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Biology and Biochemistry

D-Index
56
Citations
11754
World Ranking
14393
National Ranking
395

Overview

Wayne A. Phillips is affiliated with the Peter MacCallum Cancer Centre in Australia. Their research primarily spans medicine and biochemistry, genetics, and molecular biology, with a significant number of publications in these fields.

The scientist's work delves into several subfields, including molecular biology, oncology, surgery, cancer research, and immunology. Their main research topics cover a range of cancer-related areas:

  • Cancer Genomics and Diagnostics
  • Esophageal Cancer Research and Treatment
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Ferroptosis and cancer prognosis

Wayne A. Phillips has published frequently in several key journals and venues. Notably, these include:

  • Molecular Cancer Therapeutics
  • Diseases of the Esophagus
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Annals of Surgical Oncology

Among their more recent publications are the following papers:

  • "Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction," 2022, Science Advances
  • "SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status," 2021, Molecular Cancer Therapeutics
  • "YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells," 2023, Nature Communications
  • "Potential Clinical Utility of a Targeted Circulating Tumor DNA Assay in Esophageal Adenocarcinoma," 2021, Annals of Surgery
  • "GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma," 2020, The Journal of Pathology

Wayne A. Phillips has collaborated extensively with a number of researchers, including:

  • Nicholas J. Clemons
  • Kenji M. Fujihara
  • Cuong Duong
  • Julia V. Milne
  • Carlos S. Cabalag

Best Publications

  • Mutation of the PIK3CA gene in ovarian and breast cancer.

    Ian G. Campbell;Sarah E. Russell;David Y. H. Choong;Karen G. Montgomery

  • The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.

    Amanda J. Philp;Ian G. Campbell;Christine Leet;Elizabeth Vincan

  • PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor–positive breast cancer

    Sherene Loi;Sherene Loi;Sherene Loi;Benjamin Haibe-Kains;Samira Majjaj;Francoise Lallemand

  • Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity

    Alexandra Van Keymeulen;May Yin Lee;Marielle Ousset;Sylvain Brohée

  • A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma

    Eric A. Collisson;Christy L. Trejo;Jillian M. Silva;Shenda Gu

  • Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis

    Katia Nones;Katia Nones;Nicola Waddell;Nicola Waddell;Nicci Wayte;Ann-Marie Patch

  • Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

    David Shi Hao Liu;Cuong Phu Duong;Sue Haupt;Karen G Montgomery

  • Lipopolysaccharide priming of human neutrophils for an enhanced respiratory burst. Role of intracellular free calcium.

    J R Forehand;M J Pabst;W A Phillips;R B Johnston

  • Targeting PI3 Kinase/AKT/mTOR Signaling in Cancer

    Karen E Sheppard;Kathryn M Kinross;Benjamin Solomon;Richard B Pearson

  • An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.

    Kathryn M Kinross;Karen G Montgomery;Margarete Kleinschmidt;Paul Waring

  • Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers

    Åslaug Helland;Michael S. Anglesio;Michael S. Anglesio;Joshy George;Joshy George;Prue A. Cowin

  • Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A.

    S Majumdar;M W Rossi;T Fujiki;W A Phillips

  • The Ras/Mitogen-Activated Protein Kinase Pathway Inhibitor and Likely Tumor Suppressor Proteins, Sprouty 1 and Sprouty 2 Are Deregulated in Breast Cancer

    Ting Ling Lo;Permeen Yusoff;Chee Wai Fong;Ke Guo

  • Differential hypermethylation of SOCS genes in ovarian and breast carcinomas

    Kate D Sutherland;Geoffrey J Lindeman;David Y H Choong;Sergio Wittlin

  • Aberrant Epithelial-Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

    David H. Wang;Nicholas J. Clemons;Tomoharu Miyashita;Adam J. Dupuy

  • Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma.

    Steven P. Rockman;Scott A. Currie;Marianne Ciavarella;Elizabeth Vincan

  • Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

    Sandra D. Castillo;Elena Tzouanacou;Elena Tzouanacou;May Zaw-Thin;Inma M. Berenjeno

  • Combined CDK4/6 and PI3Kα Inhibition Is Synergistic and Immunogenic in Triple-Negative Breast Cancer

    Zhi Ling Teo;Zhi Ling Teo;Stephanie Versaci;Sathana Dushyanthen;Franco Caramia

  • Predicting pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review.

    J. E. Ryan;J. E. Ryan;Satish K Warrier;A. C. Lynch;Robert G Ramsay;Robert G Ramsay

  • Priming of neutrophils and macrophages for enhanced release of superoxide anion by the calcium ionophore ionomycin. Implications for regulation of the respiratory burst.

    T H Finkel;M J Pabst;H Suzuki;L A Guthrie

Frequent Co-Authors

Robert G. Ramsay
Robert G. Ramsay Peter MacCallum Cancer Centre
Richard B. Pearson
Richard B. Pearson Peter MacCallum Cancer Centre
Grant A. McArthur
Grant A. McArthur Peter MacCallum Cancer Centre
Ian G. Campbell
Ian G. Campbell Peter MacCallum Cancer Centre
Carleen Cullinane
Carleen Cullinane Peter MacCallum Cancer Centre
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Martin McMahon
Martin McMahon Huntsman Cancer Institute
John A. Hamilton
John A. Hamilton University of Melbourne
Christina Anne Mitchell
Christina Anne Mitchell Monash University
Ygal Haupt
Ygal Haupt Peter MacCallum Cancer Centre

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