What is he best known for?
The fields of study he is best known for:
His primary areas of study are Cancer research, Melanoma, MAPK/ERK pathway, Cell biology and V600E.
Martin McMahon has included themes like Autophagy, Pancreatic cancer, Carcinogenesis, Tumor suppressor gene and Immunology in his Cancer research study.
His Melanoma research is multidisciplinary, incorporating elements of Cancer and PTEN.
His MAPK/ERK pathway research entails a greater understanding of Signal transduction.
As a part of the same scientific study, he usually deals with the Signal transduction, concentrating on Receptor and frequently concerns with STAT6.
The study incorporates disciplines such as Cyclin-dependent kinase and Cell cycle checkpoint in addition to Cell biology.
His most cited work include:
- Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis (1289 citations)
- Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK (1028 citations)
- BrafV600E cooperates with Pten loss to induce metastatic melanoma (829 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cancer research, MAPK/ERK pathway, Cell biology, Melanoma and Signal transduction.
The Cancer research study combines topics in areas such as Cancer, Protein kinase B, V600E, Immunology and PI3K/AKT/mTOR pathway.
Within one scientific family, he focuses on topics pertaining to Protein kinase A under MAPK/ERK pathway, and may sometimes address concerns connected to Molecular biology.
His study in Cell biology is interdisciplinary in nature, drawing from both Cell cycle and Cell growth.
His research on Melanoma also deals with topics like
- PTEN and related Gene silencing,
- Drug resistance which is related to area like Pharmacology.
His studies deal with areas such as Cell culture, Endocrinology, Cellular differentiation, Cytokine and Apoptosis as well as Signal transduction.
He most often published in these fields:
- Cancer research (62.78%)
- MAPK/ERK pathway (35.87%)
- Cell biology (29.15%)
What were the highlights of his more recent work (between 2016-2021)?
- Cancer research (62.78%)
- Melanoma (34.98%)
- Cancer (18.39%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cancer research, Melanoma, Cancer, Autophagy and MAPK/ERK pathway.
His Cancer research research is multidisciplinary, incorporating perspectives in PI3K/AKT/mTOR pathway, Signal transduction, Trametinib, Gene silencing and Kinase.
His PI3K/AKT/mTOR pathway study combines topics in areas such as Protein kinase B, Lipid signaling, Immunology and Cell growth.
Martin McMahon interconnects Focal adhesion, Mutant, GNAQ, Targeted therapy and Metastasis in the investigation of issues within Melanoma.
His research in Mutant intersects with topics in Effector and Cell biology.
His work carried out in the field of MAPK/ERK pathway brings together such families of science as Bioinformatics, Carcinogenesis, Phenotype, Noonan syndrome and Germline.
Between 2016 and 2021, his most popular works were:
- Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. (180 citations)
- Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. (180 citations)
- BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis (32 citations)
In his most recent research, the most cited papers focused on:
Cancer research, Melanoma, MAPK/ERK pathway, Autophagy and Trametinib are his primary areas of study.
His Cancer research research is multidisciplinary, incorporating elements of Cancer, Colorectal cancer, PI3K/AKT/mTOR pathway, Signal transduction and Gene silencing.
His studies in Cancer integrate themes in fields like Cell, Lung cancer and Kinase.
His Signal transduction research incorporates themes from Mutation and Cancer cell.
His work is dedicated to discovering how Melanoma, Metastasis are connected with Oncology, Retrospective cohort study and Single Center and other disciplines.
His research links Treatment strategy with MAPK/ERK pathway.
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