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Biology and Biochemistry

D-Index
57
Citations
11205
World Ranking
13883
National Ranking
5869

Overview

David R. Kovar is a researcher affiliated with the University of Chicago in the United States. Their primary field of study is Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Cell Biology, Molecular Biology, Cardiology and Cardiovascular Medicine, Biophysics, and Atomic and Molecular Physics, and Optics.

Their research covers several main topics, including:

  • Cellular Mechanics and Interactions
  • Cardiomyopathy and Myosin Studies
  • Advanced Fluorescence Microscopy Techniques
  • Microtubule and mitosis dynamics
  • Force Microscopy Techniques and Applications
  • Fungal and yeast genetics research
  • Heat shock proteins research

Several frequent co-authors have collaborated with David R. Kovar, among them:

  • Cristian Suarez (14 joint publications)
  • Margaret L. Gardel (8 joint publications)
  • Jonathan D. Winkelman (6 joint publications)
  • Caitlin A. Anderson (6 joint publications)
  • Rachel S. Kadzik (5 joint publications)

David R. Kovar has published multiple papers across key venues. Among the most frequent publication venues are:

  • Biophysical Journal (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • UNC Libraries (4 publications)
  • Cytoskeleton (3 publications)
  • Journal of Cell Science (2 publications)

Selected recent papers authored or co-authored by David R. Kovar include:

  • "F-Actin Cytoskeleton Network Self-Organization Through Competition and Cooperation," 2020, Annual Review of Cell and Developmental Biology
  • "Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism," 2020, Proceedings of the National Academy of Sciences
  • "LIM domain proteins in cell mechanobiology," 2021, Cytoskeleton
  • "Mechanism of actin filament nucleation," 2021, Biophysical Journal
  • "Cracked actin filaments as mechanosensitive receptors," 2024, Biophysical Journal

Best Publications

  • Control of the assembly of ATP- and ADP-actin by formins and profilin.

    David R. Kovar;Elizabeth S. Harris;Rachel Mahaffy;Henry N. Higgs

  • Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces.

    David R. Kovar;Thomas D. Pollard

  • Latrunculin B Has Different Effects on Pollen Germination and Tube Growth

    Bryan C. Gibbon;David R. Kovar;Christopher J. Staiger

  • Spatial and Temporal Pathway for Assembly and Constriction of the Contractile Ring in Fission Yeast Cytokinesis

    Jian-Qiu Wu;Jeffrey R. Kuhn;David R. Kovar;Thomas D. Pollard

  • The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin.

    David R. Kovar;Jeffrey R. Kuhn;Andrea L. Tichy;Thomas D. Pollard

  • Identification and Characterization of a Small Molecule Inhibitor of Formin-Mediated Actin Assembly

    Syed A. Rizvi;Erin M. Neidt;Jiayue Cui;Zach Feiger

  • Molecular details of formin-mediated actin assembly

    David R Kovar

  • Assembly of the cytokinetic contractile ring from a broad band of nodes in fission yeast

    Jian-Qiu Wu;Vladimir Sirotkin;David R. Kovar;Matthew Lord

  • Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

    Jeremy D. Rotty;Congying Wu;Elizabeth M. Haynes;Cristian Suarez

  • Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

    Cristian Suarez;Robert T. Carroll;Thomas A. Burke;Jenna R. Christensen

  • Model of Formin-Associated Actin Filament Elongation

    Dimitrios Vavylonis;Dimitrios Vavylonis;David R. Kovar;Ben O'Shaughnessy;Thomas D. Pollard

  • Profilin and actin-depolymerizing factor: modulators of actin organization in plants

    Christopher J. Staiger;Bryan C. Gibbon;David R. Kovar;Laura E. Zonia

  • Homeostatic Actin Cytoskeleton Networks Are Regulated by Assembly Factor Competition for Monomers

    Thomas A. Burke;Jenna R. Christensen;Elisabeth Barone;Cristian Suarez

  • Signal-Mediated Depolymerization of Actin in Pollen during the Self-Incompatibility Response

    Benjamin N. Snowman;David R. Kovar;Galina Shevchenko;Vernonica E. Franklin-Tong

  • Maize Profilin Isoforms Are Functionally Distinct

    David R. Kovar;Bjørn K. Drøbak;Christopher J. Staiger

  • Cytoskeletal dynamics: a view from the membrane.

    Magdalena Bezanilla;Amy S. Gladfelter;David R. Kovar;Wei-Lih Lee

  • Rickettsia Sca2 is a bacterial formin-like mediator of actin-based motility

    Cat M. Haglund;Julie E. Choe;Colleen T. Skau;David R. Kovar

  • A plant-specific kinesin binds to actin microfilaments and interacts with cortical microtubules in cotton fibers.

    Mary L. Preuss;David R. Kovar;Y.-R. Julie Lee;Christopher J. Staiger

  • AtFim1 is an actin filament crosslinking protein from Arabidopsis thaliana.

    David R. Kovar;Christopher J. Staiger;Eric A. Weaver;David W. McCurdy

  • Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin

    Jonathan D. Winkelman;Colleen G. Bilancia;Mark Peifer;David R. Kovar

Frequent Co-Authors

Christopher J. Staiger
Christopher J. Staiger Purdue University West Lafayette
Gregory A. Voth
Gregory A. Voth University of Chicago
Thomas D. Pollard
Thomas D. Pollard Yale University
Jake Baum
Jake Baum University of New South Wales
Matthew Tirrell
Matthew Tirrell University of Chicago
Roberto Dominguez
Roberto Dominguez University of Pennsylvania
Mark Peifer
Mark Peifer University of North Carolina at Chapel Hill
Laurent Blanchoin
Laurent Blanchoin Grenoble Alpes University
Fred C. MacKintosh
Fred C. MacKintosh Rice University
Eric Hanssen
Eric Hanssen University of Melbourne

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