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Genetics

D-Index
78
Citations
23394
World Ranking
1695
National Ranking
779

Overview

Richard S. Mann is affiliated with Columbia University in the United States and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields including Molecular Biology, Cellular and Molecular Neuroscience, Plant Science, Genetics, and Cell Biology.

Their work focuses on several main topics:

  • Neurobiology and Insect Physiology Research
  • Genomics and Chromatin Dynamics
  • Developmental Biology and Gene Regulation
  • RNA Research and Splicing
  • CRISPR and Genetic Engineering
  • Chromosomal and Genetic Variations
  • RNA and protein synthesis mechanisms

Richard S. Mann has published numerous papers, with some recent notable titles including:

  • Prediction of protein-ligand binding affinity from sequencing data with interpretable machine learning (2022, Nature Biotechnology)
  • A Systematic Nomenclature for the Drosophila Ventral Nerve Cord (2020, Neuron)
  • Dense and pleiotropic regulatory information in a developmental enhancer (2020, Nature)
  • A size principle for recruitment of Drosophila leg motor neurons (2020, eLife)
  • Cell-type-specific Hox regulatory strategies orchestrate tissue identity (2021, Current Biology)

Frequent coauthors in their research include Siqian Feng, Ryan Loker, Harmen J. Bussemaker, Davys H. Lopez, and Kevin D. Rostam. These collaborations have appeared across various studies contributing significantly to the development of their research themes.

Richard S. Mann has been published primarily in venues such as bioRxiv (Cold Spring Harbor Laboratory), Current Biology, Proceedings of the National Academy of Sciences, SSRN Electronic Journal, and Nature Biotechnology. The majority of their publications are found in bioRxiv, reflecting a strong engagement with preprint dissemination.

Best Publications

  • Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

    Richard Mann;Richard C. Mulligan;David Baltimore

  • The role of DNA shape in protein–DNA recognition

    Remo Rohs;Sean M. West;Alona Sosinsky;Alona Sosinsky;Peng Liu

  • Origins of Specificity in Protein-DNA Recognition

    Remo Rohs;Xiangshu Jin;Sean M. West;Rohit Joshi

  • Improved reference genome of Aedes aegypti informs arbovirus vector control

    Benjamin J. Matthews;Benjamin J. Matthews;Olga Dudchenko;Olga Dudchenko;Sarah B. Kingan;Sergey Koren

  • Swept confocally-aligned planar excitation (SCAPE) microscopy for high speed volumetric imaging of behaving organisms.

    Matthew B. Bouchard;Venkatakaushik Voleti;César S. Mendes;Clay Lacefield

  • Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

    Helke Pöpperl;Mariann Bienz;Michèle Studer;Siu-Kwong Chan

  • Cofactor Binding Evokes Latent Differences in DNA Binding Specificity between Hox Proteins

    Matthew G Slattery;Todd Riley;Peng Liu;Peng Liu;Namiko Abe

  • Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins.

    Richard S. Mann;Siu-Kwong Chan

  • Nuclear Translocation of Extradenticle Requires homothorax, which Encodes an Extradenticle-Related Homeodomain Protein

    Gabrielle E Rieckhof;Fernando Casares;Hyung Don Ryoo;Muna Abu-Shaar

  • The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

    Siu-Kwong Chan;Leah Jaffe;Maria Capovilla;Juan Botas

  • Hox proteins meet more partners

    Richard S Mann;Markus Affolter

  • Structure of a DNA-bound Ultrabithorax–Extradenticle homeodomain complex

    Jonathan M. Passner;Hyung Don Ryoo;Leyi Shen;Richard S. Mann

  • Low affinity binding site clusters confer hox specificity and regulatory robustness.

    Justin Crocker;Namiko Abe;Lucrezia Rinaldi;Alistair P. McGregor

  • Functional specificity of a Hox protein mediated by the recognition of minor groove structure

    Rohit Joshi;Jonathan M. Passner;Remo Rohs;Remo Rohs;Rinku Jain

  • Hox specificity unique roles for cofactors and collaborators.

    Richard S. Mann;Katherine M. Lelli;Rohit Joshi

  • Control of antennal versus leg development in Drosophila

    Fernando Casares;Richard S. Mann

  • Functional dissection of ultrabithorax proteins in D. melanogaster

    Richard S. Mann;David S. Hogness

  • Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development

    M. Abu-Shaar;R.S. Mann

  • Disentangling the Many Layers of Eukaryotic Transcriptional Regulation

    Katherine M. Lelli;Matthew Slattery;Richard S. Mann

  • Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex.

    Hyung Don Ryoo;Thomas Marty;Fernando Casares;Markus Affolter

Frequent Co-Authors

Harmen J. Bussemaker
Harmen J. Bussemaker Columbia University
Barry Honig
Barry Honig Columbia University
Remo Rohs
Remo Rohs University of Southern California
Markus Affolter
Markus Affolter University of Basel
J. Spencer Johnston
J. Spencer Johnston Texas A&M University
Kevin P. White
Kevin P. White National University of Singapore
David L. Stern
David L. Stern Howard Hughes Medical Institute
Robb Krumlauf
Robb Krumlauf Stowers Institute for Medical Research
Daniel E. Neafsey
Daniel E. Neafsey Broad Institute
David J. Merritt
David J. Merritt University of Western Australia

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