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Genetics

D-Index
49
Citations
11004
World Ranking
3986
National Ranking
63

Overview

François Karch is a researcher affiliated with the University of Geneva in Switzerland. Their work is situated primarily within the field of Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields including Molecular Biology, Cancer Research, Immunology, Cellular and Molecular Neuroscience, and Ecology, Evolution, Behavior and Systematics.

Their published research addresses a range of topics related to RNA mechanisms, molecular genetics, and invertebrate biology. Main topics covered in their body of work include:

  • RNA Research and Splicing
  • Cancer-related molecular mechanisms research
  • Genomics and Chromatin Dynamics
  • Invertebrate Immune Response Mechanisms
  • Neurobiology and Insect Physiology Research
  • Animal Behavior and Reproduction
  • RNA and protein synthesis mechanisms

Karch has contributed articles to several scientific journals, with frequent publications appearing in venues such as:

  • PLoS Genetics
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)

Representative recent papers authored or co-authored by Karch include:

  • Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success, 2021, Proceedings of the National Academy of Sciences
  • Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference, 2021, PLoS Genetics
  • Upstream open reading frames repress the translation from the iab-8 RNA, 2024, PLoS Genetics
  • Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Karch has collaborated extensively with several researchers, including Robert K. Maeda, Maxime Revel, Yohan Frei, Javier J. Castro Alvarez, and Fabienne Cléard. Their collaborations span multiple publications, reflecting a network of co-authors involved in related fields of study.

Best Publications

  • An optimized transgenesis system for Drosophila using germ-line-specific φC31 integrases

    Johannes Bischof;Robert K. Maeda;Monika Hediger;François Karch

  • Molecular Genetics of the Bithorax Complex in Drosophila melanogaster

    Welcome Bender;Michael Akam;François Karch;Philip A. Beachy

  • The Trithorax-like gene encodes the Drosophila GAGA factor

    Gabriella Farkas;Janos Gausz;Mireille Galloni;Mireille Galloni;Günter Reuter

  • The abdominal region of the bithorax complex

    François Karch;Barbara Weiffenbach;Mark Peifer;Welcome Bender

  • Acetylcholinesterase. Two types of modifications confer resistance to insecticide.

    D Fournier;J.M. Bride;F Hoffmann;F Karch

  • GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

    Jan A. van der Knaap;B.R. Prashanth Kumar;Yuri M. Moshkin;Karin Langenberg

  • abdA expression in Drosophila embryos.

    F Karch;W Bender;B Weiffenbach

  • A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

    H. Gyurkovics;J. Gausz;J. Kummer;F. Karch

  • The ABC of the BX-C: the bithorax complex explained

    Robert K. Maeda;François Karch

  • The plasmid cloning vector pBR325 contains a 482 base-pair-long inverted duplication.

    Pierre Prentki;François Karch;Shigeru Iida;Jürg Meyer

  • Homeo box genes of the Antennapedia and bithorax complexes of Drosophila.

    Michael Regulski;Katherine Harding;Richard Kostriken;Francois Karch

  • The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain.

    Stéphane Barges;Jozsef Mihaly;Mireille Galloni;Mireille Galloni;Kirsten Hagstrom;Kirsten Hagstrom

  • In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element

    Jozsef Mihaly;Ilham Hogga;Janos Gausz;Henrik Gyurkovics

  • The bithorax complex: control of segmental identity.

    Mark Peifer;François Karch;François Karch;Welcome Bender

  • Mcp and Fab-7: molecular analysis of putative boundaries of cis-regulatory domains in the bithorax complex of Drosophila melanogaster

    François Karch;Mireille Galloni;Làszlò Sipos;Janos Gausz

  • The GAGA factor is required in the early Drosophila embryo not only for transcriptional regulation but also for nuclear division

    Krishna Moorthi Bhat;Gabriella Farkas;Francois Karch;Henrik Gyurkovics

  • The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity.

    Rakesh K. Mishra;Jozsef Mihaly;Stéphane Barges;Annick Spierer

  • Histone Chaperones ASF1 and NAP1 Differentially Modulate Removal of Active Histone Marks by LID-RPD3 Complexes during NOTCH Silencing

    Yuri M. Moshkin;Tsung Wai Kan;Henry Goodfellow;Karel Bezstarosti

  • Extensive regions of homology in front of the two hsp70 heat shock variant genes in Drosophila melanogaster.

    François Karch;Istvan Török;Alfred Tissières

  • The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex.

    Mireille Galloni;Henrik Gyurkovics;Paul Schedl;François Karch

Frequent Co-Authors

Paul Schedl
Paul Schedl Princeton University
Welcome Bender
Welcome Bender Harvard University
Mariana F. Wolfner
Mariana F. Wolfner Cornell University
Mark Peifer
Mark Peifer University of North Carolina at Chapel Hill
Didier Fournier
Didier Fournier Centre national de la recherche scientifique, CNRS
Suzanne Eaton
Suzanne Eaton Max Planck Society
Pavel Georgiev
Pavel Georgiev Russian Academy of Sciences
Sarah J. Bray
Sarah J. Bray University of Cambridge

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