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Thomas D. Pollard

Thomas D. Pollard

D-Index & Metrics

Biology and Biochemistry

D-Index
144
Citations
82985
World Ranking
227
National Ranking
157

Overview

Thomas D. Pollard is affiliated with Yale University in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions in fields such as cell biology, molecular biology, biophysics, cardiology and cardiovascular medicine, and structural biology.

The scientist's work covers a range of main topics, including:

  • Cellular Mechanics and Interactions
  • Cardiomyopathy and Myosin Studies
  • Advanced Fluorescence Microscopy Techniques
  • Fungal and yeast genetics research
  • Microtubule and mitosis dynamics
  • Advanced Electron Microscopy Techniques and Applications
  • Genetic Neurodegenerative Diseases

Recent publications by Thomas D. Pollard demonstrate ongoing research in actin filament dynamics, cell division, and cytoskeletal structure. Notable papers include:

  • "Force and phosphate release from Arp2/3 complex promote dissociation of actin filament branches," 2020, Proceedings of the National Academy of Sciences
  • "Structural basis for polarized elongation of actin filaments," 2020, Proceedings of the National Academy of Sciences
  • "Mechanism of actin filament branch formation by Arp2/3 complex revealed by a high-resolution cryo-EM structure of the branch junction," 2022, Proceedings of the National Academy of Sciences
  • "The number of cytokinesis nodes in mitotic fission yeast scales with cell size," 2022, eLife
  • "Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis," 2021, Molecular Biology of the Cell

Frequent collaboration is a characteristic of their work, with common co-authors including:

  • Steven Z. Chou
  • Gregory A. Voth
  • Vilmos Zsolnay
  • Wenxiang Cao
  • Enrique M. De La Cruz

Thomas D. Pollard's publications are often found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Molecular Biology of the Cell
  • Nature Communications

Best Publications

  • Cellular Motility Driven by Assembly and Disassembly of Actin Filaments

    Thomas D Pollard;Gary G Borisy

  • Actin, a Central Player in Cell Shape and Movement

    Thomas D. Pollard;John A. Cooper

  • Actin and Actin-Binding Proteins. A Critical Evaluation of Mechanisms and Functions

    Thomas D. Pollard;John A. Cooper

  • Molecular Mechanisms Controlling Actin Filament Dynamics in Nonmuscle Cells

    T D Pollard;L Blanchoin;R D Mullins

  • The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments

    R. Dyche Mullins;John A. Heuser;Thomas D. Pollard

  • Actin and myosin and cell movement.

    Pollard Td;Weihing Rr

  • Regulation of Actin Filament Assembly by Arp2/3 Complex and Formins

    Thomas D Pollard

  • Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments.

    Thomas D. Pollard

  • Mechanism of action of cytochalasin B on actin

    Susan MacLean-Fletcher;Thomas D. Pollard

  • Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex.

    Machesky Lm;Mullins Rd;Higgs Hn;Kaiser Da

  • Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

    Henry N. Higgs;Thomas D. Pollard

  • Mechanism of Actin Filament Turnover by Severing and Nucleation at Different Concentrations of ADF/Cofilin.

    Ernesto Andrianantoandro;Thomas D. Pollard

  • Actin and Actin-Binding Proteins

    Thomas D. Pollard

  • Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

    Laurent Blanchoin;Kurt J. Amann;Henry N. Higgs;Jean-Baptiste Marchand

  • Fluorescent antibody localization of myosin in the cytoplasm, cleavage furrow, and mitotic spindle of human cells.

    Keigi Fujiwara;Thomas D. Pollard

  • Crystal Structure of Arp2/3 Complex

    Robert C. Robinson;Kirsi Turbedsky;Donald A. Kaiser;Jean-Baptiste Marchand

  • Activation by Cdc42 and Pip2 of Wiskott-Aldrich Syndrome Protein (Wasp) Stimulates Actin Nucleation by Arp2/3 Complex

    Henry N. Higgs;Thomas D. Pollard

  • Purification of a Cortical Complex Containing Two Unconventional Actins from Acanthamoeba by Affinity Chromatography on Profilin-Agarose

    Laura M Machesky;Simon J Atkinson;Christophe Ampe;Joel Vandekerckhove

  • Control of the assembly of ATP- and ADP-actin by formins and profilin.

    David R. Kovar;Elizabeth S. Harris;Rachel Mahaffy;Henry N. Higgs

  • Acanthamoeba Myosin I. ISOLATION FROM ACANTHAMOEBA CASTELLANII OF AN ENZYME SIMILAR TO MUSCLE MYOSIN

    Thomas D. Pollard;Edward D. Korn

Frequent Co-Authors

John A. Cooper
John A. Cooper Washington University in St. Louis
Laurent Blanchoin
Laurent Blanchoin Grenoble Alpes University
Laura M. Machesky
Laura M. Machesky University of Glasgow
Henry N. Higgs
Henry N. Higgs Dartmouth College
David R. Kovar
David R. Kovar University of Chicago
Gregory A. Voth
Gregory A. Voth University of Chicago
Daniel P. Kiehart
Daniel P. Kiehart Duke University
Edward D. Korn
Edward D. Korn National Institutes of Health
Rong Li
Rong Li Johns Hopkins University School of Medicine
David L. Rimm
David L. Rimm Yale University

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