D-Index & Metrics Best Publications
H. Llewelyn Roderick

H. Llewelyn Roderick

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 49 Citations 19,288 92 World Ranking 10692 National Ranking 190

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Endoplasmic reticulum

His main research concerns Cell biology, Endoplasmic reticulum, Calcium signaling, Receptor and Signalling. His Cell biology research is multidisciplinary, incorporating perspectives in Apoptosis, Programmed cell death and Calcium. In the subject of general Endoplasmic reticulum, his work in Golgi apparatus is often linked to Autophagy-Related Protein-1 Homolog, thereby combining diverse domains of study.

His studies in Calcium signaling integrate themes in fields like Neuroscience and Voltage-dependent calcium channel. His Signalling research incorporates elements of Cancer cell, Cancer, Cancer cell proliferation and Second messenger system. As part of the same scientific family, he usually focuses on Intracellular, concentrating on STIM2 and intersecting with Store-operated calcium entry and SOC channels.

His most cited work include:

  • Calcium signalling: dynamics, homeostasis and remodelling. (4034 citations)
  • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum (1276 citations)
  • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum (1276 citations)

What are the main themes of his work throughout his whole career to date?

H. Llewelyn Roderick mainly investigates Cell biology, Receptor, Calcium signaling, Internal medicine and Calcium. The Cell biology study combines topics in areas such as Apoptosis and Biochemistry. His Inositol study, which is part of a larger body of work in Receptor, is frequently linked to T-cell receptor, bridging the gap between disciplines.

His study focuses on the intersection of Calcium signaling and fields such as Depolarization with connections in the field of Cardiac function curve. His research integrates issues of Endocrinology and Cardiology in his study of Internal medicine. His Endoplasmic reticulum research incorporates themes from Programmed cell death and Transfection.

He most often published in these fields:

  • Cell biology (78.17%)
  • Receptor (43.66%)
  • Calcium signaling (44.37%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (78.17%)
  • Myocyte (30.99%)
  • Ryanodine receptor (36.62%)

In recent papers he was focusing on the following fields of study:

H. Llewelyn Roderick mainly focuses on Cell biology, Myocyte, Ryanodine receptor, Internal medicine and Epigenome. MAPK/ERK pathway and Calcium signaling are among the areas of Cell biology where H. Llewelyn Roderick concentrates his study. His research in Myocyte intersects with topics in Stimulation, Signal transduction, Endothelin 1 and Heart failure.

His studies deal with areas such as Biophysics and Live cell imaging as well as Ryanodine receptor. His Internal medicine research includes themes of Endocrinology, Ca2+/calmodulin-dependent protein kinase and Cardiology. His Calcium research focuses on NFAT and how it relates to Receptor and Inositol.

Between 2015 and 2021, his most popular works were:

  • Myofibroblast Phenotype and Reversibility of Fibrosis in Patients With End-Stage Heart Failure (43 citations)
  • Global fibroblast activation throughout the left ventricle but localized fibrosis after myocardial infarction (23 citations)
  • Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors. (18 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Apoptosis

Myocyte, MAPK/ERK pathway, Endocrinology, Internal medicine and Lysyl oxidase are his primary areas of study. His study with Myocyte involves better knowledge in Cell biology. His Cell biology study combines topics in areas such as RNA, Membrane transport and Gene isoform.

The various areas that H. Llewelyn Roderick examines in his MAPK/ERK pathway study include Cancer cell, Growth factor receptor, Intracellular and Cell growth. As a part of the same scientific study, H. Llewelyn Roderick usually deals with the Endocrinology, concentrating on Ryanodine receptor and frequently concerns with Ventricular remodeling and Heart metabolism. His work in Heart failure tackles topics such as Sarcolemma which are related to areas like Calcium signaling.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Calcium signalling: dynamics, homeostasis and remodelling.

Michael J. Berridge;Martin D. Bootman;H. Llewelyn Roderick.
Nature Reviews Molecular Cell Biology (2003)

5881 Citations

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

Elizabeth L. Axe;Simon A. Walker;Maria Manifava;Priya Chandra.
Journal of Cell Biology (2008)

1713 Citations

2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release.

Martin D. Bootman;Tony J. Collins;Lauren Mackenzie;H. Llewelyn Roderick.
The FASEB Journal (2002)

768 Citations

Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival.

H. Llewelyn Roderick;H. Llewelyn Roderick;Simon J. Cook.
Nature Reviews Cancer (2008)

673 Citations

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate

Rui-rui Chen;Ignacio Valencia;Fei Zhong;Karen S McColl.
Journal of Cell Biology (2004)

448 Citations

ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.

Jason D. Oliver;H. Llewelyn Roderick;David H. Llewellyn;Stephen High.
Molecular Biology of the Cell (1999)

379 Citations

2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels

Claire M. Peppiatt;Tony J. Collins;Lauren Mackenzie;Stuart J. Conway.
Cell Calcium (2003)

354 Citations

Calcium signalling: more messengers, more channels, more complexity

Martin D Bootman;Michael J Berridge;H.Llewelyn Roderick.
Current Biology (2002)

333 Citations

Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells. A Potential Mechanism in Atherosclerotic Plaque Destabilization

Alexandra E. Ewence;Martin D. Bootman;H. Llewelyn Roderick;Jeremy N. Skepper.
Circulation Research (2008)

304 Citations

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

Yi Ping Rong;Geert Bultynck;Ademuyiwa S. Aromolaran;Fei Zhong.
Proceedings of the National Academy of Sciences of the United States of America (2009)

297 Citations

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