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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
21439
World Ranking
10552
National Ranking
288

Overview

Ygal Haupt is affiliated with the Peter MacCallum Cancer Centre in Australia. Their research spans multiple fields within medicine, focusing primarily on oncology, molecular biology, and pulmonary and respiratory medicine. They have contributed substantial work to areas including cancer-related molecular pathways, cancer immunotherapy and biomarkers, and the treatment and diagnosis of prostate and advanced breast cancers.

Their recent publications include:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023" (2023) published in Cell Death and Differentiation
  • "Sex disparities matter in cancer development and therapy" (2021) published in Nature reviews. Cancer
  • "P53: A Guardian of Immunity Becomes Its Saboteur through Mutation" (2020) published in International Journal of Molecular Sciences
  • "High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot" (2020) published in Journal for ImmunoTherapy of Cancer
  • "MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer" (2020) published in Breast Cancer Research

Frequent collaborators include:

  • Sue Haupt (28 coauthored papers)
  • Franco Caramia (11 coauthored papers)
  • Scott Williams (11 coauthored papers)
  • Simon P. Keam (11 coauthored papers)
  • Paul J. Neeson (10 coauthored papers)

Their work is frequently published in venues such as:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature (11 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Journal for ImmunoTherapy of Cancer (2 publications)
  • Cancers (2 publications)
  • Journal of Clinical Oncology (2 publications)

Ygal Haupt's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their subfields of study focus on:

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Immunology
  • Genetics

Main research topics covered by their publications are:

  • Prostate Cancer Treatment and Research
  • Cancer-related Molecular Pathways
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Epigenetics and DNA Methylation
  • Prostate Cancer Diagnosis and Treatment
  • Advanced Breast Cancer Therapies

Best Publications

  • Mdm2 promotes the rapid degradation of p53

    Ygal Haupt;Ruth Maya;Anat Kazaz;Moshe Oren

  • Apoptosis - the p53 network

    Susan Haupt;Michael Berger;Zehavit Goldberg;Ygal Haupt

  • The cellular response to p53: the decision between life and death

    Ronit Vogt Sionov;Ygal Haupt

  • Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

    Y Haupt;S Rowan;E Shaulian;K H Vousden

  • Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice

    Ygal Haupt;Warren S. Alexander;Gina Barri;S. Peter Klinken

  • c-Jun and p53 activity is modulated by SUMO-1 modification.

    Stefan Müller;Michael Berger;François Lehembre;Jacob-S. Seeler

  • CRITICAL ROLE FOR SER20 OF HUMAN P53 IN THE NEGATIVE REGULATION OF P53 BY MDM2

    Tamar Unger;Tamar Juven-Gershon;Eli Moallem;Michael Berger

  • Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.

    S Rowan;R L Ludwig;Y Haupt;S Bates

  • A functional p53-responsive intronic promoter is contained within the human mdm2 gene

    Arie Zauberman;Deborah Flusberg;Ygal Haupt;Yaacov Barak

  • A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis.

    P Friedlander;Y Haupt;C Prives;M Oren

  • MDM4 is a key therapeutic target in cutaneous melanoma

    Agnieszka Gembarska;Agnieszka Gembarska;Flavie Luciani;Flavie Luciani;Clare Fedele;Clare Fedele;Elisabeth A Russell

  • Clinical Overview of MDM2/X-Targeted Therapies

    Andrew Burgess;Kee Ming Chia;Sue Haupt;David Thomas;David Thomas

  • Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis.

    Shashank Masaldan;Sharnel A.S. Clatworthy;Cristina Gamell;Peter M. Meggyesy

  • Cell type-specific inhibition of p53-mediated apoptosis by mdm2.

    Y Haupt;Y Barak;M Oren

  • Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

    David Shi Hao Liu;Cuong Phu Duong;Sue Haupt;Karen G Montgomery

  • AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy

    Megan Astle;Katherine Hannan;Puiyee Ng;Rachel Lee

  • Tumour suppression by p53: the importance of apoptosis and cellular senescence.

    Valentina Zuckerman;Kamil Wolyniec;Ronit V Sionov;Sue Haupt

  • Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

    Zehavit Goldberg;Ronit Vogt Sionov;Michael Berger;Yaara Zwang

  • bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis.

    Y Haupt;M L Bath;A W Harris;J M Adams

  • Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

    Tamar Unger;Ronit Vogt Sionov;Eli Moallem;Carole L Yee

Frequent Co-Authors

Stephen B. Fox
Stephen B. Fox Peter MacCallum Cancer Centre
Moshe Oren
Moshe Oren Weizmann Institute of Science
James G. Kench
James G. Kench Royal Prince Alfred Hospital
Richard B. Pearson
Richard B. Pearson Peter MacCallum Cancer Centre
Carleen Cullinane
Carleen Cullinane Peter MacCallum Cancer Centre
Marco J. Herold
Marco J. Herold Walter and Eliza Hall Institute of Medical Research
Wayne D. Tilley
Wayne D. Tilley University of Adelaide
Robin L. Anderson
Robin L. Anderson La Trobe University
Yong-hui Jiang
Yong-hui Jiang Yale School of Medicine
Wayne A. Phillips
Wayne A. Phillips Peter MacCallum Cancer Centre

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