D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 64 Citations 15,319 165 World Ranking 4379 National Ranking 105

Overview

What is she best known for?

The fields of study she is best known for:

  • Genetics
  • Cell membrane
  • Internal medicine

Her main research concerns Cell biology, Cadherin, Actin cytoskeleton, Adherens junction and Cell adhesion. Much of her study explores Cell biology relationship to Arp2/3 complex. Her Cadherin study incorporates themes from Cell signaling, Signal transduction, Catenin, Cell junction and Cell membrane.

Actin cytoskeleton is a subfield of Cytoskeleton that Alpha S. Yap explores. Her study looks at the relationship between Adherens junction and fields such as Epithelial polarity, as well as how they intersect with chemical problems. Her study in Cell adhesion is interdisciplinary in nature, drawing from both Contractility and Phosphatidylinositol 3-Kinases.

Her most cited work include:

  • Molecular and functional analysis of cadherin-based adherens junctions (703 citations)
  • Cadherins and cancer: how does cadherin dysfunction promote tumor progression? (578 citations)
  • The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn (515 citations)

What are the main themes of her work throughout her whole career to date?

Alpha S. Yap mostly deals with Cell biology, Cadherin, Adherens junction, Myosin and RHOA. Her studies in Cell biology integrate themes in fields like Cell, Cell adhesion, Actin cytoskeleton and Cytoskeleton. Her Cell adhesion study integrates concerns from other disciplines, such as Cell membrane and Cell–cell interaction.

The various areas that she examines in her Cadherin study include Catenin, Cell junction, Transfection, Cell adhesion molecule and Contractility. In Adherens junction, Alpha S. Yap works on issues like Signal transduction, which are connected to Cancer research. Her RHOA research incorporates elements of Confocal, Wild type, Signalling and Gene knockdown.

She most often published in these fields:

  • Cell biology (83.79%)
  • Cadherin (57.59%)
  • Adherens junction (31.03%)

What were the highlights of her more recent work (between 2015-2021)?

  • Cell biology (83.79%)
  • Cadherin (57.59%)
  • RHOA (25.52%)

In recent papers she was focusing on the following fields of study:

Alpha S. Yap mainly investigates Cell biology, Cadherin, RHOA, Myosin and Adherens junction. Her primary area of study in Cell biology is in the field of Actin. Within one scientific family, she focuses on topics pertaining to Wild type under Cadherin, and may sometimes address concerns connected to CDC42.

Her RHOA study combines topics in areas such as HEK 293 cells, Cell signaling and Immunoprecipitation. As part of one scientific family, Alpha S. Yap deals mainly with the area of Myosin, narrowing it down to issues related to the Confocal, and often Confocal microscopy. Her studies link Signal transduction with Adherens junction.

Between 2015 and 2021, her most popular works were:

  • Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity (145 citations)
  • Tensile Forces and Mechanotransduction at Cell-Cell Junctions. (131 citations)
  • Remodeling the zonula adherens in response to tension and the role of afadin in this response (101 citations)

In her most recent research, the most cited papers focused on:

  • Genetics
  • Cell biology
  • Cell membrane

Alpha S. Yap mainly focuses on Cell biology, Adherens junction, Cadherin, Contractility and RHOA. The concepts of her Cell biology study are interwoven with issues in Cell, Cell junction and Cytoskeleton. Her Adherens junction research is multidisciplinary, incorporating perspectives in Formins, Coronin and Myosin.

Alpha S. Yap focuses mostly in the field of Cadherin, narrowing it down to matters related to Cell adhesion and, in some cases, Endocytosis and Muscle contraction. The various areas that Alpha S. Yap examines in her Contractility study include MDia1, Vinculin, Cortactin and Actin. Her Signal transduction research integrates issues from Cancer research and Actin cytoskeleton.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Molecular and functional analysis of cadherin-based adherens junctions

Alpha S. Yap;William M. Brieher;Barry M. Gumbiner.
Annual Review of Cell and Developmental Biology (1997)

946 Citations

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

A Jeanes;C J Gottardi;A S Yap.
Oncogene (2008)

847 Citations

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn

Alpha S. Yap;Carien M. Niessen;Barry M. Gumbiner.
Journal of Cell Biology (1998)

795 Citations

Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics.

Tam Luan Le;Alpha S. Yap;Jennifer L. Stow.
Journal of Cell Biology (1999)

645 Citations

Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

Alpha S. Yap;William M. Brieher;Martin Pruschy;Barry M. Gumbiner.
Current Biology (1997)

436 Citations

Myosin 2 Is a Key Rho Kinase Target Necessary for the Local Concentration of E-Cadherin at Cell–Cell Contacts

Annette M. Shewan;Madhavi Maddugoda;Astrid Kraemer;Samantha J. Stehbens.
Molecular Biology of the Cell (2005)

382 Citations

Lateral dimerization is required for the homophilic binding activity of C-cadherin

William M. Brieher;Alpha S. Yap;Barry M. Gumbiner.
Journal of Cell Biology (1996)

381 Citations

E-cadherin Homophilic Ligation Directly Signals through Rac and Phosphatidylinositol 3-Kinase to Regulate Adhesive Contacts

Eva M. Kovacs;Radiya G. Ali;Ailsa J. McCormack;Alpha S. Yap.
Journal of Biological Chemistry (2002)

370 Citations

Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation

Carien M. Niessen;Deborah Leckband;Alpha S. Yap.
Physiological Reviews (2011)

369 Citations

E-cadherin junctions as active mechanical integrators in tissue dynamics

Thomas Lecuit;Alpha S Yap.
Nature Cell Biology (2015)

365 Citations

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