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D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
26009
World Ranking
3148
National Ranking
1591

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Mark Peifer is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research mainly revolves around biochemistry, genetics, and molecular biology, with a particular focus on cell biology and molecular biology. Additional subfields include cellular and molecular neuroscience, biomaterials, and public health, environmental, and occupational health.

The scientist's body of work covers several main topics, that include:

  • Cellular mechanics and interactions
  • Hippo pathway signaling and YAP/TAZ
  • Wnt/β-catenin signaling in development and cancer
  • Microtubule and mitosis dynamics
  • Cellular transport and secretion
  • Cancer-related gene regulation
  • Silk-based biomaterials and applications

Mark Peifer has contributed to a range of publications, notably in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Molecular Biology of the Cell, The Journal of Cell Biology, and Journal of Cell Science. The distribution includes multiple papers in each, with UNC Libraries hosting the largest number of contributions.

Frequent coauthors collaborating with Mark Peifer include:

  • Noah J. Gurley
  • Kevin C. Slep
  • Mira I. Pronobis
  • T. Amber Butcher
  • Joanna Poulton

Selected recent papers authored or coauthored by Mark Peifer include:

  • "Orchestrating morphogenesis: building the body plan by cell shape changes and movements" (2020), published in Development
  • "Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis" (2021), published in The Journal of Cell Biology
  • "Micron-scale supramolecular myosin arrays help mediate cytoskeletal assembly at mature adherens junctions" (2021), published in The Journal of Cell Biology
  • "Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex" (2020), published in Molecular Biology of the Cell
  • "Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms" (2022), published in Molecular Biology of the Cell

In 2009, Mark Peifer was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

    Mark Peifer;Paul Polakis

  • Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF

    Marc van de Wetering;Robert Cavallo;Dennis Dooijes;Moniek van Beest

  • Drosophila Tcf and Groucho interact to repress Wingless signalling activity

    Robert A. Cavallo;Rachel T. Cox;Melissa M. Moline;Jeroen Roose

  • A repeating amino acid motif shared by proteins with diverse cellular roles

    Mark Peifer;Sven Berg;Albert B. Reynolds

  • Molecular Genetics of the Bithorax Complex in Drosophila melanogaster

    Welcome Bender;Michael Akam;François Karch;Philip A. Beachy

  • Cadherins in embryonic and neural morphogenesis

    Ulrich Tepass;Kevin Truong;Dorothea Godt;Mitsuhiko Ikura

  • The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin

    Mark Peifer;Eric Francis Wieschaus

  • wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo

    Mark Peifer;Dari Sweeton;Michael Casey;Eric Wieschaus

  • The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties.

    Mark Peifer;Pierre D. McCrea;Kathleen J. Green;Eric Wieschaus

  • β-Catenin as Oncogene--The Smoking Gun

    Mark Peifer

  • An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling.

    Sandra Orsulic;Mark Peifer

  • The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila.

    Tony J.C. Harris;Mark Peifer

  • The abdominal region of the bithorax complex

    François Karch;Barbara Weiffenbach;Mark Peifer;Welcome Bender

  • Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis.

    Rachel T. Cox;Catherine Kirkpatrick;Mark A Peifer

  • Wnt Signaling from Development to Disease: Insights from Model Systems

    Ken M. Cadigan;Mark A Peifer

  • Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens

    Liang Gao;Lin Shao;Christopher D. Higgins;John S. Poulton

  • extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.

    Cordella Rauskolb;Mark Peifer;Eric Wieschaus

  • The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction

    Jessica K. Sawyer;Nathan J. Harris;Kevin C. Slep;Ulrike Gaul

  • Negative regulation of Armadillo, a Wingless effector in Drosophila

    Li Mei Pai;Sandra Orsulic;Amy Bejsovec;Mark Peifer

  • Phosphorylation of the Drosophila Adherens Junction Protein Armadillo: Roles for Wingless Signal and Zeste-white 3 Kinase

    Mark Peifer;Li Mei Pai;Michael Casey

Frequent Co-Authors

Eric Wieschaus
Eric Wieschaus Princeton University
Sandra Orsulic
Sandra Orsulic University of California, Los Angeles
Welcome Bender
Welcome Bender Harvard University
John R. Pringle
John R. Pringle Stanford University
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Bob Goldstein
Bob Goldstein University of North Carolina at Chapel Hill
Amy S. Gladfelter
Amy S. Gladfelter Duke University
François Karch
François Karch University of Geneva
Joachim Messing
Joachim Messing Rutgers, The State University of New Jersey
Feng Yan
Feng Yan Hong Kong Polytechnic University

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