Her main research concerns Cell biology, Cadherin, Actin cytoskeleton, Adherens junction and Cell adhesion. Much of her study explores Cell biology relationship to Arp2/3 complex. Her Cadherin study incorporates themes from Cell signaling, Signal transduction, Catenin, Cell junction and Cell membrane.
Actin cytoskeleton is a subfield of Cytoskeleton that Alpha S. Yap explores. Her study looks at the relationship between Adherens junction and fields such as Epithelial polarity, as well as how they intersect with chemical problems. Her study in Cell adhesion is interdisciplinary in nature, drawing from both Contractility and Phosphatidylinositol 3-Kinases.
Alpha S. Yap mostly deals with Cell biology, Cadherin, Adherens junction, Myosin and RHOA. Her studies in Cell biology integrate themes in fields like Cell, Cell adhesion, Actin cytoskeleton and Cytoskeleton. Her Cell adhesion study integrates concerns from other disciplines, such as Cell membrane and Cell–cell interaction.
The various areas that she examines in her Cadherin study include Catenin, Cell junction, Transfection, Cell adhesion molecule and Contractility. In Adherens junction, Alpha S. Yap works on issues like Signal transduction, which are connected to Cancer research. Her RHOA research incorporates elements of Confocal, Wild type, Signalling and Gene knockdown.
Alpha S. Yap mainly investigates Cell biology, Cadherin, RHOA, Myosin and Adherens junction. Her primary area of study in Cell biology is in the field of Actin. Within one scientific family, she focuses on topics pertaining to Wild type under Cadherin, and may sometimes address concerns connected to CDC42.
Her RHOA study combines topics in areas such as HEK 293 cells, Cell signaling and Immunoprecipitation. As part of one scientific family, Alpha S. Yap deals mainly with the area of Myosin, narrowing it down to issues related to the Confocal, and often Confocal microscopy. Her studies link Signal transduction with Adherens junction.
Alpha S. Yap mainly focuses on Cell biology, Adherens junction, Cadherin, Contractility and RHOA. The concepts of her Cell biology study are interwoven with issues in Cell, Cell junction and Cytoskeleton. Her Adherens junction research is multidisciplinary, incorporating perspectives in Formins, Coronin and Myosin.
Alpha S. Yap focuses mostly in the field of Cadherin, narrowing it down to matters related to Cell adhesion and, in some cases, Endocytosis and Muscle contraction. The various areas that Alpha S. Yap examines in her Contractility study include MDia1, Vinculin, Cortactin and Actin. Her Signal transduction research integrates issues from Cancer research and Actin cytoskeleton.
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Molecular and functional analysis of cadherin-based adherens junctions
Alpha S. Yap;William M. Brieher;Barry M. Gumbiner.
Annual Review of Cell and Developmental Biology (1997)
Cadherins and cancer: how does cadherin dysfunction promote tumor progression?
A Jeanes;C J Gottardi;A S Yap.
The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn
Alpha S. Yap;Carien M. Niessen;Barry M. Gumbiner.
Journal of Cell Biology (1998)
Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics.
Tam Luan Le;Alpha S. Yap;Jennifer L. Stow.
Journal of Cell Biology (1999)
Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function
Alpha S. Yap;William M. Brieher;Martin Pruschy;Barry M. Gumbiner.
Current Biology (1997)
Myosin 2 Is a Key Rho Kinase Target Necessary for the Local Concentration of E-Cadherin at Cell–Cell Contacts
Annette M. Shewan;Madhavi Maddugoda;Astrid Kraemer;Samantha J. Stehbens.
Molecular Biology of the Cell (2005)
Lateral dimerization is required for the homophilic binding activity of C-cadherin
William M. Brieher;Alpha S. Yap;Barry M. Gumbiner.
Journal of Cell Biology (1996)
E-cadherin Homophilic Ligation Directly Signals through Rac and Phosphatidylinositol 3-Kinase to Regulate Adhesive Contacts
Eva M. Kovacs;Radiya G. Ali;Ailsa J. McCormack;Alpha S. Yap.
Journal of Biological Chemistry (2002)
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation
Carien M. Niessen;Deborah Leckband;Alpha S. Yap.
Physiological Reviews (2011)
E-cadherin junctions as active mechanical integrators in tissue dynamics
Thomas Lecuit;Alpha S Yap.
Nature Cell Biology (2015)
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