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Simon J. Cook

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
17537
World Ranking
7748
National Ranking
601

Simon J. Cook publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Simon J. Cook sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 147 publications — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Simon J. Cook D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Simon J. Cook sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 68 D-Index — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Simon J. Cook is affiliated with the Babraham Institute in the United Kingdom. Their research primarily falls within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, key subfields include Molecular Biology, Immunology, Cancer Research, Computational Theory and Mathematics, and Oncology.

The scientist's work covers several main topics, including:

  • Melanoma and MAPK Pathways
  • Computational Drug Discovery Methods
  • Epigenetics and DNA Methylation
  • Protein Kinase Regulation and GTPase Signaling
  • Cytokine Signaling Pathways and Interactions
  • Cancer, Hypoxia, and Metabolism
  • Immune cells in cancer

Simon J. Cook has published extensively, with recent papers focusing on signaling pathways and kinase regulation among other topics. Selected recent publications include:

  • "Inhibitory feedback control of NF-κB signalling in health and disease," 2021, Biochemical Journal
  • "CDK1, the Other 'Master Regulator' of Autophagy," 2020, Trends in Cell Biology
  • "Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors," 2020, Nature Communications
  • "Environmental Sustainability and Supply Resilience of Cobalt," 2022, Sustainability
  • "Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for...," 2020, Biochemical Society Transactions

Frequent collaborators with Simon J. Cook include Pamela A. Lochhead, Andrew M. Kidger, Rebecca Gilley, Julie A. Tucker, and Kathryn Balmanno, each contributing to multiple joint publications.

Common venues for publication encompass:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemical Journal
  • Nature Communications
  • EMBO Reports
  • Trends in Cell Biology

Best Publications

  • Inhibition by cAMP of Ras-dependent activation of Raf

    Simon J. Cook;Frank McCormick

  • Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival.

    H. Llewelyn Roderick;H. Llewelyn Roderick;Simon J. Cook

  • Characterization of Two Alternately Spliced Forms of Phospholipase D1 ACTIVATION OF THE PURIFIED ENZYMES BY PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE, ADP-RIBOSYLATION FACTOR, AND RHO FAMILY MONOMERIC GTP-BINDING PROTEINS AND PROTEIN KINASE C-α

    Scott M. Hammond;John M. Jenco;Shigeru Nakashima;Karen Cadwallader

  • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

    Rebecca Ley;Kathryn Balmanno;Kathryn Hadfield;Claire R. Weston

  • MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.

    Christopher J. Caunt;Matthew J. Sale;Paul D. Smith;Simon J. Cook

  • Tumour cell survival signalling by the ERK1/2 pathway.

    K Balmanno;S J Cook

  • RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts.

    S J Cook;B Rubinfeld;I Albert;F McCormick

  • FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

    Gabriella Ficz;Timothy A. Hore;Fátima Santos;Heather J. Lee

  • The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

    Nicola J. Darling;Simon J. Cook

  • Regulatory phosphorylation of Bim: sorting out the ERK from the JNK.

    R Ley;K E Ewings;K Hadfield;S J Cook

  • Paclitaxel-Induced Nuclear Translocation of FOXO3a in Breast Cancer Cells Is Mediated by c-Jun NH2-Terminal Kinase and Akt

    Andrew Sunters;Patricia A. Madureira;Karen M. Pomeranz;Muriel Aubert

  • Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells.

    Kathryn Balmanno;Simon J Cook

  • The Selective Protein Kinase C Inhibitor, Ro-31-8220, Inhibits Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression, Induces c-Jun Expression, and Activates Jun N-terminal Kinase

    Jerlyn Beltman;Frank McCormick;Simon J. Cook

  • The Repertoire of Fos and Jun Proteins Expressed during the G1 Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase Activation

    Simon J. Cook;Simon J. Cook;Natasha Aziz;Martin McMahon

  • Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover.

    Rebecca Ley;Katherine E. Ewings;Kathryn Hadfield;Elizabeth Howes

  • Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-O-tetradecanoylphorbol 13-acetate) stimulate choline generation in Swiss 3T3 cells by a common mechanism.

    S J Cook;M J O Wakelam

  • Amplification of the Driving Oncogene, KRAS or BRAF, Underpins Acquired Resistance to MEK1/2 Inhibitors in Colorectal Cancer Cells

    Annette S. Little;Kathryn Balmanno;Matthew J. Sale;Scott Newman

  • De-regulated FGF receptors as therapeutic targets in cancer.

    Victoria Knights;Simon J. Cook

  • FGF signalling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency

    Gabriella Ficz;Timothy A Hore;Fatima Santos;Heather J Lee

  • Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection.

    Parjeet K. Boughan;Richard H. Argent;Mathilde Body-Malapel;Jong-Hwan Park

Frequent Co-Authors

Frank McCormick
Frank McCormick University of California, San Francisco
Wolf Reik
Wolf Reik Babraham Institute
Paul D. Smith
Paul D. Smith AstraZeneca (United Kingdom)
Martin McMahon
Martin McMahon Huntsman Cancer Institute
Simon Andrews
Simon Andrews Babraham Institute
Myriam Hemberger
Myriam Hemberger University of Calgary
Wendy Dean
Wendy Dean Babraham Institute
Julio Saez-Rodriguez
Julio Saez-Rodriguez Heidelberg University
H. Llewelyn Roderick
H. Llewelyn Roderick KU Leuven
Jörn Walter
Jörn Walter Saarland University

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Best Scientists Citing Simon J. Cook

Wolf Reik

Wolf Reik

Babraham Institute

Publications: 74

Michael A. Frohman

Michael A. Frohman

Stony Brook University

Publications: 43

John H. Exton

John H. Exton

Vanderbilt University

Publications: 38

Andreas Strasser

Andreas Strasser

Walter and Eliza Hall Institute of Medical Research

Publications: 37

Eric Lam

Eric Lam

Sun Yat-sen University

Publications: 34

Andrew J. Morris

Andrew J. Morris

University of Kentucky

Publications: 32

Florian Lang

Florian Lang

University of Tübingen

Publications: 30

Steven Grant

Steven Grant

Virginia Commonwealth University

Publications: 27

Gavin Kelsey

Gavin Kelsey

Babraham Institute

Publications: 24

Gregory R. Monteith

Gregory R. Monteith

University of Queensland

Publications: 23

Paul Dent

Paul Dent

Virginia Commonwealth University

Publications: 23

Sung Ho Ryu

Sung Ho Ryu

Pohang University of Science and Technology

Publications: 22

Geert Bultynck

Geert Bultynck

KU Leuven

Publications: 22

Austin Smith

Austin Smith

University of Exeter

Publications: 22

Myriam Hemberger

Myriam Hemberger

University of Calgary

Publications: 22

Martin R. Turner

Martin R. Turner

University of Oxford

Publications: 20

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