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Marek Michalak

Marek Michalak

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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
30058
World Ranking
2545
National Ranking
77

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2007 - Fellow of the Royal Society of Canada Academy of Science

Overview

Marek Michalak is affiliated with the University of Alberta in Canada and has a research focus that spans several interrelated scientific areas. Their main fields of study include Biochemistry, Genetics and Molecular Biology with 81 publications, and Medicine with 53 publications.

Their work concentrates on specific subfields such as Molecular Biology, Cell Biology, Epidemiology, Physiology, and Sensory Systems. The primary topics covered in their research include:

  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Ion Channels and Receptors
  • Cancer-related gene regulation
  • Ion channel regulation and function
  • RNA modifications and cancer
  • Calcium signaling and nucleotide metabolism

Marek Michalak has published extensively in scientific journals with the most frequent venues being:

  • Cells
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • Scientific Reports
  • Cell Calcium
  • Biology

Among recent papers authored or co-authored by Michalak are:

  • LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes, 2020, Molecular Cancer
  • Calcium signaling and endoplasmic reticulum stress, 2021, International review of cell and molecular biology
  • TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer, 2020, Autophagy
  • Calnexin, More Than Just a Molecular Chaperone, 2023, Cells
  • Calsequestrin. Structure, function, and evolution, 2020, Cell Calcium

They have collaborated frequently with other researchers, including:

  • Jingfeng Tang (26 publications)
  • Xing-Zhen Chen (23 publications)
  • Declan W. Ali (21 publications)
  • Cefan Zhou (20 publications)
  • Luis B. Agellon (14 publications)

Michalak is also an author of book publications, notably:

  • Cellular Biology of the Endoplasmic Reticulum, published by Springer Science+Business Media in 2021

Their academic recognition includes the award of Fellow of the Royal Society of Canada in 2007 by the Academy of Science.

Best Publications

  • Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte

    Shyra J. Gardai;Kathleen A. McPhillips;S. Courtney Frasch;William J. Janssen

  • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

    Kyungho Lee;Witoon Tirasophon;Xiaohua Shen;Marek Michalak

  • Calreticulin: one protein, one gene, many functions.

    Marek Michalak;Elaine F. Corbett;Nasrin Mesaeli;Kimitoshi Nakamura

  • Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum

    Marek Michalak;Jody Groenendyk;Eva Szabo;Leslie I. Gold

  • Calreticulin Is Essential for Cardiac Development

    Nasrin Mesaeli;Kimitoshi Nakamura;Elena Zvaritch;Peter Dickie

  • Ca2+ homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling.

    Joachim Krebs;Luis B. Agellon;Marek Michalak

  • Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulum

    M Michalak;J.M Robert Parker;M Opas

  • Molecular cloning of the high affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum.

    L. Fliegel;K. Burns;D. H. Maclennan;R. A. F. Reithmeier

  • Modulation of gene expression by calreticulin binding to the glucocorticoid receptor

    K Burns;B Duggan;E A Atkinson;K S Famulski

  • Calreticulin: non-endoplasmic reticulum functions in physiology and disease

    Leslie I. Gold;Paul Eggleton;Mariya T. Sweetwyne;Lauren B. Van Duyn

  • Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis

    Kimitoshi Nakamura;Kimitoshi Nakamura;Ella Bossy-Wetzel;Kimberly Burns;Kimberly Burns;Marc P. Fadel

  • Expression of calreticulin in Escherichia coli and identification of its Ca2+ binding domains.

    S Baksh;M Michalak

  • Enhanced Catalysis of Ribonuclease B Folding by the Interaction of Calnexin or Calreticulin with ERp57

    André Zapun;André Zapun;Nigel J. Darby;Daniel C. Tessier;Marek Michalak

  • The ins and outs of calreticulin: from the ER lumen to the extracellular space.

    Steven Johnson;Marek Michalak;Michal Opas;Paul Eggleton

  • Functional specialization of calreticulin domains.

    Kimitoshi Nakamura;Anna Zuppini;Serge Arnaudeau;Jeffery Lynch

  • Biology of Endoplasmic Reticulum Stress in the Heart

    Jody Groenendyk;Pradeep Kumar Sreenivasaiah;Do Han Kim;Luis B. Agellon

  • Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells

    Ruth Halaban;Elaine Cheng;Yuhua Zhang;Gisela Moellmann

  • Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum.

    Pascal Gelebart;Michal Opas;Marek Michalak

  • Oligosaccharide binding characteristics of the molecular chaperones calnexin and calreticulin

    Aikaterini Vassilakos;Marek Michalak;Mark A. Lehrman;David B. Williams

  • Quality control in the endoplasmic reticulum

    Marek Michalak

Frequent Co-Authors

Michal Opas
Michal Opas University of Toronto
Paul Eggleton
Paul Eggleton University of Exeter
Larry Fliegel
Larry Fliegel University of Alberta
Lei Guo
Lei Guo National Center for Toxicological Research
Lukasz Kurgan
Lukasz Kurgan Virginia Commonwealth University
Gary D. Lopaschuk
Gary D. Lopaschuk University of Alberta
Karl-Heinz Krause
Karl-Heinz Krause University of Geneva
R. Chris Bleackley
R. Chris Bleackley University of Alberta
Marianne Sommarin
Marianne Sommarin Umeå University
Do Han Kim
Do Han Kim Gwangju Institute of Science and Technology

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