What is he best known for?
The fields of study he is best known for:
Marek Michalak mostly deals with Calreticulin, Endoplasmic reticulum, Cell biology, Biochemistry and Calnexin.
His Calreticulin research integrates issues from Phagocytosis, Molecular biology, Thapsigargin, Protein structure and Glucocorticoid receptor.
His work carried out in the field of Endoplasmic reticulum brings together such families of science as Calcium-binding protein and Signal transduction.
His work focuses on many connections between Biochemistry and other disciplines, such as Lumen, that overlap with his field of interest in Secretion.
His Calnexin research includes themes of Antigen, MHC class I, Transporter associated with antigen processing, Tapasin and Major histocompatibility complex.
In the subject of general Unfolded protein response, his work in ATF6 is often linked to Pressure overload, thereby combining diverse domains of study.
His most cited work include:
- Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte (981 citations)
- IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response (847 citations)
- Calreticulin: one protein, one gene, many functions. (664 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Endoplasmic reticulum, Cell biology, Calreticulin, Biochemistry and Unfolded protein response.
As a part of the same scientific study, Marek Michalak usually deals with the Endoplasmic reticulum, concentrating on Calcium-binding protein and frequently concerns with Calcium in biology.
Marek Michalak combines topics linked to Cell with his work on Cell biology.
His work deals with themes such as Binding protein, Transcription factor, Immunology, Molecular biology and Internal medicine, which intersect with Calreticulin.
His Molecular biology study combines topics from a wide range of disciplines, such as Regulation of gene expression and KDEL.
His studies deal with areas such as Myocyte and Skeletal muscle as well as Calsequestrin.
He most often published in these fields:
- Endoplasmic reticulum (62.04%)
- Cell biology (61.31%)
- Calreticulin (55.84%)
What were the highlights of his more recent work (between 2012-2021)?
- Cell biology (61.31%)
- Endoplasmic reticulum (62.04%)
- Unfolded protein response (20.80%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Endoplasmic reticulum, Unfolded protein response, Calreticulin and Calnexin.
His Cell biology study integrates concerns from other disciplines, such as Cell and Transcription factor.
His Endoplasmic reticulum research is included under the broader classification of Biochemistry.
His Unfolded protein response research is multidisciplinary, incorporating elements of XBP1, Proteostasis, Signal transduction and Programmed cell death.
His study looks at the relationship between Calreticulin and topics such as Cancer research, which overlap with Pancreatic cancer.
His Calnexin course of study focuses on Experimental autoimmune encephalomyelitis and Sensitization and Transcellular.
Between 2012 and 2021, his most popular works were:
- Ca2+ homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling. (226 citations)
- Endoplasmic reticulum stress associated responses in cancer (128 citations)
- Coping with Endoplasmic Reticulum Stress in the Cardiovascular System (112 citations)
In his most recent research, the most cited papers focused on:
Marek Michalak focuses on Cell biology, Endoplasmic reticulum, Unfolded protein response, Calreticulin and Biochemistry.
His study involves Chaperone, Extracellular, Proteostasis, Calnexin and Homeostasis, a branch of Cell biology.
His Endoplasmic reticulum research incorporates elements of Endocrinology, Bioinformatics, Transcription factor, Reticular connective tissue and Internal medicine.
His Unfolded protein response study combines topics from a wide range of disciplines, such as Cell, XBP1, Protein folding, Calcium signaling and Programmed cell death.
His Calreticulin study incorporates themes from Heart failure, Saccharomyces cerevisiae, Downregulation and upregulation, Immunology and Fibrosis.
His Biochemistry research includes themes of Molecular biology and Computational biology.
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