333
  Citations

• Mechanisms of actin stress fibre assembly.

  P. Naumanen;P. Lappalainen;P. Hotulainen

  323
  Citations

• A molecular pathway for myosin II recruitment to stress fibers.

  Sari Tojkander;Gergana Gateva;Galina Schevzov;Pirta Hotulainen

  307
  Citations

• IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

  Giorgio Scita;Stefano Confalonieri;Pekka Lappalainen;Shiro Suetsugu

  306
  Citations

• Leiomodin Is an Actin Filament Nucleator in Muscle Cells

  David Chereau;Malgorzata Boczkowska;Aneta Skwarek-Maruszewska;Ikuko Fujiwara

  303
  Citations

• Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis

  Pekka Lappalainen;Elena V. Fedorov;Alexander A. Fedorov;Steven C. Almo

  296
  Citations

• Cyclase-associated Protein 1 (CAP1) Promotes Cofilin-induced Actin Dynamics in Mammalian Nonmuscle Cells

  Enni Bertling;Pirta Hotulainen;Pieta K. Mattila;Tanja Matilainen

  290
  Citations

• The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics

  Maria K. Vartiainen;Tuija Mustonen;Pieta K. Mattila;Pauli J. Ojala

  288
  Citations

• WH2 domain: a small, versatile adapter for actin monomers.

  Eija Paunola;Pieta K. Mattila;Pekka Lappalainen

  284
  Citations

• Tropomyosin – master regulator of actin filament function in the cytoskeleton

  Peter W. Gunning;Edna C. Hardeman;Pekka Lappalainen;Daniel P. Mulvihill

  283
  Citations

• The ADF Homology (ADF-H) Domain: A Highly Exploited Actin-binding Module

  Pekka Lappalainen;Michael M. Kessels;M. Jamie T.V. Cope;David G. Drubin

  268
  Citations